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Database: UniProt/TrEMBL
Entry: D8QE54_SCHCM
LinkDB: D8QE54_SCHCM
Original site: D8QE54_SCHCM 
ID   D8QE54_SCHCM            Unreviewed;       540 AA.
AC   D8QE54;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   25-OCT-2017, entry version 35.
DE   RecName: Full=Glutamate decarboxylase {ECO:0000256|RuleBase:RU361171};
DE            EC=4.1.1.15 {ECO:0000256|RuleBase:RU361171};
GN   ORFNames=SCHCODRAFT_59494 {ECO:0000313|EMBL:EFI94105.1};
OS   Schizophyllum commune (strain H4-8 / FGSC 9210) (Split gill fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina;
OC   Agaricomycetes; Agaricomycetidae; Agaricales; Schizophyllaceae;
OC   Schizophyllum.
OX   NCBI_TaxID=578458 {ECO:0000313|Proteomes:UP000007431};
RN   [1] {ECO:0000313|EMBL:EFI94105.1, ECO:0000313|Proteomes:UP000007431}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H4-8 / FGSC 9210 {ECO:0000313|Proteomes:UP000007431};
RX   PubMed=20622885; DOI=10.1038/nbt.1643;
RA   Ohm R.A., de Jong J.F., Lugones L.G., Aerts A., Kothe E.,
RA   Stajich J.E., de Vries R.P., Record E., Levasseur A., Baker S.E.,
RA   Bartholomew K.A., Coutinho P.M., Erdmann S., Fowler T.J.,
RA   Gathman A.C., Lombard V., Henrissat B., Knabe N., Kuees U.,
RA   Lilly W.W., Lindquist E., Lucas S., Magnuson J.K., Piumi F.,
RA   Raudaskoski M., Salamov A., Schmutz J., Schwarze F.W.M.R.,
RA   vanKuyk P.A., Horton J.S., Grigoriev I.V., Woesten H.A.B.;
RT   "Genome sequence of the model mushroom Schizophyllum commune.";
RL   Nat. Biotechnol. 28:957-963(2010).
CC   -!- CATALYTIC ACTIVITY: L-glutamate = 4-aminobutanoate + CO(2).
CC       {ECO:0000256|RuleBase:RU361171}.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|PIRSR:PIRSR602129-50,
CC         ECO:0000256|RuleBase:RU361171};
CC   -!- SIMILARITY: Belongs to the group II decarboxylase family.
CC       {ECO:0000256|RuleBase:RU361171}.
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DR   EMBL; GL377310; EFI94105.1; -; Genomic_DNA.
DR   RefSeq; XP_003029008.1; XM_003028962.1.
DR   STRING; 578458.XP_003029008.1; -.
DR   EnsemblFungi; EFI94105; EFI94105; SCHCODRAFT_59494.
DR   GeneID; 9591111; -.
DR   KEGG; scm:SCHCODRAFT_59494; -.
DR   eggNOG; KOG1383; Eukaryota.
DR   eggNOG; COG0076; LUCA.
DR   InParanoid; D8QE54; -.
DR   KO; K01580; -.
DR   OrthoDB; EOG092C1P0W; -.
DR   Proteomes; UP000007431; Unassembled WGS sequence.
DR   GO; GO:0004351; F:glutamate decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0006536; P:glutamate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.640.10; -; 1.
DR   Gene3D; 3.90.1150.10; -; 1.
DR   InterPro; IPR010107; Glutamate_decarboxylase.
DR   InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major_sub1.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_sub2.
DR   PANTHER; PTHR43321; PTHR43321; 1.
DR   Pfam; PF00282; Pyridoxal_deC; 1.
DR   SUPFAM; SSF53383; SSF53383; 1.
DR   TIGRFAMs; TIGR01788; Glu-decarb-GAD; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007431};
KW   Decarboxylase {ECO:0000256|RuleBase:RU361171};
KW   Lyase {ECO:0000256|RuleBase:RU361171};
KW   Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR602129-50,
KW   ECO:0000256|RuleBase:RU361171};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007431}.
FT   MOD_RES     299    299       N6-(pyridoxal phosphate)lysine.
FT                                {ECO:0000256|PIRSR:PIRSR602129-50}.
SQ   SEQUENCE   540 AA;  60555 MW;  39EB24021E3CBBD6 CRC64;
     MSLSRHVDPT AVLAAARDHP HRRHVNRHEK SVLGQSWTRD EDATAAPKYT FPTHGIPSKS
     AYQLIHDEAA LDGNPALNLA SFVHTWMPDD GIRLFQEAAN KNLADQDEYP AAQIIHNRCV
     SMLAHLWKAP TAETSAVGTS TAGSSEAIML GGLALKKRWQ EQRKKAGKDY FHPNIVFGSN
     AQVALEKFAR RVAYWDVEAR LVPVNSSTSY VMKPEDAIQF IDENTIGVMV ILGSTYNGAF
     EDVARMSDLL DDLQERTGLD IPIHVDAASG GFIAPFAYPQ HKWAFDVSRV VSINSSGHKF
     GLVYAGLGWL IFRDESCLHK DLIFELHYLG STEYSYTLNF SKPASPVFAQ MFNFLNLGYN
     GYAKIAYKDL RNARILARAL ENTYFTILSD IHRKAPDAPA DVDEEDPNYY VKGLPVVSFR
     FNDEYRQKYP HVKQAWMQTS LRTKGWIVPN YNAPKGEEKT EMLRVVMRES ITEDLVERLV
     VDILECAEAF MAPEGSDMMI ASAGGTMHQP DIEHSRPQPH NFSTSSDTEG LEQSGYSRQC
//
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