ID   D3EKK7_GEOS4            Unreviewed;       252 AA.
AC   D3EKK7;
DT   23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   23-MAR-2010, sequence version 1.
DT   01-MAY-2013, entry version 19.
DE   RecName: Full=Ribonuclease PH;
DE            Short=RNase PH;
DE            EC=2.7.7.56;
DE   AltName: Full=tRNA nucleotidyltransferase;
GN   Name=rph; OrderedLocusNames=GYMC10_1492;
OS   Geobacillus sp. (strain Y412MC10).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Paenibacillaceae;
OC   Paenibacillus.
OX   NCBI_TaxID=481743;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Y412MC10;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Ovchinnikova G., Brumm P., Mead D.;
RT   "Complete sequence of Geobacillus sp. Y412MC10.";
RL   Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Phosphorolytic exoribonuclease that removes nucleotide
CC       residues following the -CCA terminus of tRNA and adds nucleotides
CC       to the ends of RNA molecules by using nucleoside diphosphates as
CC       substrates (By similarity).
CC   -!- CATALYTIC ACTIVITY: tRNA(n+1) + phosphate = tRNA(n) + a nucleoside
CC       diphosphate.
CC   -!- SIMILARITY: Belongs to the RNase PH family.
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DR   EMBL; CP001793; ACX63777.1; -; Genomic_DNA.
DR   RefSeq; YP_003241584.1; NC_013406.1.
DR   EnsemblBacteria; ACX63777; ACX63777; GYMC10_1492.
DR   GeneID; 8515655; -.
DR   KEGG; gym:GYMC10_1492; -.
DR   PATRIC; 32151537; VBIGeoSp56627_1500.
DR   HOGENOM; HOG000229516; -.
DR   KO; K00989; -.
DR   OMA; MLPRATG; -.
DR   BioCyc; PSP481743:GH8K-1518-MONOMER; -.
DR   GO; GO:0000049; F:tRNA binding; IEA:HAMAP.
DR   GO; GO:0009022; F:tRNA nucleotidyltransferase activity; IEA:HAMAP.
DR   GO; GO:0004549; F:tRNA-specific ribonuclease activity; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; IEA:HAMAP.
DR   HAMAP; MF_00564; RNase_PH; 1; -.
DR   InterPro; IPR001247; ExoRNase_PH_dom1.
DR   InterPro; IPR015847; ExoRNase_PH_dom2.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   InterPro; IPR002381; RNase_PH_bac-type.
DR   InterPro; IPR018336; RNase_PH_CS.
DR   Pfam; PF01138; RNase_PH; 1.
DR   Pfam; PF03725; RNase_PH_C; 1.
DR   SUPFAM; SSF55666; 3_ExoRNase; 1.
DR   SUPFAM; SSF54211; Ribosomal_S5_D2-typ_fold; 1.
DR   TIGRFAMs; TIGR01966; RNasePH; 1.
DR   PROSITE; PS01277; RIBONUCLEASE_PH; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Nucleotidyltransferase; Transferase;
KW   tRNA processing.
SQ   SEQUENCE   252 AA;  27289 MW;  275D8585BAD00421 CRC64;
     MRSNGRKSDE LRPMNLSTHV NKYAEGSVYI EMGDTKVLIT ATVDEKVPPF LKGQGKGWVT
     AEYSMLPRAT QSRNQREANR GKLSGRTMEI QRLIGRALRS VVNLHALGER TITLDCDVIQ
     ADGGTRTTSI TGAFVALAIA VNKIAEQHKL AVFPITDYLA SISVGIAGGQ ALLDLNYEED
     SKAKVDMNLV MTGSGKFVEV QGTGEESPFS REELDQILEL GEQGIRELIE RQQEALGPIA
     AKIGSVNAST GV
//