ID D5B5A4_YERPZ Unreviewed; 355 AA.
AC D5B5A4;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 01-MAY-2013, entry version 22.
DE RecName: Full=dTDP-glucose 4,6-dehydratase;
DE EC=4.2.1.46;
GN Name=rffG; OrderedLocusNames=YPZ3_3416;
OS Yersinia pestis (strain Z176003).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC Enterobacteriaceae; Yersinia.
OX NCBI_TaxID=637386;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Z176003;
RA Hai R., Yu D., Xia L., Zhu X., Liang Y., Shen X., Zhang E., Zhang H.;
RT "Complete genome sequence of Yersinia pestis from new plague natural
RT foci in China.";
RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Z176003;
RX PubMed=20453098; DOI=10.1128/JB.00340-10;
RA Shen X., Wang Q., Xia L., Zhu X., Zhang Z., Liang Y., Cai H.,
RA Zhang E., Wei J., Chen C., Song Z., Zhang H., Yu D., Hai R.;
RT "Complete genome sequences of Yersinia pestis from natural foci in
RT China.";
RL J. Bacteriol. 192:3551-3552(2010).
CC -!- CATALYTIC ACTIVITY: dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-
CC alpha-D-glucose + H(2)O.
CC -!- COFACTOR: NAD (By similarity).
CC -!- SIMILARITY: Belongs to the sugar epimerase family. dTDP-glucose
CC dehydratase subfamily.
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DR EMBL; CP001593; ADE66325.1; -; Genomic_DNA.
DR RefSeq; YP_003569587.1; NC_014029.1.
DR ProteinModelPortal; D5B5A4; -.
DR SMR; D5B5A4; 1-350.
DR EnsemblBacteria; ADE66325; ADE66325; YPZ3_3416.
DR GeneID; 8993388; -.
DR KEGG; ypz:YPZ3_3416; -.
DR PATRIC; 35476039; VBIYerPes97410_4674.
DR HOGENOM; HOG000168006; -.
DR KO; K01710; -.
DR OMA; ARSWWNT; -.
DR GO; GO:0050662; F:coenzyme binding; IEA:InterPro.
DR GO; GO:0008460; F:dTDP-glucose 4,6-dehydratase activity; IEA:EC.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0009225; P:nucleotide-sugar metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; -; 1.
DR InterPro; IPR005888; dTDP_Gluc_deHydtase.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR016040; NAD(P)-bd_dom.
DR PANTHER; PTHR10366:SF41; PTHR10366:SF41; 1.
DR Pfam; PF01370; Epimerase; 1.
DR TIGRFAMs; TIGR01181; dTDP_gluc_dehyt; 1.
PE 3: Inferred from homology;
KW Complete proteome; Lyase.
SQ SEQUENCE 355 AA; 39635 MW; 20EEBA276A4269FA CRC64;
MRRILVTGGA GFIGSAVVRH IIDGTSDSVV VVDKLTYAGN LESLSVVAGS ERYAFEQVDI
CDSSELDRVF AQYQPNVVMH LAAESHVDRS IDGPAAFIET NVVGTYTLLE AARHYWQQLS
VEAKQAFRFH HISTDEVYGD LHGTDDLFTE TTPYAPSSPY SASKASSDHL VRAWLRTYGL
PTLVTNCSNN YGPYHFPEKL IPLVILNALA GKPLPVYGNG AQVRDWLYVE DHARALYQVV
TEGVVGETYN IGGHNERKNI EVVETICALL DELVPAKPAG IAHYRDLITY VKDRPGHDMR
YAIDAGKIER ELGWRPQETF ESGIRKTVLW YLNNESWWRR VQDGSYAGER LGLSD
//
