ID C7YZX4_NECH7 Unreviewed; 447 AA.
AC C7YZX4;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 06-MAR-2013, entry version 25.
DE RecName: Full=Mannose-6-phosphate isomerase;
DE EC=5.3.1.8;
GN ORFNames=NECHADRAFT_63158;
OS Nectria haematococca (strain 77-13-4 / ATCC MYA-4622 / FGSC 9596 /
OS MPVI) (Fusarium solani subsp. pisi).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
OC Sordariomycetes; Hypocreomycetidae; Hypocreales; Nectriaceae; Nectria;
OC Nectria haematococca complex.
OX NCBI_TaxID=660122;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI;
RX PubMed=19714214; DOI=10.1371/journal.pgen.1000618;
RA Coleman J.J., Rounsley S.D., Rodriguez-Carres M., Kuo A.,
RA Wasmann C.C., Grimwood J., Schmutz J., Taga M., White G.J., Zhou S.,
RA Schwartz D.C., Freitag M., Ma L.-J., Danchin E.G.J., Henrissat B.,
RA Coutinho P.M., Nelson D.R., Straney D., Napoli C.A., Barker B.M.,
RA Gribskov M., Rep M., Kroken S., Molnar I., Rensing C., Kennell J.C.,
RA Zamora J., Farman M.L., Selker E.U., Salamov A., Shapiro H.,
RA Pangilinan J., Lindquist E., Lamers C., Grigoriev I.V., Geiser D.M.,
RA Covert S.F., Temporini E., VanEtten H.D.;
RT "The genome of Nectria haematococca: contribution of supernumerary
RT chromosomes to gene expansion.";
RL PLoS Genet. 5:E1000618-E1000618(2009).
CC -!- CATALYTIC ACTIVITY: D-mannose 6-phosphate = D-fructose 6-
CC phosphate.
CC -!- COFACTOR: Binds 1 zinc ion per subunit (By similarity).
CC -!- PATHWAY: Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose
CC biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-
CC phosphate: step 1/2.
CC -!- SIMILARITY: Belongs to the mannose-6-phosphate isomerase type 1
CC family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; GG698904; EEU42688.1; -; Genomic_DNA.
DR RefSeq; XP_003048401.1; XM_003048355.1.
DR EnsemblFungi; NechaT63158; NechaP63158; NechaG63158.
DR GeneID; 9667478; -.
DR KEGG; nhe:NECHADRAFT_63158; -.
DR KO; K01809; -.
DR OrthoDB; EOG4TF3V5; -.
DR UniPathway; UPA00126; UER00423.
DR GO; GO:0004476; F:mannose-6-phosphate isomerase activity; IEA:EC.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0009298; P:GDP-mannose biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 2.60.120.10; -; 3.
DR InterPro; IPR001250; Man6P_Isoase-1.
DR InterPro; IPR016305; Mannose-6-P_Isomerase.
DR InterPro; IPR018050; Pmannose_isomerase-type1_CS.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR011051; RmlC_Cupin.
DR PANTHER; PTHR10309; PTHR10309; 1.
DR Pfam; PF01238; PMI_typeI; 1.
DR PIRSF; PIRSF001480; Mannose-6-phosphate_isomerase; 1.
DR PRINTS; PR00714; MAN6PISMRASE.
DR SUPFAM; SSF51182; RmlC_like_cupin; 1.
DR TIGRFAMs; TIGR00218; manA; 1.
DR PROSITE; PS00965; PMI_I_1; 1.
DR PROSITE; PS00966; PMI_I_2; 1.
PE 3: Inferred from homology;
KW Complete proteome; Isomerase; Reference proteome; Zinc.
SQ SEQUENCE 447 AA; 48408 MW; ADC7F906EEADFF70 CRC64;
MQVPLLRLQC GVNSYAWGKK GNESAAARFA AATPSDDLKI ESDTPYAELW MGTHPSNPSR
DVNTGRSLLE LVQDNKALLS STIISRYGEK LPFLFKVLSI NKALSIQAHP NKKLAEQLHA
RDPKNYPDDN HKPEMAIAIT PFEGLCGFRP LAEIAHFLES VPALRALVGD EAAAEFAKVA
KDEEEGVSED KKLLLKKVFG ALMNSPAEAI AEQTAKLVEQ ASSEGASFAA GGVAATSGEK
LSELVQRCHG EFGDDIGLFV LFFLNFVTLE PGEALFLVAD DIHAYISGDI MECMAASDNV
VRAGFTPKFK DVSTLVDMLT YNYAPIEEQK MSPTEYPYAT LNRSGYSSGS AVVLYDPPID
EFSVVRTLLR GDGAKATFEP LDGPSIVICT SGKGKISVGP TSAEIREGWV YFVGATAECV
LESEGGEDDE FTTYKAFCEI DDSKEKL
//
