ID C8VZ61_DESAS Unreviewed; 364 AA.
AC C8VZ61;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 01-MAY-2013, entry version 29.
DE RecName: Full=6-phosphofructokinase;
DE Short=Phosphofructokinase;
DE EC=2.7.1.11;
DE AltName: Full=Phosphohexokinase;
GN Name=pfkA; OrderedLocusNames=Dtox_2143;
OS Desulfotomaculum acetoxidans (strain ATCC 49208 / DSM 771 / VKM
OS B-1644).
OC Bacteria; Firmicutes; Clostridia; Clostridiales; Peptococcaceae;
OC Desulfotomaculum.
OX NCBI_TaxID=485916;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49208 / DSM 771 / VKM B-1644;
RX PubMed=21304664; DOI=10.4056/sigs.39508;;
RA Spring S., Lapidus A., Schroder M., Gleim D., Sims D., Meincke L.,
RA Glavina Del Rio T., Tice H., Copeland A., Cheng J.F., Lucas S.,
RA Chen F., Nolan M., Bruce D., Goodwin L., Pitluck S., Ivanova N.,
RA Mavromatis K., Mikhailova N., Pati A., Chen A., Palaniappan K.,
RA Land M., Hauser L., Chang Y.J., Jeffries C.D., Chain P., Saunders E.,
RA Brettin T., Detter J.C., Goker M., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P., Han C.;
RT "Complete genome sequence of Desulfotomaculum acetoxidans type strain
RT (5575).";
RL Stand. Genomic Sci. 1:242-253(2009).
CC -!- CATALYTIC ACTIVITY: ATP + D-fructose 6-phosphate = ADP + D-
CC fructose 1,6-bisphosphate.
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC phosphate and glycerone phosphate from D-glucose: step 3/4.
CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC -!- SIMILARITY: Belongs to the phosphofructokinase family.
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DR EMBL; CP001720; ACV62971.1; -; Genomic_DNA.
DR RefSeq; YP_003191594.1; NC_013216.1.
DR ProteinModelPortal; C8VZ61; -.
DR STRING; 485916.Dtox_2143; -.
DR EnsemblBacteria; ACV62971; ACV62971; Dtox_2143.
DR GeneID; 8429125; -.
DR KEGG; dae:Dtox_2143; -.
DR PATRIC; 21721157; VBIDesAce42372_2189.
DR eggNOG; COG0205; -.
DR HOGENOM; HOG000248869; -.
DR KO; K00850; -.
DR OMA; TVPLERY; -.
DR BioCyc; DACE485916:GHUF-2206-MONOMER; -.
DR UniPathway; UPA00109; UER00182.
DR GO; GO:0005945; C:6-phosphofructokinase complex; IEA:InterPro.
DR GO; GO:0003872; F:6-phosphofructokinase activity; IEA:HAMAP.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006002; P:fructose 6-phosphate metabolic process; IEA:InterPro.
DR GO; GO:0006096; P:glycolysis; IEA:HAMAP.
DR HAMAP; MF_00339; Phosphofructokinase; 1; -.
DR InterPro; IPR012003; ATP_PFK_prok.
DR InterPro; IPR012829; PFK.
DR InterPro; IPR022953; Phosphofructokinase.
DR InterPro; IPR015912; Phosphofructokinase_CS.
DR InterPro; IPR000023; Phosphofructokinase_dom.
DR Pfam; PF00365; PFK; 1.
DR PIRSF; PIRSF000532; ATP_PFK_prok; 1.
DR PRINTS; PR00476; PHFRCTKINASE.
DR SUPFAM; SSF53784; Ppfruckinase; 1.
DR TIGRFAMs; TIGR02483; PFK_mixed; 1.
DR PROSITE; PS00433; PHOSPHOFRUCTOKINASE; 1.
PE 3: Inferred from homology;
KW ATP-binding; Complete proteome; Cytoplasm; Glycolysis; Kinase;
KW Magnesium; Metal-binding; Nucleotide-binding; Transferase.
FT NP_BIND 26 30 ATP (By similarity).
FT NP_BIND 170 174 ATP (By similarity).
FT NP_BIND 187 203 ATP (By similarity).
FT ACT_SITE 143 143 Proton acceptor (By similarity).
FT METAL 201 201 Magnesium; via carbonyl oxygen (By
FT similarity).
FT METAL 203 203 Magnesium (By similarity).
FT BINDING 178 178 Substrate (By similarity).
FT BINDING 282 282 Substrate (By similarity).
FT BINDING 288 288 Substrate (By similarity).
FT BINDING 291 291 Substrate (By similarity).
SQ SEQUENCE 364 AA; 38669 MW; 989180F7B7E1399B CRC64;
MLSGKIKKIG VLTGGGDCPG LNAVIRAIVK TAASYSISVV GILDGFGGLI HNQTWKLTEK
DVMGILPRGG TILGTTNRDD PFNYPVIQDG KKVLADVSSQ VKNNLHQNEL DALIVIGGDG
TLKIALGFHQ IGVPVIGVPK TIDNDLSATD QTFGFDTALT TATEAIDKLH TTAESHHRVM
VLEVMGRYAG WIALQSGLAG GADVILLPEI PFQMSKVIGK IKERRDHGKK FSIIVVAEGA
MPLGGHMVVQ KHIEDSPDPV RLGGIGNLVG VQVEEGTGME TRVTVLGHLQ RGGSPTAFDR
ILATRYGNGA IHLLNSKKFG EMVCLRTPDI KSVPLSEAVG ELRQVSPEGQ MVKTAEQIGI
CLGR
//
