GenomeNet

Database: UniProt/TrEMBL
Entry: D7MMS2_ARALL
LinkDB: D7MMS2_ARALL
Original site: D7MMS2_ARALL 
ID   D7MMS2_ARALL            Unreviewed;      1221 AA.
AC   D7MMS2;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   25-OCT-2017, entry version 54.
DE   RecName: Full=DNA ligase {ECO:0000256|RuleBase:RU000617};
DE            EC=6.5.1.1 {ECO:0000256|RuleBase:RU000617};
GN   ORFNames=ARALYDRAFT_495812 {ECO:0000313|EMBL:EFH42446.1};
OS   Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
OC   Arabidopsis.
OX   NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN   [1] {ECO:0000313|Proteomes:UP000008694}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX   PubMed=21478890; DOI=10.1038/ng.807;
RA   Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA   Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA   Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A.,
RA   Schneeberger K., Spannagl M., Wang X., Yang L., Nasrallah M.E.,
RA   Bergelson J., Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X.,
RA   Van de Peer Y., Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT   "The Arabidopsis lyrata genome sequence and the basis of rapid genome
RT   size change.";
RL   Nat. Genet. 43:476-481(2011).
CC   -!- CATALYTIC ACTIVITY: ATP + (deoxyribonucleotide)(n)-3'-hydroxyl +
CC       5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) +
CC       AMP + diphosphate. {ECO:0000256|RuleBase:RU000617}.
CC   -!- SIMILARITY: Belongs to the ATP-dependent DNA ligase family.
CC       {ECO:0000256|RuleBase:RU004196}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; GL348720; EFH42446.1; -; Genomic_DNA.
DR   RefSeq; XP_002866187.1; XM_002866141.1.
DR   ProteinModelPortal; D7MMS2; -.
DR   STRING; 59689.fgenesh2_kg.8__1628__AT5G57160.1; -.
DR   EnsemblPlants; fgenesh2_kg.8__1628__AT5G57160.1; fgenesh2_kg.8__1628__AT5G57160.1; fgenesh2_kg.8__1628__AT5G57160.1.
DR   Gramene; fgenesh2_kg.8__1628__AT5G57160.1; fgenesh2_kg.8__1628__AT5G57160.1; fgenesh2_kg.8__1628__AT5G57160.1.
DR   KEGG; aly:ARALYDRAFT_495812; -.
DR   KO; K10777; -.
DR   OrthoDB; EOG093600VG; -.
DR   Proteomes; UP000008694; Unassembled WGS sequence.
DR   GO; GO:0048046; C:apoplast; IEA:EnsemblPlants.
DR   GO; GO:0009506; C:plasmodesma; IEA:EnsemblPlants.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0071897; P:DNA biosynthetic process; IEA:InterPro.
DR   GO; GO:0051103; P:DNA ligation involved in DNA repair; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:EnsemblPlants.
DR   GO; GO:0010165; P:response to X-ray; IEA:EnsemblPlants.
DR   CDD; cd00027; BRCT; 1.
DR   Gene3D; 1.10.3260.10; -; 1.
DR   Gene3D; 3.40.50.10190; -; 2.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR036420; BRCT_dom_sf.
DR   InterPro; IPR000977; DNA_ligase_ATP-dep.
DR   InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR   InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR   InterPro; IPR036599; DNA_ligase_N_sf.
DR   InterPro; IPR029710; LIG4.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   PANTHER; PTHR10459:SF7; PTHR10459:SF7; 2.
DR   Pfam; PF16589; BRCT_2; 1.
DR   Pfam; PF04679; DNA_ligase_A_C; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   Pfam; PF04675; DNA_ligase_A_N; 1.
DR   SMART; SM00292; BRCT; 2.
DR   SUPFAM; SSF117018; SSF117018; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF52113; SSF52113; 2.
DR   TIGRFAMs; TIGR00574; dnl1; 1.
DR   PROSITE; PS50172; BRCT; 2.
DR   PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR   PROSITE; PS00333; DNA_LIGASE_A2; 1.
