ID D3S6J6_METSF Unreviewed; 427 AA.
AC D3S6J6;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 01-MAY-2013, entry version 23.
DE RecName: Full=Probable 3-phosphoshikimate 1-carboxyvinyltransferase;
DE EC=2.5.1.19;
DE AltName: Full=5-enolpyruvylshikimate-3-phosphate synthase;
GN Name=aroA; OrderedLocusNames=MFS40622_1790;
OS Methanocaldococcus sp. (strain FS406-22).
OC Archaea; Euryarchaeota; Methanococci; Methanococcales;
OC Methanocaldococcaceae; Methanocaldococcus.
OX NCBI_TaxID=644281;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FS406-22;
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Teshima H., Detter J.C., Han C., Tapia R., Larimer F.,
RA Land M., Hauser L., Kyrpides N., Mikhailova N., Sieprawska-Lupa M.,
RA Leigh J., Whitman W.B., Woyke T.;
RT "Complete sequence of chromosome of Methanocaldococcus sp. FS406-22.";
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY: Phosphoenolpyruvate + 3-phosphoshikimate =
CC phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate.
CC -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC biosynthesis; chorismate from D-erythrose 4-phosphate and
CC phosphoenolpyruvate: step 6/7.
CC -!- SUBUNIT: Monomer (By similarity).
CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC -!- SIMILARITY: Belongs to the EPSP synthase family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; CP001901; ADC70460.1; -; Genomic_DNA.
DR RefSeq; YP_003459196.1; NC_013887.1.
DR ProteinModelPortal; D3S6J6; -.
DR EnsemblBacteria; ADC70460; ADC70460; MFS40622_1790.
DR GeneID; 8805665; -.
DR KEGG; mfs:MFS40622_1790; -.
DR HOGENOM; HOG000247372; -.
DR KO; K00800; -.
DR OMA; SNAGPFL; -.
DR BioCyc; MSP644281:GI4H-1845-MONOMER; -.
DR UniPathway; UPA00053; UER00089.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003866; F:3-phosphoshikimate 1-carboxyvinyltransferase activity; IEA:HAMAP.
DR GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:HAMAP.
DR GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.65.10.10; -; 2.
DR HAMAP; MF_00210; EPSP_synth; 1; -.
DR InterPro; IPR001986; Enolpyruvate_Tfrase_dom.
DR InterPro; IPR006264; EPSP_synthase.
DR InterPro; IPR023193; EPSP_synthase_CS.
DR InterPro; IPR013792; RNA3'P_cycl/enolpyr_Trfase_a/b.
DR Pfam; PF00275; EPSP_synthase; 1.
DR PIRSF; PIRSF000505; EPSPS; 1.
DR SUPFAM; SSF55205; RNA3'_cycl/enolpyr_transf_A/B; 1.
DR TIGRFAMs; TIGR01356; aroA; 1.
DR PROSITE; PS00104; EPSP_SYNTHASE_1; 1.
DR PROSITE; PS00885; EPSP_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis; Aromatic amino acid biosynthesis;
KW Complete proteome; Cytoplasm; Transferase.
SQ SEQUENCE 427 AA; 46557 MW; 2B1B2B90C3A88AF6 CRC64;
MLIVKKTDRL EGIVKAPPSK SYTHRAVIGA SLAEGISRII NPLWGADCLS SVHGCKMLGA
DITLDKEKDE WVVKGGELKT PDNIIDIGNS GTTLRILTSI ASQIPKGYAI LTGDESIRKR
PMQPLLDALK QLNIEAFSSK LDGTAPIIVK SGKIDGNVVK IRGDISSQFI TSLMMLLPFN
KEDTEIILTS PLKSKPYIDI TLDILNNFGI KIDKTDNGFL VYGNQKYKPI DYIVEGDYSS
ASYLIAAGVL INSNITIENL FANSKQGDKA IINIVKEMGA DVKVKKDRVI IEGEYSLEGI
DVDVKDIPDL VPTIAVLGCF AEGKTEIYNG EHVRLKECDR LRACAVELKK MGADIEEKPD
GLIIRGVKKL KGAKLNTYHD HRLVMAFTIA GLKAEGETII EGEEAVKISF PNFVDVMKSL
GANIVVG
//
