ID   D8NJP0_RALSL            Unreviewed;       529 AA.
AC   D8NJP0;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   03-APR-2013, entry version 18.
DE   RecName: Full=Malate synthase;
DE            EC=2.3.3.9;
GN   Name=aceB; ORFNames=RCFBP_20067;
OS   Ralstonia solanacearum CFBP2957.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ralstonia.
OX   NCBI_TaxID=859656;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CFBP2957;
RA   Remenant B., Coupat-Goutaland B., Guidot A., Cellier G., Wicker E.,
RA   Allen C., Fegan M., Pruvost O., Elbaz M., Calteau A., Salvignol G.,
RA   Mornico D., Mangenot S., Barbe V., Medigue C., Prior P.;
RT   "Genomes of three tomato pathogens within the Ralstonia solanacearum
RT   species complex reveal significant evolutionary divergence.";
RL   BMC Genomics 11:379-379(2010).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CFBP2957;
RA   Genoscope - CEA;
RL   Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: Acetyl-CoA + H(2)O + glyoxylate = (S)-malate +
CC       CoA.
CC   -!- PATHWAY: Carbohydrate metabolism; glyoxylate cycle; (S)-malate
CC       from isocitrate: step 2/2.
CC   -!- SIMILARITY: Belongs to the malate synthase family.
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DR   EMBL; FP885897; CBJ43262.1; -; Genomic_DNA.
DR   RefSeq; YP_003745872.1; NC_014307.1.
DR   EnsemblBacteria; CBJ43262; CBJ43262; RCFBP_20067.
DR   GeneID; 9415649; -.
DR   KEGG; rsc:RCFBP_20067; -.
DR   PATRIC; 42546740; VBIRalSol166517_1891.
DR   HOGENOM; HOG000238464; -.
DR   KO; K01638; -.
DR   UniPathway; UPA00703; UER00720.
DR   GO; GO:0004474; F:malate synthase activity; IEA:EC.
DR   GO; GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
DR   InterPro; IPR011076; Malate_synth-like.
DR   InterPro; IPR006252; Malate_synthA.
DR   InterPro; IPR001465; Malate_synthase.
DR   InterPro; IPR019830; Malate_synthase_CS.
DR   PANTHER; PTHR21631:SF1; PTHR21631:SF1; 1.
DR   Pfam; PF01274; Malate_synthase; 1.
DR   PIRSF; PIRSF001363; Malate_synth; 1.
DR   SUPFAM; SSF51645; Malat_synth_like; 1.
DR   TIGRFAMs; TIGR01344; malate_syn_A; 1.
DR   PROSITE; PS00510; MALATE_SYNTHASE; 1.
PE   3: Inferred from homology;
KW   Acyltransferase; Glyoxylate bypass; Transferase;
KW   Tricarboxylic acid cycle.
FT   ACT_SITE    166    166       Proton acceptor (By similarity).
FT   ACT_SITE    448    448       Proton donor (By similarity).
SQ   SEQUENCE   529 AA;  58868 MW;  5578FEDE6568BBE4 CRC64;
     MATMELTLPQ GMEIKAEILP AYEDILTPDA LALVARLHRA FEPRRRQLLA ARAERAKRLD
     AGERPDFLPE TRHIREGDWT IAKIPPALEC RRVEITGPVD AKMVINAFNS GADSYMTDFE
     DSNAPSWHNQ IQGQVNLKAA IRRTLTLESG GKSYKLNDKI ATLQVRPRGW HLDEKHVTVD
     GQRVSGGIFD FALFFFHNAK EQLARGAGPF FYLPKMESHL EARLWNDVFI AAQQALSLPQ
     GTIKATVLIE TILAAFEMDE ILYELREHSA GLNAGRWDYI FSCIKKFKMD KNFCLADRAK
     VTMTSPFMRA YALLLLKTCH KRGAPAMGGM SALIPIKNDP EKNAIAMQGI ISDKKRDATD
     GYDGGWVAHP GLVEAAMKEF VDVLGEAPNQ IGKQRPDVSV AAADLLNFQP EQPITEAGLR
     MNINVGIHYL GAWLAGNGCV PIHNLMEDAA TAEISRSQVW QWIRSPKGTL DDGTKVTAEL
     VRKLIPEELA KVKADGAVGH FDRAAQIFEQ MSTSESFSEF LTLPLYEEI
//