DR   PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000617};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008694};
KW   DNA damage {ECO:0000256|RuleBase:RU000617};
KW   DNA recombination {ECO:0000256|RuleBase:RU000617};
KW   DNA repair {ECO:0000256|RuleBase:RU000617};
KW   DNA replication {ECO:0000256|RuleBase:RU000617};
KW   Ligase {ECO:0000256|RuleBase:RU000617};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000617};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008694}.
FT   DOMAIN      338    481       DNA_LIGASE_A3. {ECO:0000259|PROSITE:
FT                                PS50160}.
FT   DOMAIN      653    741       BRCT. {ECO:0000259|PROSITE:PS50172}.
FT   DOMAIN      841    911       BRCT. {ECO:0000259|PROSITE:PS50172}.
SQ   SEQUENCE   1221 AA;  137969 MW;  D5E1EFEA90E6A8C1 CRC64;
     MTEEIKFSVL VSLFNWIQKS KTSSQKRSKF RKFLDTYCKP SDYFVAVRLI IPSLDRERGS
     YGLKESVLAT CLIDALGISR DAPDAVRLLN WRKGGTAKAG ANAGNFSLIA AEVLQRRQGM
     ASGGLTVKEL NDLLDRLASS ENRCRAEKTL VLSTLIQKTN AQEMKWVIRI ILKDLKLGMS
     EKSIFQEFHP DAEDLFNVTC DLKLVCEKLR DRHQRHKRQD IEVGKAVRPQ LAMRISDVNA
     AWKKLHGKDV VAECKFDGDR IQIHKNGTDI HYFSRNFLDH SEYAHAMSDL IVQNILVDKC
     ILDGEMLVWD TSLNRFAEFG SNQEIAKAAR EGLDSHKQLC YVAFDVLYVG DTSVIHQSLK
     ERHELLRKVV KPLKGRLEVL VPEGGLNVHR PSGEPSWSIV VHAAADVERF FKETVENRDE
     GVVLKDLGSK WEPGDRSGKW LKLKPEYIRA GTDLDVLIIG GYYGSGRRGG EVAQFLVALA
     DRAEANVYPR RFMSFCRVGT GLSDDELNTV VSKLKPYFRK NEHPKKAPPS FYQVTNHSKE
     RPDVWIESPE KSIILSITSD IRTIRSEVFV APYSLRFPRI DKVRYDKSWH ECLDVQAFVE
     LVNSSNGTTQ KQKESESTQD NPKVNKSSKK GEKKNVSLVP SQFIQTDVSD IKGKTSVFSN
     MIFYFVNVPL SHSLETFHKT VVENGGKFSM NLNNSVTHCI AAESSGIKYQ AAKRQRDVIH
     FSWVLDCCSR NKMLPLQPKY FLHLTDASRT KLQDDIDEFS DSYYWDLDLE GLKQVLSNAK
     QSEDSKSIDY YKKKLCPEKR WSCLFSCCVY FYPYSQTLST EEEALLGIMA KRLALEVLMG
     GGKVSNNLAH ASHLVVLTMA EKSLDFASVS KSFSEMEKRL LLKKRLHVVS SRWLEDSLQR
     EEKLCEDVYN LRPKYMEESD TEESDKSEHD TTEVASEGSA QTEEPSSSKM TITSSRGRST
     TRAVKRGRSS TNSLQRVQRR RGKQPSKITG DETEESDAAE EKVSTRLSDI AEETDSFGEA
     QRNSSRGRSA KRGKSRVGQT QRVQRSRRGK KPSKIGGDES EENDEFGDKN NVSSDAQESN
     AAGRSVENEE TREPDIAKYT ESLQRDNTAA VEDASQDSKN AKTEMDMKEK LKIHEDPLQA
     MLMNMFPSLS QKNTETSNRI TGENRKANVS GECESSEKRK LDAETDSTCV NAGTDSEAVP
     PLVKKKKVSY RDVAGELLKD W
//
DBGET integrated database retrieval system