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Database: UniProt/TrEMBL
Entry: C8VZ61_DESAS
LinkDB: C8VZ61_DESAS
Original site: C8VZ61_DESAS 
ID   C8VZ61_DESAS            Unreviewed;       364 AA.
AC   C8VZ61;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   16-APR-2014, entry version 34.
DE   RecName: Full=6-phosphofructokinase;
DE            Short=Phosphofructokinase;
DE            EC=2.7.1.11;
DE   AltName: Full=Phosphohexokinase;
GN   Name=pfkA; OrderedLocusNames=Dtox_2143;
OS   Desulfotomaculum acetoxidans (strain ATCC 49208 / DSM 771 / VKM
OS   B-1644).
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Peptococcaceae;
OC   Desulfotomaculum.
OX   NCBI_TaxID=485916;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49208 / DSM 771 / VKM B-1644;
RX   PubMed=21304664; DOI=10.4056/sigs.39508;
RA   Spring S., Lapidus A., Schroder M., Gleim D., Sims D., Meincke L.,
RA   Glavina Del Rio T., Tice H., Copeland A., Cheng J.F., Lucas S.,
RA   Chen F., Nolan M., Bruce D., Goodwin L., Pitluck S., Ivanova N.,
RA   Mavromatis K., Mikhailova N., Pati A., Chen A., Palaniappan K.,
RA   Land M., Hauser L., Chang Y.J., Jeffries C.D., Chain P., Saunders E.,
RA   Brettin T., Detter J.C., Goker M., Bristow J., Eisen J.A.,
RA   Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P., Han C.;
RT   "Complete genome sequence of Desulfotomaculum acetoxidans type strain
RT   (5575).";
RL   Stand. Genomic Sci. 1:242-253(2009).
CC   -!- CATALYTIC ACTIVITY: ATP + D-fructose 6-phosphate = ADP + D-
CC       fructose 1,6-bisphosphate.
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC       phosphate and glycerone phosphate from D-glucose: step 3/4.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the phosphofructokinase family.
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DR   EMBL; CP001720; ACV62971.1; -; Genomic_DNA.
DR   RefSeq; YP_003191594.1; NC_013216.1.
DR   ProteinModelPortal; C8VZ61; -.
DR   STRING; 485916.Dtox_2143; -.
DR   EnsemblBacteria; ACV62971; ACV62971; Dtox_2143.
DR   GeneID; 8429125; -.
DR   KEGG; dae:Dtox_2143; -.
DR   PATRIC; 21721157; VBIDesAce42372_2189.
DR   eggNOG; COG0205; -.
DR   HOGENOM; HOG000248869; -.
DR   KO; K00850; -.
DR   OMA; IPEIPYK; -.
DR   OrthoDB; EOG644ZRM; -.
DR   BioCyc; DACE485916:GHUF-2206-MONOMER; -.
DR   UniPathway; UPA00109; UER00182.
DR   GO; GO:0005945; C:6-phosphofructokinase complex; IEA:InterPro.
DR   GO; GO:0003872; F:6-phosphofructokinase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006002; P:fructose 6-phosphate metabolic process; IEA:InterPro.
DR   GO; GO:0006096; P:glycolysis; IEA:UniProtKB-HAMAP.
DR   HAMAP; MF_00339; Phosphofructokinase; 1.
DR   InterPro; IPR012003; ATP_PFK_prok.
DR   InterPro; IPR012829; PFK.
DR   InterPro; IPR022953; Phosphofructokinase.
DR   InterPro; IPR015912; Phosphofructokinase_CS.
DR   InterPro; IPR000023; Phosphofructokinase_dom.
DR   Pfam; PF00365; PFK; 1.
DR   PIRSF; PIRSF000532; ATP_PFK_prok; 1.
DR   PRINTS; PR00476; PHFRCTKINASE.
DR   SUPFAM; SSF53784; SSF53784; 1.
DR   TIGRFAMs; TIGR02483; PFK_mixed; 1.
DR   PROSITE; PS00433; PHOSPHOFRUCTOKINASE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; Glycolysis; Kinase;
KW   Magnesium; Metal-binding; Nucleotide-binding; Transferase.
FT   NP_BIND      26     30       ATP (By similarity).
FT   NP_BIND     170    174       ATP (By similarity).
FT   NP_BIND     187    203       ATP (By similarity).
FT   ACT_SITE    143    143       Proton acceptor (By similarity).
FT   METAL       201    201       Magnesium; via carbonyl oxygen (By
FT                                similarity).
FT   METAL       203    203       Magnesium (By similarity).
FT   BINDING     178    178       Substrate (By similarity).
FT   BINDING     282    282       Substrate (By similarity).
FT   BINDING     288    288       Substrate (By similarity).
FT   BINDING     291    291       Substrate (By similarity).
SQ   SEQUENCE   364 AA;  38669 MW;  989180F7B7E1399B CRC64;
     MLSGKIKKIG VLTGGGDCPG LNAVIRAIVK TAASYSISVV GILDGFGGLI HNQTWKLTEK
     DVMGILPRGG TILGTTNRDD PFNYPVIQDG KKVLADVSSQ VKNNLHQNEL DALIVIGGDG
     TLKIALGFHQ IGVPVIGVPK TIDNDLSATD QTFGFDTALT TATEAIDKLH TTAESHHRVM
     VLEVMGRYAG WIALQSGLAG GADVILLPEI PFQMSKVIGK IKERRDHGKK FSIIVVAEGA
     MPLGGHMVVQ KHIEDSPDPV RLGGIGNLVG VQVEEGTGME TRVTVLGHLQ RGGSPTAFDR
     ILATRYGNGA IHLLNSKKFG EMVCLRTPDI KSVPLSEAVG ELRQVSPEGQ MVKTAEQIGI
     CLGR
//
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