ID D5C8U5_ENTCC Unreviewed; 308 AA.
AC D5C8U5;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 01-MAY-2013, entry version 20.
DE RecName: Full=Glutaminase;
DE EC=3.5.1.2;
GN Name=glsA; OrderedLocusNames=ECL_01990;
OS Enterobacter cloacae subsp. cloacae (strain ATCC 13047 / DSM 30054 /
OS NBRC 13535 / NCDC 279-56).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex.
OX NCBI_TaxID=716541;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13047 / DSM 30054 / NBRC 13535 / NCDC 279-56;
RX PubMed=20207761; DOI=10.1128/JB.00067-10;
RA Ren Y., Ren Y., Zhou Z., Guo X., Li Y., Feng L., Wang L.;
RT "Complete genome sequence of Enterobacter cloacae subsp. cloacae type
RT strain ATCC 13047.";
RL J. Bacteriol. 192:2463-2464(2010).
CC -!- CATALYTIC ACTIVITY: L-glutamine + H(2)O = L-glutamate + NH(3).
CC -!- SUBUNIT: Homotetramer (By similarity).
CC -!- SIMILARITY: Belongs to the glutaminase family.
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DR EMBL; CP001918; ADF61542.1; -; Genomic_DNA.
DR RefSeq; YP_003612491.1; NC_014121.1.
DR EnsemblBacteria; ADF61542; ADF61542; ECL_01990.
DR GeneID; 9124485; -.
DR KEGG; enc:ECL_01990; -.
DR PATRIC; 38454898; VBIEntClo148801_2189.
DR HOGENOM; HOG000216890; -.
DR KO; K01425; -.
DR BioCyc; ECLO716541:GH13-1974-MONOMER; -.
DR GO; GO:0004359; F:glutaminase activity; IEA:HAMAP.
DR GO; GO:0006541; P:glutamine metabolic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; -; 1.
DR HAMAP; MF_00313; Glutaminase; 1; -.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR015868; Glutaminase.
DR PANTHER; PTHR12544; PTHR12544; 1.
DR Pfam; PF04960; Glutaminase; 1.
DR SUPFAM; SSF56601; PBP_transp_fold; 1.
DR TIGRFAMs; TIGR03814; Gln_ase; 1.
PE 3: Inferred from homology;
KW Acetylation; Complete proteome; Hydrolase.
FT BINDING 66 66 Substrate (By similarity).
FT BINDING 117 117 Substrate (By similarity).
FT BINDING 161 161 Substrate (By similarity).
FT BINDING 168 168 Substrate (By similarity).
FT BINDING 192 192 Substrate (By similarity).
FT BINDING 244 244 Substrate (By similarity).
FT BINDING 262 262 Substrate; via amide nitrogen (By
FT similarity).
SQ SEQUENCE 308 AA; 33681 MW; 78A125B367CFF806 CRC64;
MAAVIHNEML DEILAQVRPL LGKGKVADYI PALASVSGNK LGIAICTIDG QRYQAGDATE
RFSIQSISKV LSLVAAMRQY EEEEIWQRVG KDPSGQPFNS LLQLEIEQGK PRNPFINAGA
LVVCDMLQSR LSAPRQRMLE IVRQLSGVDD IAYDSVVARS EFEHSARNAA IAWLMKSFGN
FHNDVATVLQ NYFHYCALKM SCVELAQTFL FLAHQGHAPH LDQEVVSPMQ ARQVNALMAT
SGMYQNAGEF AWRVGLPAKS GVGGGVVAIV PHEMAIAVWS PELDETGNSL AGVAVLEKLT
QRLGRSVY
//
