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Database: UniProt/TrEMBL
Entry: D7CHE7_STRBB
LinkDB: D7CHE7_STRBB
Original site: D7CHE7_STRBB 
ID   D7CHE7_STRBB            Unreviewed;      1276 AA.
AC   D7CHE7;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   07-JUN-2017, entry version 45.
DE   SubName: Full=Alpha-ketoglutarate decarboxylase {ECO:0000313|EMBL:ADI07004.1};
DE            EC=4.1.1.71 {ECO:0000313|EMBL:ADI07004.1};
GN   Name=kgd {ECO:0000313|EMBL:ADI07004.1};
GN   OrderedLocusNames=SBI_03883 {ECO:0000313|EMBL:ADI07004.1};
OS   Streptomyces bingchenggensis (strain BCW-1).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=749414 {ECO:0000313|EMBL:ADI07004.1, ECO:0000313|Proteomes:UP000000377};
RN   [1] {ECO:0000313|EMBL:ADI07004.1, ECO:0000313|Proteomes:UP000000377}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BCW-1 {ECO:0000313|EMBL:ADI07004.1,
RC   ECO:0000313|Proteomes:UP000000377};
RX   PubMed=20581206; DOI=10.1128/JB.00596-10;
RA   Wang X.J., Yan Y.J., Zhang B., An J., Wang J.J., Tian J., Jiang L.,
RA   Chen Y.H., Huang S.X., Yin M., Zhang J., Gao A.L., Liu C.X., Zhu Z.X.,
RA   Xiang W.S.;
RT   "Genome sequence of the milbemycin-producing bacterium Streptomyces
RT   bingchenggensis.";
RL   J. Bacteriol. 192:4526-4527(2010).
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DR   EMBL; CP002047; ADI07004.1; -; Genomic_DNA.
DR   RefSeq; WP_014176478.1; NC_016582.1.
DR   STRING; 749414.SBI_03883; -.
DR   EnsemblBacteria; ADI07004; ADI07004; SBI_03883.
DR   KEGG; sbh:SBI_03883; -.
DR   PATRIC; fig|749414.3.peg.4021; -.
DR   eggNOG; ENOG4105C7P; Bacteria.
DR   eggNOG; COG0508; LUCA.
DR   eggNOG; COG0567; LUCA.
DR   HOGENOM; HOG000259587; -.
DR   KO; K00164; -.
DR   OMA; IDMVCYR; -.
DR   OrthoDB; POG091H03SK; -.
DR   Proteomes; UP000000377; Chromosome.
DR   GO; GO:0008683; F:2-oxoglutarate decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:InterPro.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:InterPro.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR   InterPro; IPR032106; 2-oxogl_dehyd_N.
DR   InterPro; IPR011603; 2oxoglutarate_DH_E1.
DR   InterPro; IPR001017; DH_E1.
DR   InterPro; IPR031717; KGD_C.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   PANTHER; PTHR23152; PTHR23152; 1.
DR   Pfam; PF00198; 2-oxoacid_dh; 1.
DR   Pfam; PF16078; 2-oxogl_dehyd_N; 1.
DR   Pfam; PF00676; E1_dh; 1.
DR   Pfam; PF16870; OxoGdeHyase_C; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   PIRSF; PIRSF000157; Oxoglu_dh_E1; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; SSF52518; 2.
DR   TIGRFAMs; TIGR00239; 2oxo_dh_E1; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000377};
KW   Lyase {ECO:0000313|EMBL:ADI07004.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000377}.
FT   DOMAIN      928   1121       Transket_pyr. {ECO:0000259|SMART:
FT                                SM00861}.
SQ   SEQUENCE   1276 AA;  139461 MW;  258C24D7E0667122 CRC64;
     MSPQSPNSSS VSTDQQDGQG SNPAAAFGPN EWLVDEIYQQ YLQDPNSVDR AWWDFFADYK
     PGQDTSSAVA ESAPAPAAGG AAGTGAAAPA PVSNGAAPAP VKPAAPAVPP AAQQAAPAPA
     PVKPAAPAPA AAPAKAAPAA KTAPAKAAEP AAPGAGPEYV TLRGPSAAVA KNMNASLQLP
     TATSVRAVPV KLLFDNRIVI NNHLKRARGG KVSFTHLIGY AMVQALKAMP SMNHSFTEKD
     GKPTLVKPEH INLGLAIDLV KPNGDRQLVV AAIKKAETLN FFEFWQAYED IVRRARANKL
     TMEDFTGVTA SLTNPGGIGT VHSVPRLMPG QGLIIGVGAM EYPAEFQGTS QDTLNKLGIA
     KVMTLTSTYD HRVIQGAASG EFLRIMSQLL LGENDFYDEI FKALRIPYEP VRWLRDIDVS
     HDDDVTKAAR VFDLIHSYRV RGHVMADTDP LEYRQRKHPD LDIIEHGLTL WDLEREFAVG
     GFAGKTMMNL RDILGVLRDS YCRTTGIEFM HIQDPKQRKW IQDRVERPHA KPERDEQLRI
     LRRLNAAEAF ETFLQTKYVG QKRFSLEGGE SVIPLLDAVL DAAAESRLDE VVIGMAHRGR
     LNVLANIVGK SYAQIFREFE GNLDPKSMHG SGDVKYHLGA EGTFTGLDGE QIAVSLTANP
     SHLEAVDPVL EGVVRAKQDI IGKAGTDFTV LPVALHGDAA FAGQGVVAET LNMSQLRGYR
     TGGTVHIVIN NQVGFTAAPA ASRSSMYATD VARMIEAPIF HVNGDDPEAV VRVARLAFEF
     RQAFNKDVVI DLICYRRRGH NETDNPGFTQ PLMYDLIDKK RSVRKLYTES LIGRGDITLE
     EAEQALQDFQ GQLEKVFTEV RDATSQPTPT AVPEPQPEFP VAVSTAVSQE IVKRIAESQV
     NIPDRITVHP RLYPQLQRRA AMIEDDTIDW GMGETLAIGS LLMEGTPVRL AGQDSRRGTF
     GQRHAVLVDR ETGEDYTPLL YLTDEQARYN VYDSLLSEYA AMGFEYGYSL ARPDALVMWE
     AQFGDFVNGA QTIVDEFISS AEQKWGQTSG VTLLLPHGYE GQGPDHSSAR IERFLQLCGQ
     NNMTVAAPTL PSNYFHLLRW QVHNPHHKPL VVFTPKSMLR LKAAASKTEE FLNGSFRPVI
     GDETVDPAAV RKVVFTSGKV YYDLAAERDK RGLTDTAIIR LERLYPLPGA ELQAEIAKYS
     GVQKFVWAQE EPANQGAWPF VALNLIDHLE LSVGADLPAS ERLVRVSRPH SSSPAVGSNK
     RHQAEQQALV NEVLEI
//
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