ID D3T3T6_THEIA Unreviewed; 574 AA.
AC D3T3T6;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Alpha amylase catalytic region {ECO:0000313|EMBL:ADD02888.1};
GN OrderedLocusNames=Thit_1637 {ECO:0000313|EMBL:ADD02888.1};
OS Thermoanaerobacter italicus (strain DSM 9252 / Ab9).
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Thermoanaerobacter.
OX NCBI_TaxID=580331 {ECO:0000313|EMBL:ADD02888.1, ECO:0000313|Proteomes:UP000001552};
RN [1] {ECO:0000313|EMBL:ADD02888.1, ECO:0000313|Proteomes:UP000001552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 9252 / JCM 16815 / Ab9 {ECO:0000313|Proteomes:UP000001552};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Mikhailova N., Hemme C.L., Woyke T.;
RT "Complete sequence of Thermoanaerobacter italicus Ab9.";
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 13 family.
CC {ECO:0000256|ARBA:ARBA00008061}.
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DR EMBL; CP001936; ADD02888.1; -; Genomic_DNA.
DR RefSeq; WP_012995615.1; NC_013921.1.
DR AlphaFoldDB; D3T3T6; -.
DR CAZy; CBM34; Carbohydrate-Binding Module Family 34.
DR CAZy; GH13; Glycoside Hydrolase Family 13.
DR KEGG; tit:Thit_1637; -.
DR eggNOG; COG0366; Bacteria.
DR HOGENOM; CLU_006462_6_2_9; -.
DR OrthoDB; 9805159at2; -.
DR Proteomes; UP000001552; Chromosome.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd11338; AmyAc_CMD; 1.
DR CDD; cd02857; E_set_CDase_PDE_N; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR InterPro; IPR004185; Glyco_hydro_13_lg-like_dom.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR045857; O16G_dom_2.
DR PANTHER; PTHR10357; ALPHA-AMYLASE FAMILY MEMBER; 1.
DR PANTHER; PTHR10357:SF234; INTRACELLULAR MALTOGENIC AMYLASE; 1.
DR Pfam; PF00128; Alpha-amylase; 1.
DR Pfam; PF02903; Alpha-amylase_N; 1.
DR SMART; SM00642; Aamy; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE 3: Inferred from homology;
FT DOMAIN 136..494
FT /note="Glycosyl hydrolase family 13 catalytic"
FT /evidence="ECO:0000259|SMART:SM00642"
SQ SEQUENCE 574 AA; 67858 MW; 915CF4028F9C7CB0 CRC64;
MIKEAIFHKS DVPYAYPVNE NQLKIVLRTA VFDVDRVYVL YKDRYDWMGK FKIKPMVLIH
TNELFDYFET TLDLNKKFVY FFYLVSEGGE KLYYTEAGFY KKRPEDGFWG FFHYPYIGEK
DVFFAPNWTS DCIVYQIFPE RFNNGDKSND PENVKPWGQK PTADSFFGGD LQGIIDKINY
LKDLGINAIY LTPIFLSPST HKYDTTDYYT IDPRFGDTQK ARELVQKCHD NGIKVIFDAV
FNHCGYDFFA FQDVIKNGEK SKYWDWFNIY EWPIKTHPKP SYEAFADTVW RMPKLMTKNP
EVQKYLLEVA EYWIKEVDID GWRLDVANEI DHHFWKKFRE VVKTAKPEAI IVGEVWHDAS
PWLRGDEFDS VMNYPFRNAV VDFFAKRKIS ASRFNTLITE QLMRHMESVN RVMFNLIGSH
DTERFLTLAN GMVTRMKLAL VFQFTFVGIP YIYYGDEVGM VGGNDPDCRR CMIWEEEKQN
RSIFDFYKKL ISIRKESEEL KYGNFCTLYA IGMVFAFKRE YKGKSIIVVL NNSSKQEVIF
LNEVEGKEDI LKMKELRRSG NLLYLQPNSA YILK
//
