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Database: UniProt/TrEMBL
Entry: D4D4A1_TRIVH
LinkDB: D4D4A1_TRIVH
Original site: D4D4A1_TRIVH 
ID   D4D4A1_TRIVH            Unreviewed;       482 AA.
AC   D4D4A1;
DT   18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT   18-MAY-2010, sequence version 1.
DT   07-JUN-2017, entry version 39.
DE   SubName: Full=Histone-lysine N-methyltransferase Clr4 {ECO:0000313|EMBL:EFE43356.1};
GN   ORFNames=TRV_01916 {ECO:0000313|EMBL:EFE43356.1};
OS   Trichophyton verrucosum (strain HKI 0517).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX   NCBI_TaxID=663202 {ECO:0000313|EMBL:EFE43356.1, ECO:0000313|Proteomes:UP000008383};
RN   [1] {ECO:0000313|Proteomes:UP000008383}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HKI 0517 {ECO:0000313|Proteomes:UP000008383};
RX   PubMed=21247460; DOI=10.1186/gb-2011-12-1-r7;
RA   Burmester A., Shelest E., Gloeckner G., Heddergott C., Schindler S.,
RA   Staib P., Heidel A., Felder M., Petzold A., Szafranski K.,
RA   Feuermann M., Pedruzzi I., Priebe S., Groth M., Winkler R., Li W.,
RA   Kniemeyer O., Schroeckh V., Hertweck C., Hube B., White T.C.,
RA   Platzer M., Guthke R., Heitman J., Woestemeyer J., Zipfel P.F.,
RA   Monod M., Brakhage A.A.;
RT   "Comparative and functional genomics provide insights into the
RT   pathogenicity of dermatophytic fungi.";
RL   Genome Biol. 12:R7.1-R7.16(2011).
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + L-lysine-[histone] =
CC       S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
CC       {ECO:0000256|SAAS:SAAS00591578}.
CC   -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|SAAS:SAAS00563877}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|SAAS:SAAS00574581}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EFE43356.1}.
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DR   EMBL; ACYE01000100; EFE43356.1; -; Genomic_DNA.
DR   RefSeq; XP_003023974.1; XM_003023928.1.
DR   STRING; 663202.XP_003023974.1; -.
DR   EnsemblFungi; EFE43356; EFE43356; TRV_01916.
DR   GeneID; 9582667; -.
DR   KEGG; tve:TRV_01916; -.
DR   eggNOG; KOG1082; Eukaryota.
DR   eggNOG; COG2940; LUCA.
DR   KO; K11419; -.
DR   OrthoDB; EOG092C2EWO; -.
DR   Proteomes; UP000008383; Unassembled WGS sequence.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   InterPro; IPR003616; Post-SET_dom.
DR   InterPro; IPR007728; Pre-SET_dom.
DR   InterPro; IPR001214; SET_dom.
DR   Pfam; PF05033; Pre-SET; 1.
DR   Pfam; PF00856; SET; 1.
DR   SMART; SM00468; PreSET; 1.
DR   SMART; SM00317; SET; 1.
DR   PROSITE; PS50868; POST_SET; 1.
DR   PROSITE; PS50280; SET; 1.
PE   4: Predicted;
KW   Chromosome {ECO:0000256|SAAS:SAAS00508265};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008383};
KW   Methyltransferase {ECO:0000256|SAAS:SAAS00590675,
KW   ECO:0000313|EMBL:EFE43356.1};
KW   Nucleus {ECO:0000256|SAAS:SAAS00574642};
KW   S-adenosyl-L-methionine {ECO:0000256|SAAS:SAAS00591079};
KW   Transferase {ECO:0000256|SAAS:SAAS00591533,
KW   ECO:0000313|EMBL:EFE43356.1}.
FT   DOMAIN      299    429       SET. {ECO:0000259|PROSITE:PS50280}.
FT   DOMAIN      440    456       Post-SET. {ECO:0000259|PROSITE:PS50868}.
SQ   SEQUENCE   482 AA;  54540 MW;  318937D095E2235D CRC64;
     MPTQIPGQAV TRQLDTVIYS EHFWQPEVIS SRLLKAFISP EDDRQRQLPS KPPSKPGRAV
     VDKGSTSSSS RPQSKASNVS VVIPVPPRRP SPSPVTTSRK RSLSSDGDIN KALSRKLTAT
     KIPDHHGLSD FYAVGNEEVK RPYLKLKTFD PKKTEIPRSS KRYIPPKRRS DKESACSRLE
     ELYNKKLQRI KGPPVRFKAG KIAKEIDFNF DFIDSYKIHS GVNQIDPEFL WGCDCTKCDA
     ECDCLSKDLI HYEKGQRVRA VLKSEILNKR TALIRECSSR CKCSGVNCWN HVVFRGRQVE
     LEVFQTKNRG FGVRSPHSIE RGQFIDTYVG EVIEPSTSDA REEAIDVEKY SSYLFSLDYF
     PAEEYEKEKD IYVVDGRKFG SITRFINHSC NPNCKMFPAT QTDDHGVYQL AFFAVRDIPA
     GTELTFDYHP GWEGGDVDPD ATKCLCGEKN CRGQLWPAKR KTTRPGEDSS SGESSEESED
     DE
//
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