GenomeNet

Database: UniProt/TrEMBL
Entry: D7D332_GEOSC
LinkDB: D7D332_GEOSC
Original site: D7D332_GEOSC 
ID   D7D332_GEOSC            Unreviewed;       307 AA.
AC   D7D332;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   16-OCT-2013, entry version 26.
DE   RecName: Full=2-dehydropantoate 2-reductase;
DE            EC=1.1.1.169;
GN   OrderedLocusNames=GC56T3_2948;
OS   Geobacillus sp. (strain C56-T3).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus.
OX   NCBI_TaxID=691437;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C56-T3;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Kourtz L., Brumm P., Mead D.,
RA   Woyke T.;
RT   "Complete sequence of Geobacillus sp. C56-T3.";
RL   Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the NADPH-dependent reduction of ketopantoate
CC       into pantoic acid (By similarity).
CC   -!- CATALYTIC ACTIVITY: (R)-pantoate + NADP(+) = 2-dehydropantoate +
CC       NADPH.
CC   -!- SIMILARITY: Belongs to the ketopantoate reductase family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP002050; ADI27889.1; -; Genomic_DNA.
DR   RefSeq; YP_003672466.1; NC_014206.1.
DR   ProteinModelPortal; D7D332; -.
DR   EnsemblBacteria; ADI27889; ADI27889; GC56T3_2948.
DR   GeneID; 9238046; -.
DR   KEGG; gct:GC56T3_2948; -.
DR   PATRIC; 38173130; VBIGeoSp154431_3200.
DR   HOGENOM; HOG000050222; -.
DR   KO; K00077; -.
DR   BioCyc; GSP691437:GI2V-3040-MONOMER; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0008677; F:2-dehydropantoate 2-reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0015940; P:pantothenate biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1040.10; -; 1.
DR   Gene3D; 3.40.50.720; -; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH_C-like.
DR   InterPro; IPR003710; ApbA.
DR   InterPro; IPR013752; ApbA_C.
DR   InterPro; IPR013332; ApbA_N.
DR   InterPro; IPR013328; DH_multihelical.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Pfam; PF02558; ApbA; 1.
DR   Pfam; PF08546; ApbA_C; 1.
DR   SUPFAM; SSF48179; SSF48179; 1.
DR   TIGRFAMs; TIGR00745; apbA_panE; 1.
PE   3: Inferred from homology;
KW   Complete proteome; NADP; Oxidoreductase; Pantothenate biosynthesis.
SQ   SEQUENCE   307 AA;  34016 MW;  976F3B6D6628FA6B CRC64;
     MRILFVGAGA VGGYFGGRLL EKGVDVTFLV RERRKQELEK YGLVIHSIHG DAVLAPKLLV
     AGESAEPFDL VVFSNKAYHL DGAIADAKPY VGEATMILPL LNGMAHMEAL WKAFGRENVL
     GGLCFIETTL NERGEIIQTS PAHEMRFGEW PNGRSERTEV LASLFAGANA CFRLSEQIAA
     DMWNKYLFIA TMSGVTTLFR APIGPIRSGE YGSVIIDRLF REIKTIIQAH GAPLTDEMAE
     RQRTQLEQIA PTMKSSMQRD MEKGQLIEAD HLQGYLLALA KRHGIHAPML EAVYHNLKIY
     EASRATS
//
DBGET integrated database retrieval system