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Database: UniProt/TrEMBL
Entry: D3NXD0_AZOS1
LinkDB: D3NXD0_AZOS1
Original site: D3NXD0_AZOS1 
ID   D3NXD0_AZOS1            Unreviewed;       533 AA.
AC   D3NXD0;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   26-NOV-2014, entry version 30.
DE   SubName: Full=2-isopropylmalate synthase {ECO:0000313|EMBL:BAI73059.1};
DE            EC=2.3.3.13 {ECO:0000313|EMBL:BAI73059.1};
GN   Name=leuA {ECO:0000313|EMBL:BAI73059.1};
GN   OrderedLocusNames=AZL_024210 {ECO:0000313|EMBL:BAI73059.1};
OS   Azospirillum sp. (strain B510).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Rhodospirillaceae; Azospirillum.
OX   NCBI_TaxID=137722 {ECO:0000313|EMBL:BAI73059.1, ECO:0000313|Proteomes:UP000002040};
RN   [1] {ECO:0000313|EMBL:BAI73059.1, ECO:0000313|Proteomes:UP000002040}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B510 {ECO:0000313|EMBL:BAI73059.1,
RC   ECO:0000313|Proteomes:UP000002040};
RX   PubMed=20047946; DOI=10.1093/dnares/dsp026;
RA   Kaneko T., Minamisawa K., Isawa T., Nakatsukasa H., Mitsui H.,
RA   Kawaharada Y., Nakamura Y., Watanabe A., Kawashima K., Ono A.,
RA   Shimizu Y., Takahashi C., Minami C., Fujishiro T., Kohara M.,
RA   Katoh M., Nakazaki N., Nakayama S., Yamada M., Tabata S., Sato S.;
RT   "Complete genomic structure of the cultivated rice endophyte
RT   Azospirillum sp. B510.";
RL   DNA Res. 17:37-50(2010).
CC   -!- SIMILARITY: Belongs to the alpha-IPM synthase/homocitrate synthase
CC       family. {ECO:0000256|RuleBase:RU003523}.
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DR   EMBL; AP010946; BAI73059.1; -; Genomic_DNA.
DR   RefSeq; YP_003449603.1; NC_013854.1.
DR   ProteinModelPortal; D3NXD0; -.
DR   EnsemblBacteria; BAI73059; BAI73059; AZL_024210.
DR   GeneID; 8790887; -.
DR   KEGG; azl:AZL_024210; -.
DR   PATRIC; 31934037; VBIAzoSp82869_2636.
DR   HOGENOM; HOG000046860; -.
DR   KO; K01649; -.
DR   BioCyc; ASP137722:GBYD-2463-MONOMER; -.
DR   GO; GO:0003852; F:2-isopropylmalate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009098; P:leucine biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013709; 2-isopropylmalate_synth_dimer.
DR   InterPro; IPR002034; AIPM/Hcit_synth_CS.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR005675; LeuA-rel.
DR   InterPro; IPR000891; PYR_CT.
DR   PANTHER; PTHR10277:SF5; PTHR10277:SF5; 1.
DR   Pfam; PF00682; HMGL-like; 1.
DR   Pfam; PF08502; LeuA_dimer; 1.
DR   SMART; SM00917; LeuA_dimer; 1.
DR   SUPFAM; SSF110921; SSF110921; 1.
DR   TIGRFAMs; TIGR00977; LeuA_rel; 1.
DR   PROSITE; PS00815; AIPM_HOMOCIT_SYNTH_1; 1.
DR   PROSITE; PS50991; PYR_CT; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000313|EMBL:BAI73059.1};
KW   Amino-acid biosynthesis {ECO:0000256|SAAS:SAAS00161119};
KW   Branched-chain amino acid biosynthesis
KW   {ECO:0000256|SAAS:SAAS00161122};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002040};
KW   Transferase {ECO:0000256|RuleBase:RU003523,
KW   ECO:0000256|SAAS:SAAS00108429}.
SQ   SEQUENCE   533 AA;  58237 MW;  C041E53542E1DC92 CRC64;
     MTGERIYLYD TTLRDGAQTQ DVDFSVADKI AIARDLDRLG IDYIEGGWPG ANPTDDRFFA
     EAPELSRAIF TAFGMTRRPG RSAANDPQLT ALAQSRAKAV CMVGKSWDFH VDVALNIPRA
     ENLDLIRDSI AALRAAKGEA LFDAEHFFDG YKRNPAYAVS CIKAAQDAGA RWIVLCDTNG
     GTLPHEIDAI VREVVETHGI PGDQLGIHCH NDTENAVANS LAAVRAGARM VQGTINGLGE
     RCGNANLVSL IPTLMLKMGY ETGIRREDLP LLTQLSRAFD DRLNRAPNRH APYVGASAFA
     HKGGLHVSAV EKDPSSYEHV APDAIGNRRQ IVMSDQAGRS NLIARLRDIG MAVDAKDERL
     TGLLDLVKRR DSDGYAYDTA EASFELLVRR ELGEVPRFFE LLRFHVTDER RYNAVGEMVV
     ESEAVVRVRI GDELRMEVAD GNGPVHALDV AMRKALEPAY PALAKVSLSD YRVRILAAKD
     GTGAMPRVLI RSARTDGTEW STLGVSTNII EASMEALVDS YTYALMKGDA TPV
//
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