ID D1BHD9_SANKS Unreviewed; 741 AA.
AC D1BHD9;
DT 19-JAN-2010, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN OrderedLocusNames=Sked_19340 {ECO:0000313|EMBL:ACZ21859.1};
OS Sanguibacter keddieii (strain ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Sanguibacteraceae;
OC Sanguibacter.
OX NCBI_TaxID=446469 {ECO:0000313|EMBL:ACZ21859.1, ECO:0000313|Proteomes:UP000000322};
RN [1] {ECO:0000313|EMBL:ACZ21859.1, ECO:0000313|Proteomes:UP000000322}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74
RC {ECO:0000313|Proteomes:UP000000322};
RX PubMed=21304646;
RA Ivanova N., Sikorski J., Sims D., Brettin T., Detter J.C., Han C.,
RA Lapidus A., Copeland A., Glavina Del Rio T., Nolan M., Chen F., Lucas S.,
RA Tice H., Cheng J.F., Bruce D., Goodwin L., Pitluck S., Pati A.,
RA Mavromatis K., Chen A., Palaniappan K., D'haeseleer P., Chain P.,
RA Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Goker M., Pukall R.,
RA Klenk H.P., Kyrpides N.C.;
RT "Complete genome sequence of Sanguibacter keddieii type strain (ST-74).";
RL Stand. Genomic Sci. 1:110-118(2009).
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DR EMBL; CP001819; ACZ21859.1; -; Genomic_DNA.
DR RefSeq; WP_012866928.1; NC_013521.1.
DR AlphaFoldDB; D1BHD9; -.
DR STRING; 446469.Sked_19340; -.
DR KEGG; ske:Sked_19340; -.
DR eggNOG; COG0365; Bacteria.
DR HOGENOM; CLU_000022_3_6_11; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000000322; Chromosome.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ACZ21859.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 58..123
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 130..518
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 579..667
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 706..741
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 722..741
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 741 AA; 80202 MW; 9427B0633315CC80 CRC64;
MTETIRTSPT PVASETAPGP LQPGGSSSIS VVQTEDRTYP APQAFAEKAN VDRAEHDRLL
AEGEQDPVGF WERAAGRLRW DTPWHTAHTW SPAVPVEGGE EGELTVPEAR WFLGGRLNVA
VNCVDRHVDE GRGDKVAIYA EGERGDRRAI TYAELQDEVS RAANALTALG VGEGDRVIVY
LPVIAETIVV TLAIARIGAI HSLVFGGFSA EAVRFRVEDT GAKLLVTSDG QFRRGAAVEV
KSAADAAVAG LDHVEHVLVV RRTGQDVAWT PGRDVWWHDV VDTASPVHEA RSFDSETPLF
IIYTSGTTGK PKGLLHTSGG YLTQASWTHW AHFDAKPDDV HWCTADLAWV TAHTYEIYGP
LANGLTQVIY EGTPDTPSRT RHLEIIERYG VTTYYTAPTL IRTLMTWFPD GLPPEHDLSS
VRLLGTVGEA INPEAWVWFR EQLGAGTAPV VDTWWQSETG ATMIAPLPGS STLKPGSATR
PSPGLSVKVV DEAGAEVPYG SGGRLVVDRP WPGMARTIWR DPQRYLDAYW RTYAGAGADG
QGYFLAGDGA SYDADGDIWL LGRLDDVINV SGHRLSTIEI ESALVAHPGV GEAGVAGVDD
PVTGQAITAF VIPSRAPAAL DDTAAWRAAS AAVQDELRAH VATAIGPVAK PRRVVLVPDL
PKTRSGKIMR RLLAQVHDRT TLGDVTSLQN AHVLDQIHHL LHGEENVPVP QPDLAQQTEP
AQQEQHDEHD TQHHATKELS R
//
