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Database: UniProt/TrEMBL
Entry: D8K716_NITWC
LinkDB: D8K716_NITWC
Original site: D8K716_NITWC 
ID   D8K716_NITWC            Unreviewed;       188 AA.
AC   D8K716;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   29-OCT-2014, entry version 23.
DE   RecName: Full=Deoxycytidine triphosphate deaminase {ECO:0000256|HAMAP-Rule:MF_00146};
DE            Short=dCTP deaminase {ECO:0000256|HAMAP-Rule:MF_00146};
DE            EC=3.5.4.13 {ECO:0000256|HAMAP-Rule:MF_00146};
GN   Name=dcd {ECO:0000256|HAMAP-Rule:MF_00146};
GN   OrderedLocusNames=Nwat_1842 {ECO:0000313|EMBL:ADJ28693.1};
OS   Nitrosococcus watsoni (strain C-113).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Chromatiales;
OC   Chromatiaceae; Nitrosococcus.
OX   NCBI_TaxID=105559 {ECO:0000313|EMBL:ADJ28693.1, ECO:0000313|Proteomes:UP000000393};
RN   [1] {ECO:0000313|EMBL:ADJ28693.1, ECO:0000313|Proteomes:UP000000393}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C-113 {ECO:0000313|EMBL:ADJ28693.1,
RC   ECO:0000313|Proteomes:UP000000393};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Malfatti S.A., Chain P.S.G., Land M., Hauser L.,
RA   Kyrpides N., Ivanova N., Cambell M.A., Heidelberg J.F., Klotz M.G.,
RA   Woyke T.;
RT   "Complete sequence of chromosome of Nitrosococcus watsoni C-113.";
RL   Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: dCTP + H(2)O = dUTP + NH(3).
CC       {ECO:0000256|HAMAP-Rule:MF_00146, ECO:0000256|SAAS:SAAS00054764}.
CC   -!- PATHWAY: Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP
CC       (dUTP route): step 1/2. {ECO:0000256|HAMAP-Rule:MF_00146,
CC       ECO:0000256|SAAS:SAAS00054724}.
CC   -!- SIMILARITY: Belongs to the dCTP deaminase family.
CC       {ECO:0000256|HAMAP-Rule:MF_00146}.
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DR   EMBL; CP002086; ADJ28693.1; -; Genomic_DNA.
DR   RefSeq; YP_003761014.1; NC_014315.1.
DR   ProteinModelPortal; D8K716; -.
DR   EnsemblBacteria; ADJ28693; ADJ28693; Nwat_1842.
DR   GeneID; 9393327; -.
DR   KEGG; nwa:Nwat_1842; -.
DR   PATRIC; 42236270; VBINitWat28885_1998.
DR   KO; K01494; -.
DR   OMA; EFEGHIT; -.
DR   BioCyc; NWAT105559:GHXU-1879-MONOMER; -.
DR   UniPathway; UPA00610; UER00665.
DR   GO; GO:0008829; F:dCTP deaminase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006226; P:dUMP biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006229; P:dUTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0009220; P:pyrimidine ribonucleotide biosynthetic process; IEA:UniProtKB-HAMAP.
DR   Gene3D; 2.70.40.10; -; 1.
DR   HAMAP; MF_00146; dCTP_deaminase; 1.
DR   InterPro; IPR011962; dCTP_deam.
DR   InterPro; IPR029054; dUTPase-like.
DR   InterPro; IPR008180; dUTPase/dCTP_deaminase.
DR   Pfam; PF00692; dUTPase; 1.
DR   SUPFAM; SSF51283; SSF51283; 1.
DR   TIGRFAMs; TIGR02274; dCTP_deam; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000393};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_00146,
KW   ECO:0000256|SAAS:SAAS00054748};
KW   Nucleotide metabolism {ECO:0000256|HAMAP-Rule:MF_00146,
KW   ECO:0000256|SAAS:SAAS00054734}.
SQ   SEQUENCE   188 AA;  21191 MW;  9E4B57E0C4BBD846 CRC64;
     MSIKSDKWIR HMAREHGIIE PFEPRQIREA NNARIISYGT SSYGYDIRCS NEFKIFTNIN
     SAIVDPKNFD ASSFVDVQSD VCIIPPNSFA LARTVEYFRI PRSVLTICLG KSTYARCGII
     VNITPLEPEW EGYVTLEFSN TTPLPAKVYA NEGVAQVVFF ESDELCETSY RDRGGKYQGQ
     IGVTLPKA
//
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