ID   D5T3S7_LEUKI            Unreviewed;       214 AA.
AC   D5T3S7;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   01-MAY-2013, entry version 15.
DE   RecName: Full=Thymidylate kinase;
DE            EC=2.7.4.9;
DE   AltName: Full=dTMP kinase;
GN   Name=tmk; OrderedLocusNames=LKI_06935;
OS   Leuconostoc kimchii (strain IMSNU 11154 / KCTC 2386 / IH25).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Leuconostoc.
OX   NCBI_TaxID=762051;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IMSNU 11154 / KCTC 2386 / IH25;
RX   PubMed=20494991; DOI=10.1128/JB.00508-10;
RA   Oh H.M., Cho Y.J., Kim B.K., Roe J.H., Kang S.O., Nahm B.H., Jeong G.,
RA   Han H.U., Chun J.;
RT   "Complete genome sequence analysis of Leuconostoc kimchii IMSNU
RT   11154.";
RL   J. Bacteriol. 192:3844-3845(2010).
CC   -!- FUNCTION: Phosphorylation of dTMP to form dTDP in both de novo and
CC       salvage pathways of dTTP synthesis (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + dTMP = ADP + dTDP.
CC   -!- SIMILARITY: Belongs to the thymidylate kinase family.
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DR   EMBL; CP001758; ADG40926.1; -; Genomic_DNA.
DR   RefSeq; YP_003621895.1; NC_014136.1.
DR   EnsemblBacteria; ADG40926; ADG40926; LKI_06935.
DR   GeneID; 9133964; -.
DR   KEGG; lki:LKI_06935; -.
DR   PATRIC; 38187394; VBILeuKim161478_1359.
DR   HOGENOM; HOG000229078; -.
DR   KO; K00943; -.
DR   BioCyc; LKIM762051:GJOL-1452-MONOMER; -.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0004798; F:thymidylate kinase activity; IEA:HAMAP.
DR   GO; GO:0006233; P:dTDP biosynthetic process; IEA:InterPro.
DR   GO; GO:0006235; P:dTTP biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00165; Thymidylate_kinase; 1; -.
DR   InterPro; IPR018095; Thymidylate_kin_CS.
DR   InterPro; IPR018094; Thymidylate_kinase.
DR   PANTHER; PTHR10344; PTHR10344; 1.
DR   TIGRFAMs; TIGR00041; DTMP_kinase; 1.
DR   PROSITE; PS01331; THYMIDYLATE_KINASE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Kinase; Nucleotide biosynthesis;
KW   Nucleotide-binding; Transferase.
FT   NP_BIND      11     18       ATP (By similarity).
SQ   SEQUENCE   214 AA;  23938 MW;  C6159152C29918F2 CRC64;
     MTKPLFITFE GPEGAGKTSV LNQLVAEFQQ TLGDDLISTR EPGGNPISEA IRAILQPEED
     NGMDDRTEAL LYTAARRQHL VETVLPALKA GKVVISDRYV DSSLAYQGGG RGLGVDHIWQ
     INQFAIDGLL PDLTIYFDLP SELGLARVKA NRQGKIDRLD KESLAFHQKV RKTYLELQVK
     FSDRIKIVDA TQSLDNVVDA TRQLILERMK YREV
//