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Database: UniProt/TrEMBL
Entry: D2H842_AILME
LinkDB: D2H842_AILME
Original site: D2H842_AILME 
ID   D2H842_AILME            Unreviewed;       379 AA.
AC   D2H842;
DT   09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT   09-FEB-2010, sequence version 1.
DT   30-AUG-2017, entry version 44.
DE   SubName: Full=Neuraminidase 2 {ECO:0000313|Ensembl:ENSAMEP00000017315};
DE   Flags: Fragment;
GN   Name=NEU2 {ECO:0000313|Ensembl:ENSAMEP00000017315};
GN   ORFNames=PANDA_006378 {ECO:0000313|EMBL:EFB20651.1};
OS   Ailuropoda melanoleuca (Giant panda).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae;
OC   Ailuropoda.
OX   NCBI_TaxID=9646;
RN   [1] {ECO:0000313|EMBL:EFB20651.1, ECO:0000313|Ensembl:ENSAMEP00000017315}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=20010809; DOI=10.1038/nature08696;
RA   Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q.,
RA   Li B., Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H.,
RA   Jian M., Li J., Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z.,
RA   Ryder O.A., Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X.,
RA   Guo X., Wang B., Hou R., Shen F., Mu B., Ni P., Lin R., Qian W.,
RA   Wang G., Yu C., Nie W., Wang J., Wu Z., Liang H., Min J., Wu Q.,
RA   Cheng S., Ruan J., Wang M., Shi Z., Wen M., Liu B., Ren X., Zheng H.,
RA   Dong D., Cook K., Shan G., Zhang H., Kosiol C., Xie X., Lu Z.,
RA   Zheng H., Li Y., Steiner C.C., Lam T.T., Lin S., Zhang Q., Li G.,
RA   Tian J., Gong T., Liu H., Zhang D., Fang L., Ye C., Zhang J., Hu W.,
RA   Xu A., Ren Y., Zhang G., Bruford M.W., Li Q., Ma L., Guo Y., An N.,
RA   Hu Y., Zheng Y., Shi Y., Li Z., Liu Q., Chen Y., Zhao J., Qu N.,
RA   Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X., Vinar T., Wang Y.,
RA   Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y., Wang X.,
RA   Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA   Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H.,
RA   Wang J., Wang J.;
RT   "The sequence and de novo assembly of the giant panda genome.";
RL   Nature 463:311-317(2010).
RN   [2] {ECO:0000313|Ensembl:ENSAMEP00000017315}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
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DR   EMBL; ACTA01192607; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; GL192569; EFB20651.1; -; Genomic_DNA.
DR   RefSeq; XP_002918012.1; XM_002917966.2.
DR   STRING; 9646.ENSAMEP00000017315; -.
DR   Ensembl; ENSAMET00000018025; ENSAMEP00000017315; ENSAMEG00000016400.
DR   GeneID; 100464404; -.
DR   KEGG; aml:100464404; -.
DR   CTD; 4759; -.
DR   eggNOG; ENOG410IFVF; Eukaryota.
DR   eggNOG; ENOG410Y74Z; LUCA.
DR   GeneTree; ENSGT00390000011171; -.
DR   HOGENOM; HOG000233778; -.
DR   KO; K12357; -.
DR   OMA; QDTLECQ; -.
DR   OrthoDB; EOG091G08BI; -.
DR   TreeFam; TF331063; -.
DR   Proteomes; UP000008912; Unassembled WGS sequence.
DR   GO; GO:1902494; C:catalytic complex; IEA:Ensembl.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0052794; F:exo-alpha-(2->3)-sialidase activity; IEA:Ensembl.
DR   GO; GO:0051692; P:cellular oligosaccharide catabolic process; IEA:Ensembl.
DR   GO; GO:0006689; P:ganglioside catabolic process; IEA:Ensembl.
DR   InterPro; IPR026945; Sialidase-2.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR011040; Sialidases.
DR   PANTHER; PTHR10628; PTHR10628; 1.
DR   PANTHER; PTHR10628:SF27; PTHR10628:SF27; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; SSF50939; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008912};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008912}.
FT   DOMAIN       33    340       Sialidases. {ECO:0000259|Pfam:PF13088}.
FT   NON_TER     379    379       {ECO:0000313|EMBL:EFB20651.1}.
SQ   SEQUENCE   379 AA;  42134 MW;  88AC8D26ADB7898C CRC64;
     MASCPVLQKE RVFQSGDHAY RIPALLYLPQ QKTLLAFAEK RMSKKDEHAE LIVLRRGSYD
     ASTHHVQWHA QEVVAQAQLE GHRSMNPSPL YDEKTGTLFL FFIAIPGQVS EHHQIHTRVN
     VTRLCQVTST NHGRSWSPAR DLTGPAIGAA HKEWATFAVG PGHCLQLHNK TQSLVVPAYA
     YRNLHSIQGP SPFAFCFVSH DHGHTWKRGN FVAQDTLECQ VAEVGGARQR VVYLNARSPL
     RARVQAESTN EGLDFQEAQT VKKLVEPPHG CHGSVISFPN PREGSGASDK WLLYTHPTDP
     QQRADLGVYL NKRLPGPEAW SEPALLATGS CAYSDLQSMG VGPDGSPQFG CLYESDNYEE
     VVFLMFTLKQ AFPAEFLSQ
//
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