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Database: UniProt/TrEMBL
Entry: D7BHV4_MEISD
LinkDB: D7BHV4_MEISD
Original site: D7BHV4_MEISD 
ID   D7BHV4_MEISD            Unreviewed;       507 AA.
AC   D7BHV4;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   19-FEB-2014, entry version 23.
DE   RecName: Full=Glycine--tRNA ligase;
DE            EC=6.1.1.14;
DE   AltName: Full=Glycyl-tRNA synthetase;
GN   Name=glyQS; OrderedLocusNames=Mesil_2174;
OS   Meiothermus silvanus (strain ATCC 700542 / DSM 9946 / VI-R2) (Thermus
OS   silvanus).
OC   Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae;
OC   Meiothermus.
OX   NCBI_TaxID=526227;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700542 / DSM 9946 / VI-R2;
RX   DOI=10.4056/sigs.1042812;
RA   Sikorski J., Tindall B., Lowry S., Lucas S., Nolan M., Copeland A.,
RA   Glavina Del Rio T., Tice H., Cheng J., Han C., Pitluck S., Liolios K.,
RA   Ivanova N., Mavromatis K., Mikhailova N., Pati A., Goodwin L.,
RA   Chen A., Palaniappan K., Land M., Hauser L., Chang Y., Jeffries C.,
RA   Rohde M., Goker M., Woyke T., Bristow J., Eisen J., Markowitz V.,
RA   Hugenholtz P., Kyrpides N., Klenk H., Lapidus A.;
RT   "Complete genome sequence of Meiothermus silvanus type strain (VI-
RT   R2).";
RL   Stand. Genomic Sci. 3:37-46(2010).
CC   -!- FUNCTION: Catalyzes the attachment of glycine to tRNA(Gly) (By
CC       similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + glycine + tRNA(Gly) = AMP + diphosphate
CC       + glycyl-tRNA(Gly).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase
CC       family.
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DR   EMBL; CP002042; ADH64044.1; -; Genomic_DNA.
DR   RefSeq; YP_003685552.1; NC_014212.1.
DR   EnsemblBacteria; ADH64044; ADH64044; Mesil_2174.
DR   GeneID; 9251688; -.
DR   KEGG; msv:Mesil_2174; -.
DR   PATRIC; 38193157; VBIMeiSil18825_2216.
DR   HOGENOM; HOG000242016; -.
DR   KO; K01880; -.
DR   OMA; DIEFEFP; -.
DR   BioCyc; MSIL526227:GJ9Q-2213-MONOMER; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0004820; F:glycine-tRNA ligase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006426; P:glycyl-tRNA aminoacylation; IEA:UniProtKB-HAMAP.
DR   Gene3D; 3.40.50.800; -; 1.
DR   HAMAP; MF_00253_B; Gly_tRNA_synth_B; 1.
DR   InterPro; IPR002314; aa-tRNA-synt_IIb_cons-dom.
DR   InterPro; IPR006195; aa-tRNA-synth_II.
DR   InterPro; IPR004154; Anticodon-bd.
DR   InterPro; IPR027031; Gly-tRNA_synthase/POLG2.
DR   InterPro; IPR022961; Gly_tRNA_ligase_bac.
DR   InterPro; IPR002315; tRNA-synt_gly.
DR   PANTHER; PTHR10745; PTHR10745; 1.
DR   Pfam; PF03129; HGTP_anticodon; 1.
DR   Pfam; PF00587; tRNA-synt_2b; 1.
DR   PRINTS; PR01043; TRNASYNTHGLY.
DR   SUPFAM; SSF52954; SSF52954; 1.
DR   TIGRFAMs; TIGR00389; glyS_dimeric; 1.
DR   PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Cytoplasm;
KW   Ligase; Nucleotide-binding; Protein biosynthesis.
FT   NP_BIND     222    224       ATP (By similarity).
FT   NP_BIND     232    237       ATP (By similarity).
FT   NP_BIND     307    308       ATP (By similarity).
FT   NP_BIND     366    369       ATP (By similarity).
FT   REGION      237    241       Substrate binding (By similarity).
FT   REGION      362    366       Substrate binding (By similarity).
FT   BINDING      99     99       Substrate (By similarity).
FT   BINDING     190    190       Substrate (By similarity).
SQ   SEQUENCE   507 AA;  57458 MW;  E15FD5E05CC3A941 CRC64;
     MPAETMDELV SLCKRRGFIF QGSEIYGGLQ GTYDYGPLGV ELKNNLKAAW WRANVYERDD
     MEGLDASILT HRLVLHYSGH EATFADPLID NRISKKRYRL DHLLKEQKPG VCAAVAVGMG
     LEPNTDIATL VAALMADPER AAQAMNAARV VDPADGAPGD WTPPRPFNMM FKTTIGPVAD
     EDSYGYLRPE TAQGIFVNFK NVLDSTSRRL PFGIAQIGKA FRNEITPRNF IFRVREFEQM
     EIEYFVKPGT DEHWHQHWLE TRLEWWEAQG IPRAQIQVLD VPKEDLAHYS KRTYDLLYNF
     PTLGFEEIEG IANRSDYDLG SHTKAQSELG IQARVMENTD STAKLAIQDP ETGKWIVPFV
     IEPSAGVDRG VLAVLSEAYT REKLESGEER IVLKLKPHLA PIKVAVIPLA KNKEEITRYA
     KDLKRKLQAL GMGRVLYEDT GNIGKAYRRH DEVGTPFCVT VDYDTIGKSQ DGSTTLMDTV
     TVRDRDTMQQ ERVHVKELPQ YLQERLR
//
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