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Database: UniProt/TrEMBL
Entry: D4B2Y3_ARTBC
LinkDB: D4B2Y3_ARTBC
Original site: D4B2Y3_ARTBC 
ID   D4B2Y3_ARTBC            Unreviewed;       474 AA.
AC   D4B2Y3;
DT   18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT   18-MAY-2010, sequence version 1.
DT   07-JUN-2017, entry version 42.
DE   SubName: Full=Histone-lysine N-methyltransferase Clr4 {ECO:0000313|EMBL:EFE30279.1};
GN   ORFNames=ARB_02816 {ECO:0000313|EMBL:EFE30279.1};
OS   Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371)
OS   (Trichophyton mentagrophytes).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX   NCBI_TaxID=663331 {ECO:0000313|EMBL:EFE30279.1, ECO:0000313|Proteomes:UP000008866};
RN   [1] {ECO:0000313|Proteomes:UP000008866}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4681 / CBS 112371 {ECO:0000313|Proteomes:UP000008866};
RX   PubMed=21247460; DOI=10.1186/gb-2011-12-1-r7;
RA   Burmester A., Shelest E., Gloeckner G., Heddergott C., Schindler S.,
RA   Staib P., Heidel A., Felder M., Petzold A., Szafranski K.,
RA   Feuermann M., Pedruzzi I., Priebe S., Groth M., Winkler R., Li W.,
RA   Kniemeyer O., Schroeckh V., Hertweck C., Hube B., White T.C.,
RA   Platzer M., Guthke R., Heitman J., Woestemeyer J., Zipfel P.F.,
RA   Monod M., Brakhage A.A.;
RT   "Comparative and functional genomics provide insights into the
RT   pathogenicity of dermatophytic fungi.";
RL   Genome Biol. 12:R7.1-R7.16(2011).
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + L-lysine-[histone] =
CC       S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
CC       {ECO:0000256|SAAS:SAAS00591578}.
CC   -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|SAAS:SAAS00563877}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|SAAS:SAAS00574581}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EFE30279.1}.
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DR   EMBL; ABSU01000031; EFE30279.1; -; Genomic_DNA.
DR   RefSeq; XP_003010919.1; XM_003010873.1.
DR   STRING; 663331.XP_003010919.1; -.
DR   EnsemblFungi; EFE30279; EFE30279; ARB_02816.
DR   GeneID; 9525035; -.
DR   KEGG; abe:ARB_02816; -.
DR   eggNOG; KOG1082; Eukaryota.
DR   eggNOG; COG2940; LUCA.
DR   KO; K11419; -.
DR   OrthoDB; EOG092C2EWO; -.
DR   Proteomes; UP000008866; Unassembled WGS sequence.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   InterPro; IPR003616; Post-SET_dom.
DR   InterPro; IPR007728; Pre-SET_dom.
DR   InterPro; IPR001214; SET_dom.
DR   Pfam; PF05033; Pre-SET; 1.
DR   Pfam; PF00856; SET; 1.
DR   SMART; SM00468; PreSET; 1.
DR   SMART; SM00317; SET; 1.
DR   PROSITE; PS50868; POST_SET; 1.
DR   PROSITE; PS50280; SET; 1.
PE   4: Predicted;
KW   Chromosome {ECO:0000256|SAAS:SAAS00508265};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008866};
KW   Methyltransferase {ECO:0000256|SAAS:SAAS00590675,
KW   ECO:0000313|EMBL:EFE30279.1};
KW   Nucleus {ECO:0000256|SAAS:SAAS00574642};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008866};
KW   S-adenosyl-L-methionine {ECO:0000256|SAAS:SAAS00591079};
KW   Transferase {ECO:0000256|SAAS:SAAS00591533,
KW   ECO:0000313|EMBL:EFE30279.1}.
FT   DOMAIN      290    420       SET. {ECO:0000259|PROSITE:PS50280}.
FT   DOMAIN      431    447       Post-SET. {ECO:0000259|PROSITE:PS50868}.
SQ   SEQUENCE   474 AA;  53588 MW;  ED1F1608F24E4C62 CRC64;
     MVTVLDSDSD EETFIQPEVI SSRLLKAFIS PEDDRQRQSP SKPPSKPRRA VVDKGSTSSS
     SRPQSKASNV SVVIPVPPRR PSPSPVTTSR KRSLSSDGDI NKALSRKLTA TKIPDHHGLS
     DFYAVESGEV KRPYLKLKTF DPKKTEIPRS SKRYIPPKRR SDKESACSRL EELYNKKLQR
     IKGPPIRFKA GKIAKEIDFN FDFIDSYKIH SGVNQIDPEF LWGCDCTKCD AECDCLSKDL
     VHYEKGRRVR AVLKSEILNK RTALIRECSS RCKCSGVNCW NHVVFRGRQV ELEVFQTKNR
     GFGVRSPHSI ERGQFIDTYV GEVIEPSTSD AREEAIDVEK YSSYLFSLDY FPGEEYEKEK
     DIYVVDGRKF GSITRFMNHS CNPNCKMFPA TQTDDHGVYQ LAFFAVRDIP AGTELTFDYH
     PGWEGGDVDP DATKCLCGEK NCRGQLWPAK RKTTRPGEDS SSSGESSEES EDDE
//
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