GenomeNet

Database: UniProt/TrEMBL
Entry: D8Q0I4_SCHCM
LinkDB: D8Q0I4_SCHCM
Original site: D8Q0I4_SCHCM 
ID   D8Q0I4_SCHCM            Unreviewed;      1065 AA.
AC   D8Q0I4;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   20-DEC-2017, entry version 38.
DE   RecName: Full=DNA ligase {ECO:0000256|RuleBase:RU000617};
DE            EC=6.5.1.1 {ECO:0000256|RuleBase:RU000617};
GN   ORFNames=SCHCODRAFT_53697 {ECO:0000313|EMBL:EFI97745.1};
OS   Schizophyllum commune (strain H4-8 / FGSC 9210) (Split gill fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina;
OC   Agaricomycetes; Agaricomycetidae; Agaricales; Schizophyllaceae;
OC   Schizophyllum.
OX   NCBI_TaxID=578458 {ECO:0000313|Proteomes:UP000007431};
RN   [1] {ECO:0000313|EMBL:EFI97745.1, ECO:0000313|Proteomes:UP000007431}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H4-8 / FGSC 9210 {ECO:0000313|Proteomes:UP000007431};
RX   PubMed=20622885; DOI=10.1038/nbt.1643;
RA   Ohm R.A., de Jong J.F., Lugones L.G., Aerts A., Kothe E.,
RA   Stajich J.E., de Vries R.P., Record E., Levasseur A., Baker S.E.,
RA   Bartholomew K.A., Coutinho P.M., Erdmann S., Fowler T.J.,
RA   Gathman A.C., Lombard V., Henrissat B., Knabe N., Kuees U.,
RA   Lilly W.W., Lindquist E., Lucas S., Magnuson J.K., Piumi F.,
RA   Raudaskoski M., Salamov A., Schmutz J., Schwarze F.W.M.R.,
RA   vanKuyk P.A., Horton J.S., Grigoriev I.V., Woesten H.A.B.;
RT   "Genome sequence of the model mushroom Schizophyllum commune.";
RL   Nat. Biotechnol. 28:957-963(2010).
CC   -!- CATALYTIC ACTIVITY: ATP + (deoxyribonucleotide)(n)-3'-hydroxyl +
CC       5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) +
CC       AMP + diphosphate. {ECO:0000256|RuleBase:RU000617}.
CC   -!- SIMILARITY: Belongs to the ATP-dependent DNA ligase family.
CC       {ECO:0000256|RuleBase:RU004196}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; GL377305; EFI97745.1; -; Genomic_DNA.
DR   RefSeq; XP_003032648.1; XM_003032602.1.
DR   STRING; 578458.XP_003032648.1; -.
DR   EnsemblFungi; EFI97745; EFI97745; SCHCODRAFT_53697.
DR   GeneID; 9590663; -.
DR   KEGG; scm:SCHCODRAFT_53697; -.
DR   eggNOG; KOG0966; Eukaryota.
DR   eggNOG; COG1793; LUCA.
DR   InParanoid; D8Q0I4; -.
DR   KO; K10777; -.
DR   OrthoDB; EOG092C18KW; -.
DR   Proteomes; UP000007431; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0071897; P:DNA biosynthetic process; IEA:InterPro.
DR   GO; GO:0051103; P:DNA ligation involved in DNA repair; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   CDD; cd00027; BRCT; 1.
DR   Gene3D; 1.10.3260.10; -; 1.
DR   Gene3D; 3.40.50.10190; -; 2.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR036420; BRCT_dom_sf.
DR   InterPro; IPR000977; DNA_ligase_ATP-dep.
DR   InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR   InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR   InterPro; IPR036599; DNA_ligase_N_sf.
DR   InterPro; IPR029710; LIG4.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   PANTHER; PTHR10459:SF7; PTHR10459:SF7; 1.
DR   Pfam; PF16589; BRCT_2; 2.
DR   Pfam; PF04679; DNA_ligase_A_C; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   Pfam; PF04675; DNA_ligase_A_N; 1.
