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Database: UniProt/TrEMBL
Entry: D5B175_YERPZ
LinkDB: D5B175_YERPZ
Original site: D5B175_YERPZ 
ID   D5B175_YERPZ            Unreviewed;       292 AA.
AC   D5B175;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   26-NOV-2014, entry version 33.
DE   RecName: Full=Cysteine synthase {ECO:0000256|RuleBase:RU003985};
DE            EC=2.5.1.47 {ECO:0000256|RuleBase:RU003985};
GN   Name=cysM {ECO:0000313|EMBL:ADE65562.1};
GN   OrderedLocusNames=YPZ3_2652 {ECO:0000313|EMBL:ADE65562.1};
OS   Yersinia pestis (strain Z176003).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Yersinia.
OX   NCBI_TaxID=637386 {ECO:0000313|EMBL:ADE65562.1, ECO:0000313|Proteomes:UP000000932};
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Z176003;
RA   Hai R., Yu D., Xia L., Zhu X., Liang Y., Shen X., Zhang E., Zhang H.;
RT   "Complete genome sequence of Yersinia pestis from new plague natural
RT   foci in China.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADE65562.1, ECO:0000313|Proteomes:UP000000932}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Z176003 {ECO:0000313|EMBL:ADE65562.1,
RC   ECO:0000313|Proteomes:UP000000932};
RX   PubMed=20453098; DOI=10.1128/JB.00340-10;
RA   Shen X., Wang Q., Xia L., Zhu X., Zhang Z., Liang Y., Cai H.,
RA   Zhang E., Wei J., Chen C., Song Z., Zhang H., Yu D., Hai R.;
RT   "Complete genome sequences of Yersinia pestis from natural foci in
RT   China.";
RL   J. Bacteriol. 192:3551-3552(2010).
CC   -!- CATALYTIC ACTIVITY: O-acetyl-L-serine + hydrogen sulfide = L-
CC       cysteine + acetate. {ECO:0000256|RuleBase:RU003985}.
CC   -!- COFACTOR:
CC       Note=Pyridoxal phosphate. {ECO:0000256|RuleBase:RU003985};
CC   -!- SIMILARITY: Belongs to the cysteine synthase/cystathionine beta-
CC       synthase family. {ECO:0000256|RuleBase:RU003985}.
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DR   EMBL; CP001593; ADE65562.1; -; Genomic_DNA.
DR   RefSeq; YP_003568824.1; NC_014029.1.
DR   ProteinModelPortal; D5B175; -.
DR   EnsemblBacteria; ADE65562; ADE65562; YPZ3_2652.
DR   GeneID; 8992594; -.
DR   KEGG; ypz:YPZ3_2652; -.
DR   PATRIC; 35474038; VBIYerPes97410_3706.
DR   HOGENOM; HOG000217394; -.
DR   KO; K12339; -.
DR   OMA; IEQTIGN; -.
DR   BioCyc; YPES637386:GKE8-2705-MONOMER; -.
DR   GO; GO:0004124; F:cysteine synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
DR   InterPro; IPR005856; Cys_synthKM.
DR   InterPro; IPR005858; CysM.
DR   InterPro; IPR001216; P-phosphate_BS.
DR   InterPro; IPR001926; TrpB-like_PLP-dep.
DR   Pfam; PF00291; PALP; 1.
DR   SUPFAM; SSF53686; SSF53686; 1.
DR   TIGRFAMs; TIGR01136; cysKM; 1.
DR   TIGRFAMs; TIGR01138; cysM; 1.
DR   PROSITE; PS00901; CYS_SYNTHASE; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|RuleBase:RU003985};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000932};
KW   Cysteine biosynthesis {ECO:0000256|RuleBase:RU003985};
KW   Pyridoxal phosphate {ECO:0000256|RuleBase:RU003985};
KW   Transferase {ECO:0000256|RuleBase:RU003985}.
SQ   SEQUENCE   292 AA;  31279 MW;  569CDEA6B4BE6721 CRC64;
     MTTLEHCIGH TPLVKLQRLS QGLNAEIWVK LEGNNPAGSV KDRAALAMIQ QAELRGDIAP
     GDVLIEATSG NTGIALAMIA AMKGYHLKLL MPENMSQERQ AAMRAYGAEL ILVSREQGME
     GARDLALTMQ ENGEGNVLDQ FNNADNPYAH FTGTGPEIWQ QTAGKVSHFV SSMGTTGTIT
     GVSQYLKSQN PQVKVIGLQP AEGSSIPGIR RWSAEYIPGI FRPELVDQVL DITQSVAEQT
     MRRLAKEEGI FCGVSSGGAV AGALRIAADN PDAVIVAIIC DRGDRYLSTG VF
//
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