ID D8K7I2_NITWC Unreviewed; 461 AA.
AC D8K7I2;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 01-MAY-2013, entry version 19.
DE RecName: Full=Nicotinate phosphoribosyltransferase;
DE EC=2.4.2.11;
GN OrderedLocusNames=Nwat_2025;
OS Nitrosococcus watsoni (strain C-113).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Chromatiales;
OC Chromatiaceae; Nitrosococcus.
OX NCBI_TaxID=105559;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C-113;
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Malfatti S.A., Chain P.S.G., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Cambell M.A., Heidelberg J.F., Klotz M.G.,
RA Woyke T.;
RT "Complete sequence of chromosome of Nitrosococcus watsoni C-113.";
RL Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY: Beta-nicotinate D-ribonucleotide + diphosphate
CC = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate.
CC -!- CATALYTIC ACTIVITY: Nicotinate D-ribonucleotide + diphosphate =
CC nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate.
CC -!- PATHWAY: Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-
CC ribonucleotide from nicotinate: step 1/1.
CC -!- SIMILARITY: Belongs to the NAPRTase family.
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DR EMBL; CP002086; ADJ28859.1; -; Genomic_DNA.
DR RefSeq; YP_003761180.1; NC_014315.1.
DR ProteinModelPortal; D8K7I2; -.
DR EnsemblBacteria; ADJ28859; ADJ28859; Nwat_2025.
DR GeneID; 9393513; -.
DR KEGG; nwa:Nwat_2025; -.
DR PATRIC; 42236661; VBINitWat28885_2190.
DR KO; K00763; -.
DR BioCyc; NWAT105559:GHXU-2116-MONOMER; -.
DR UniPathway; UPA00253; UER00457.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0004516; F:nicotinate phosphoribosyltransferase activity; IEA:EC.
DR GO; GO:0004514; F:nicotinate-nucleotide diphosphorylase (carboxylating) activity; IEA:InterPro.
DR GO; GO:0009435; P:NAD biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0019358; P:nicotinate nucleotide salvage; IEA:InterPro.
DR InterPro; IPR015977; Nic_PRibTrfase-like.
DR InterPro; IPR007229; Nic_PRibTrfase-rel.
DR InterPro; IPR006405; Nic_PRibTrfase_put.
DR InterPro; IPR002638; Quinolinate_PRibosylTrfase_C.
DR PANTHER; PTHR11098:SF1; PTHR11098:SF1; 1.
DR Pfam; PF04095; NAPRTase; 1.
DR PIRSF; PIRSF000484; NAPRT; 1.
DR SUPFAM; SSF51690; Q_phspho_trans; 1.
DR TIGRFAMs; TIGR01513; NAPRTase_put; 1.
PE 3: Inferred from homology;
KW Complete proteome; Glycosyltransferase;
KW Pyridine nucleotide biosynthesis; Transferase.
SQ SEQUENCE 461 AA; 50994 MW; EA40B11912AA96F5 CRC64;
MIVEQQDNIP QQSALFTDLY QLRMMQSYYA EEMNAIAVFE LFFRTLPSNR NFVMAAGLDN
ILSYLEQLHV TDGERDWLKE AGGFSPRFCQ QLGDFHFTGD VFAVPEGTVV FENEPVVQVI
APLPEAQLVE TYLLNQIHLQ SVLATKAARV VSAARGHKVV DFGSRRAHGT DAALKIARTS
YLAGVNATSN VFAGRAYGIP VVGTMAHSFI QAHPSEYAAL RAFIQEFPDT TLLVDTYDTL
AGVRKVIALA EALGQDFKVK AIRLDSGDLG KLAKESRRLL DEGGLSQVRI VASSGLDEYK
IQALLAEQTP IDGFGVGTQL AVSGDAPEID FSYKLVEYAG KPRMKLSSSK ELLPGRKQVF
RFFEADRMKR DVIARFEENL AGKPLLEQVM SQGKRLGRGR TSLADAREHA RQQMAALPLE
LHALQRVKFG YPVTVSDSLR QANEQLQREL AVELDPHFGA S
//
