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Database: UniProt/TrEMBL
Entry: D4HFH3_PROAS
LinkDB: D4HFH3_PROAS
Original site: D4HFH3_PROAS 
ID   D4HFH3_PROAS            Unreviewed;       502 AA.
AC   D4HFH3;
DT   18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT   18-MAY-2010, sequence version 1.
DT   25-OCT-2017, entry version 40.
DE   SubName: Full=Exo-alpha-sialidase {ECO:0000313|EMBL:ADD98985.1};
DE            EC=3.2.1.18 {ECO:0000313|EMBL:ADD98985.1};
GN   Name=nedA {ECO:0000313|EMBL:ADD98985.1};
GN   OrderedLocusNames=HMPREF0675_4627 {ECO:0000313|EMBL:ADD98985.1};
OS   Propionibacterium acnes (strain SK137).
OC   Bacteria; Actinobacteria; Propionibacteriales; Propionibacteriaceae;
OC   Cutibacterium.
OX   NCBI_TaxID=553199 {ECO:0000313|EMBL:ADD98985.1, ECO:0000313|Proteomes:UP000008987};
RN   [1] {ECO:0000313|Proteomes:UP000008987}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SK137 {ECO:0000313|Proteomes:UP000008987};
RA   Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B.,
RA   Sutton G.G., Nelson K.E.;
RT   "The complete genome of Propionibacterium acnes SK137.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP001977; ADD98985.1; -; Genomic_DNA.
DR   RefSeq; WP_002518458.1; NC_014039.1.
DR   CAZy; GH33; Glycoside Hydrolase Family 33.
DR   EnsemblBacteria; ADD98985; ADD98985; HMPREF0675_4627.
DR   KEGG; pak:HMPREF0675_4627; -.
DR   HOGENOM; HOG000141103; -.
DR   KO; K01186; -.
DR   OMA; GTEMFAP; -.
DR   Proteomes; UP000008987; Chromosome.
DR   GO; GO:0052794; F:exo-alpha-(2->3)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052795; F:exo-alpha-(2->6)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052796; F:exo-alpha-(2->8)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; PTHR10628; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; SSF50939; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008987};
KW   Glycosidase {ECO:0000313|EMBL:ADD98985.1};
KW   Hydrolase {ECO:0000313|EMBL:ADD98985.1};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     30       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        31    502       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003058611.
FT   DOMAIN      152    435       Sialidase. {ECO:0000259|Pfam:PF13088}.
SQ   SEQUENCE   502 AA;  53346 MW;  C639A6F6210685D0 CRC64;
     MTLTTKLSAL TTAGIMVVIG VPMVTQSAMA SGRAPAPVAA TTQPKLVTGD ITSTDQSGTN
     LFFGKKIVRN ARGAIMKVDR TWPAAVPAPL PDVRADSSTR MLLGPVVDLA VNEHPEGVFY
     RIPALATASN GDLLASYDLR PGSAGDAPNP NSIVQRRSRD NGRTWGPQTV IHAGTPGRRK
     VGYSDPSYLV DPATGRILNF HVKSYDRGFA TSEVGTDPDD RHVLHAEVST STDNGHTWTH
     RDITREITPD PTTRTRFVAS GQGIALLHGP HAGRLIAQMT VRNSVGQQAQ SIYSDDHGIT
     WHAGNPVGRM MDENKVVELS DGTLMLNSRD AARSGRRKVA YSQDGGLTWG PVKLVDDLID
     PTNNAQIIRA YPNARAGSAK ARILLFTNAR NATERVNGTL SVSCDDGRTW VSHQTYMPGE
     VGYTTAAVQS DGALGVLWER DGIRYSTIPM GWLNSVCPLA PSGRPTSGKP TSGTSLPPTA
     TPSGSLHGGA SSRPTSLPHT GD
//
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