ID   D4H4B7_DENA2            Unreviewed;       566 AA.
AC   D4H4B7;
DT   18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT   18-MAY-2010, sequence version 1.
DT   01-MAY-2013, entry version 18.
DE   SubName: Full=Nickel-dependent hydrogenase large subunit;
GN   OrderedLocusNames=Dacet_2486;
OS   Denitrovibrio acetiphilus (strain DSM 12809 / N2460).
OC   Bacteria; Deferribacteres; Deferribacterales; Deferribacteraceae;
OC   Denitrovibrio.
OX   NCBI_TaxID=522772;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 12809 / N2460;
RX   DOI=10.4056/sigs.892105;
RA   Kiss H., Lang E., Lapidus A., Copeland A., Nolan M.,
RA   Glavina Del Rio T., Chen F., Lucas S., Tice H., Cheng J., Han C.,
RA   Goodwin L., Pitluck S., Liolios K., Pati A., Ivanova N.,
RA   Mavromatis K., Chen A., Palaniappan K., Land M., Hauser L., Chang Y.,
RA   Jeffries C., Detter J., Brettin T., Spring S., Rohde M., Goker M.,
RA   Woyke T., Bristow J., Eisen J., Markowitz V., Hugenholtz P.,
RA   Kyrpides N., Klenk H.;
RT   "Complete genome sequence of Denitrovibrio acetiphilus type strain
RT   (N2460).";
RL   Stand. Genomic Sci. 2:270-279(2010).
CC   -!- SIMILARITY: Belongs to the [NiFe]/[NiFeSe] hydrogenase large
CC       subunit family.
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DR   EMBL; CP001968; ADD69246.1; -; Genomic_DNA.
DR   RefSeq; YP_003505202.1; NC_013943.1.
DR   EnsemblBacteria; ADD69246; ADD69246; Dacet_2486.
DR   GeneID; 8876858; -.
DR   KEGG; dap:Dacet_2486; -.
DR   PATRIC; 35354989; VBIDenAce54242_2491.
DR   HOGENOM; HOG000278800; -.
DR   KO; K06281; -.
DR   BioCyc; DACE522772:GHC2-2523-MONOMER; -.
DR   GO; GO:0008901; F:ferredoxin hydrogenase activity; IEA:InterPro.
DR   GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR   InterPro; IPR001501; Ni-dep_hyd_lsu.
DR   InterPro; IPR018194; Ni-dep_hyd_lsu_Ni_BS.
DR   Pfam; PF00374; NiFeSe_Hases; 1.
DR   PROSITE; PS00507; NI_HGENASE_L_1; 1.
DR   PROSITE; PS00508; NI_HGENASE_L_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Metal-binding; Nickel; Oxidoreductase.
SQ   SEQUENCE   566 AA;  62902 MW;  80D7BB61543DAF0A CRC64;
     MAERIVVDPI TRIEGHLRIE AKVENGKIVD AWSSGTMFRG IEKILNGRDP RDAWYITQRF
     CGVCTTVHSI ASIRAVENAL GIKVPYNAEL IRNIIMGSQY IQDHVVHFYH LHALDWVDIT
     SALQADPKKT AALQQSVSDW KYSSEDYFRG IQERIGAFVK TGRLGPFANA YWGHSAYKLP
     PEANLMATAH YLQALELQKE IIKIHAVLGS KNPHPQTFLV GGMAIPIDPN SQNAINADKI
     AMLLEYNKLA VEFVEQVYVP DILAVAPFYL DWAGIGAGHK NYMSYGEFPE TQLGYPNDMW
     LPSGIIKGGD LSNIIEVDQA KIAEDSAHAW YVDKSAKHPY DGSTERHYTG PKPPYDFLDV
     EKEYSYVKAP RYEGEPMEVG PLARMLVAYA KGHPEVKAVV DAVLGKLNAG PEVLFSTLGR
     TAARAIESLV TAKRVDKWIM DLATNIKSGD YQVHAGSKWE PSTWPSVAKG YGYHEAPRGA
     LGHWIVIKDG AIKNYQAVVP STWNAGPMDK GDVHGPYEQS LIGTPIADPD KPLEILRTIH
     SFDPCLACAV HLYDEKDKLR SKVKIL
//