DR   SMART; SM00292; BRCT; 2.
DR   SUPFAM; SSF117018; SSF117018; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF52113; SSF52113; 2.
DR   TIGRFAMs; TIGR00574; dnl1; 1.
DR   PROSITE; PS50172; BRCT; 2.
DR   PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR   PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000617};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007431};
KW   DNA damage {ECO:0000256|RuleBase:RU000617};
KW   DNA recombination {ECO:0000256|RuleBase:RU000617};
KW   DNA repair {ECO:0000256|RuleBase:RU000617};
KW   DNA replication {ECO:0000256|RuleBase:RU000617};
KW   Ligase {ECO:0000256|RuleBase:RU000617, ECO:0000313|EMBL:EFI97745.1};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000617};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007431}.
FT   DOMAIN      379    513       DNA_LIGASE_A3. {ECO:0000259|PROSITE:
FT                                PS50160}.
FT   DOMAIN      673    768       BRCT. {ECO:0000259|PROSITE:PS50172}.
FT   DOMAIN      952   1063       BRCT. {ECO:0000259|PROSITE:PS50172}.
FT   COILED      876    896       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1065 AA;  120578 MW;  E93BF5EC34468B3E CRC64;
     MQATPAPTEA PGSPQPSQTT ASQQPFPEQP YNTDTLPFHI LTAFFEKLQG ERKQEKRRKL
     LNHWFNKWRE DNGPDLYPVL RLILPHRDRE RNVYGLKEKA LAKLYIKVIP LNKNDPDAMR
     LLYWKKPTEK HASTCASSAA SGDFPTVLYE VVSKRSSVTQ STLTIDDIND MLDQLADMSN
     KSEKQSKIIQ RLYNEATPEQ QLWFARIILK DMNISVKETT VFAVFHPDAQ ALYNTCSDLK
     KVAWQLADPS IRLHEDEKQV KLGQPFMPML CKRPMKRIED TAQEMDGSEF IIEEKLDGER
     MQLHKMGNQY YYSSRKGKDY TYLYGSHVGA GSLTPYIAHR FHKQADSAIL DGEMLVWDPI
     SGRNLPFGTL KTAALDQSKK QAAPRPCLKV FDLLYLNGKS LIDKSTAFRK KNMRLVIEAL
     PGRIEFVDEF KGRTAQDIRE KMDEVMANRG EGLVIKHPKS QYVLNGRNND WIKVKPEYMD
     NMGETVDVLV VAGNYGSGRR SGGVSTLICA VFDDRNTGSF NENESKYATF VRVGSGLTYA
     DYMWLRAKNW KTWDAKNSPT YLQTAKRSHE DKGDVYLEYE DTFILKVKAA EITPSDQYHV
     RYTMRFPRAL SIREEMAPGD CMTASAVVEQ LKTAKKRKME TNKVSSTKKR KVVKKKVEML
     PRFDGPDMKD VKEESDLFKG MKFVVISDPK ARTGEEDRKK LMKLIRSHGG QCPQFAKDPA
     AIVVYNGTST PYDLQLIIRK DTNDVVRPQW VMDCIAKGEL VPMEKKYFFF ATTARKETAE
     YGEDGGAESS GSVTQESSDD EAAAETSQSS KKRKRAGKSA EPETQDKTAD EEKATPAPSK
     PKVDLDPGLA AWLGYDEDDA AGVEDDAGEK DERGGRDDVE SDNDSDNQDV KDEEEEDDMA
     FWFNEDDGDD SATATLPTQK TTQSTADTQK GDDAPTTQPE VKMGDDNAMH YDEELIFKYL
     CFYLDSPSNA RASGMSVKST AHEDEINESF EELRSKIESN GGRVVDLSEP KLTHVVLDKR
     DLSRRIDLMR RTSKPKRRHL VLTAYIDACL EENTLLDEDG ELGHA
//
DBGET integrated database retrieval system