GenomeNet

Database: UniProt/TrEMBL
Entry: D4D7T9_TRIVH
LinkDB: D4D7T9_TRIVH
Original site: D4D7T9_TRIVH 
ID   D4D7T9_TRIVH            Unreviewed;      1012 AA.
AC   D4D7T9;
DT   18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT   18-MAY-2010, sequence version 1.
DT   25-OCT-2017, entry version 39.
DE   RecName: Full=DNA ligase {ECO:0000256|RuleBase:RU000617};
DE            EC=6.5.1.1 {ECO:0000256|RuleBase:RU000617};
GN   ORFNames=TRV_03173 {ECO:0000313|EMBL:EFE42094.1};
OS   Trichophyton verrucosum (strain HKI 0517).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX   NCBI_TaxID=663202 {ECO:0000313|EMBL:EFE42094.1, ECO:0000313|Proteomes:UP000008383};
RN   [1] {ECO:0000313|Proteomes:UP000008383}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HKI 0517 {ECO:0000313|Proteomes:UP000008383};
RX   PubMed=21247460; DOI=10.1186/gb-2011-12-1-r7;
RA   Burmester A., Shelest E., Gloeckner G., Heddergott C., Schindler S.,
RA   Staib P., Heidel A., Felder M., Petzold A., Szafranski K.,
RA   Feuermann M., Pedruzzi I., Priebe S., Groth M., Winkler R., Li W.,
RA   Kniemeyer O., Schroeckh V., Hertweck C., Hube B., White T.C.,
RA   Platzer M., Guthke R., Heitman J., Woestemeyer J., Zipfel P.F.,
RA   Monod M., Brakhage A.A.;
RT   "Comparative and functional genomics provide insights into the
RT   pathogenicity of dermatophytic fungi.";
RL   Genome Biol. 12:R7.1-R7.16(2011).
CC   -!- CATALYTIC ACTIVITY: ATP + (deoxyribonucleotide)(n)-3'-hydroxyl +
CC       5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) +
CC       AMP + diphosphate. {ECO:0000256|RuleBase:RU000617}.
CC   -!- SIMILARITY: Belongs to the ATP-dependent DNA ligase family.
CC       {ECO:0000256|RuleBase:RU004196}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EFE42094.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; ACYE01000163; EFE42094.1; -; Genomic_DNA.
DR   RefSeq; XP_003022712.1; XM_003022666.1.
DR   STRING; 663202.XP_003022712.1; -.
DR   EnsemblFungi; EFE42094; EFE42094; TRV_03173.
DR   GeneID; 9581401; -.
DR   KEGG; tve:TRV_03173; -.
DR   eggNOG; KOG0966; Eukaryota.
DR   eggNOG; COG1793; LUCA.
DR   KO; K10777; -.
DR   OrthoDB; EOG092C18KW; -.
DR   Proteomes; UP000008383; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0071897; P:DNA biosynthetic process; IEA:InterPro.
DR   GO; GO:0051103; P:DNA ligation involved in DNA repair; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   CDD; cd00027; BRCT; 1.
DR   Gene3D; 1.10.3260.10; -; 1.
DR   Gene3D; 3.40.50.10190; -; 2.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR036420; BRCT_dom_sf.
DR   InterPro; IPR000977; DNA_ligase_ATP-dep.
DR   InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR   InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR   InterPro; IPR036599; DNA_ligase_N_sf.
DR   InterPro; IPR029710; LIG4.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   PANTHER; PTHR10459:SF7; PTHR10459:SF7; 1.
DR   Pfam; PF16589; BRCT_2; 1.
DR   Pfam; PF04679; DNA_ligase_A_C; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   Pfam; PF04675; DNA_ligase_A_N; 1.
DR   SUPFAM; SSF117018; SSF117018; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF52113; SSF52113; 2.
DR   TIGRFAMs; TIGR00574; dnl1; 1.
DR   PROSITE; PS50172; BRCT; 2.
DR   PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR   PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000617};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008383};
KW   DNA damage {ECO:0000256|RuleBase:RU000617};
KW   DNA recombination {ECO:0000256|RuleBase:RU000617};
KW   DNA repair {ECO:0000256|RuleBase:RU000617};
KW   DNA replication {ECO:0000256|RuleBase:RU000617};
KW   Ligase {ECO:0000256|RuleBase:RU000617};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000617}.
FT   DOMAIN      413    538       DNA_LIGASE_A3. {ECO:0000259|PROSITE:
FT                                PS50160}.
FT   DOMAIN      723    807       BRCT. {ECO:0000259|PROSITE:PS50172}.
FT   DOMAIN      885   1002       BRCT. {ECO:0000259|PROSITE:PS50172}.
SQ   SEQUENCE   1012 AA;  115468 MW;  8C5DA63BE81C4DC0 CRC64;
     MEPNPGGAIR ETERELDEKP RNHGQTLPFH DLFISLFNPL NDLKKKPAGP PAARRKAGPT
     GRNNLSPHEL RRNVIERFIS RWRQQVGNDF FPAFRLIVPE KDRDRAMYGL KEKAIGKLLV
     KVMKIDKNSE DGYNLLNWKL PGQRAATAMT GDFAGRCFEV ISKRPLRTEV GDMSIADVNS
     RLDDLAVASK EDAQLPILDE FYRRMNPEEM MWLIRIILRQ MKVGATERTF FEIWHPDAES
     LFNISSSLRR VCWELYLPSI RLEADEARVT LMQCFQPQLA QFQMHSFQKI IERMRLAEDD
     PEFWIEEKLD GERMQLHMET NSSIPGGKRF EFWSRKAKEY TYLYGNGFYD DNGSLTRHLK
     NAFADGVESI ILDGEMITWD PEQDAPVPFG TLKTAALAEQ RNPFSASGHR PLFRIFDIVY
     LNGKPLTRYT LRDRRRALEA SVIPVHRRFE IHPYEVGKSA SDIEPLLRKV VAEASEGLVL
     KNPNSPYRLN ERNDDWMKVK PDYMTEFGES LDCIVVGGYY GSGKRGGNIS SYLCGLRVDD
     THAEDGTNPM KCYSFCKVGG GFTAADYANI RHHTDGKWHD WNPKKPPTEY IELAGGDAQH
     ERPDVWIKPD DSVVVCVKAA AVTPSDQFRL GLTVRFPRFK RLRMDKDWQS ALSVQEFIDL
     KAGAEQEKKE KDFQVDNSRR KKTKRSKKKE LTVVGSGEPN VAYVGSKTHI FDGLSFCGLK
     IQALEVNYAD IPIVVMTESV KPMKKSKADL EQLIKANGGK IYQTNNAAKD TYCIADRRTV
     KVASLQKSGL ENVIRPCWIS DCISQNEHDT GESSILLPLE PRHMFFTKED QKEEISNNVD
     KYDDSFARDT NIAELTEILH KMDVISDISG EERLDIMSDL TLDGDQGWLF KNLTIFFAPC
     GHLSSVPGEP CVDGLSIRQQ LARNITTFTG ATVTDQQKNN RITHVIVDPS EDRDLETGKT
     KNYTTLRSEF ATRRTIPHFV TVQWVEECWK EKTLVDEERT YSMLAIALPG LC
//
DBGET integrated database retrieval system