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Database: UniProt/TrEMBL
Entry: D9QEF7_CORP2
LinkDB: D9QEF7_CORP2
Original site: D9QEF7_CORP2 
ID   D9QEF7_CORP2            Unreviewed;       694 AA.
AC   D9QEF7;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   25-OCT-2017, entry version 43.
DE   SubName: Full=Neuraminidase (Sialidase) {ECO:0000313|EMBL:ADL09880.1};
GN   Name=nanH {ECO:0000313|EMBL:ADL09880.1};
GN   OrderedLocusNames=CpC231_0390 {ECO:0000313|EMBL:ADL09880.1};
OS   Corynebacterium pseudotuberculosis (strain C231).
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=681645 {ECO:0000313|EMBL:ADL09880.1, ECO:0000313|Proteomes:UP000000276};
RN   [1] {ECO:0000313|EMBL:ADL09880.1, ECO:0000313|Proteomes:UP000000276}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C231 {ECO:0000313|EMBL:ADL09880.1,
RC   ECO:0000313|Proteomes:UP000000276};
RX   PubMed=21037006; DOI=10.1128/JB.01211-10;
RG   Consortium: Rede Paraense de Genomica e Proteomica (RPGP);
RA   Silva A., Schneider M.P., Cerdeira L., Barbosa M.S., Ramos R.T.,
RA   Carneiro A.R., Santos R., Lima M., D'Afonseca V., Almeida S.S.,
RA   Santos A.R., Soares S.C., Pinto A.C., Ali A., Dorella F.A., Rocha F.,
RA   de Abreu V.A., Trost E., Tauch A., Shpigel N., Miyoshi A., Azevedo V.;
RT   "Complete genome sequence of Corynebacterium pseudotuberculosis I19, a
RT   strain isolated from a cow in Israel with bovine mastitis.";
RL   J. Bacteriol. 193:323-324(2011).
RN   [2] {ECO:0000313|EMBL:ADL09880.1, ECO:0000313|Proteomes:UP000000276}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C231 {ECO:0000313|EMBL:ADL09880.1,
RC   ECO:0000313|Proteomes:UP000000276};
RX   PubMed=21533164; DOI=10.1371/journal.pone.0018551;
RA   Ruiz J.C., D'Afonseca V., Silva A., Ali A., Pinto A.C., Santos A.R.,
RA   Rocha A.A., Lopes D.O., Dorella F.A., Pacheco L.G., Costa M.P.,
RA   Turk M.Z., Seyffert N., Moraes P.M., Soares S.C., Almeida S.S.,
RA   Castro T.L., Abreu V.A., Trost E., Baumbach J., Tauch A.,
RA   Schneider M.P., McCulloch J., Cerdeira L.T., Ramos R.T., Zerlotini A.,
RA   Dominitini A., Resende D.M., Coser E.M., Oliveira L.M., Pedrosa A.L.,
RA   Vieira C.U., Guimaraes C.T., Bartholomeu D.C., Oliveira D.M.,
RA   Santos F.R., Rabelo E.M., Lobo F.P., Franco G.R., Costa A.F.,
RA   Castro I.M., Dias S.R., Ferro J.A., Ortega J.M., Paiva L.V.,
RA   Goulart L.R., Almeida J.F., Ferro M.I., Carneiro N.P., Falcao P.R.,
RA   Grynberg P., Teixeira S.M., Brommonschenkel S., Oliveira S.C.,
RA   Meyer R., Moore R.J., Miyoshi A., Oliveira G.C., Azevedo V.;
RT   "Evidence for reductive genome evolution and lateral acquisition of
RT   virulence functions in two Corynebacterium pseudotuberculosis
RT   strains.";
RL   PLoS ONE 6:E18551-E18551(2011).
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DR   EMBL; CP001829; ADL09880.1; -; Genomic_DNA.
DR   RefSeq; WP_013241243.1; NC_017301.1.
DR   CAZy; GH33; Glycoside Hydrolase Family 33.
DR   EnsemblBacteria; ADL09880; ADL09880; CpC231_0390.
DR   GeneID; 12298128; -.
DR   KEGG; cpq:CpC231_0390; -.
DR   PATRIC; fig|681645.3.peg.407; -.
DR   HOGENOM; HOG000143321; -.
DR   KO; K01186; -.
DR   OMA; GADCLSE; -.
DR   Proteomes; UP000000276; Chromosome.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; PTHR10628; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; SSF50939; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000276};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000276};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     31       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        32    694       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003126516.
FT   DOMAIN      136    472       Sialidase. {ECO:0000259|Pfam:PF13088}.
FT   COILED      516    648       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   694 AA;  74683 MW;  1A2153BDD42088AE CRC64;
     MTDSHRRGTR KALVTLTAAL ALTTQGLTAP ATLAEEGSTI VPAPIDNNGL FDAAPPAPVA
     RGAVGEGKLP DPVTSEFFDS KVIRDVDPAG QRCFRIPAIA TAVDGTLLVA FDNRYGPDAQ
     SRTWCRDAPY ENTKRNSREK QTDIEIYRSH DSGKSFEEGD FIAKGTEDPR DLSYTDPSIV
     VDHETGKIFA VFVRGYDYRF FDATAGVNRG SVEDPIQKRS VQDTVIIESN DNGQTWGNMK
     LLSELTEKIK VRHKPGQELA GRGRFATSGN GIQLKYGENA GRLLFPMSVH YSPNGAGAVA
     NVALYSDDHG ATWNVGQGVG GEGETNGDEN KLVELSDGRI MMNSKSTGSN PSNPRGAERW
     RSYSEDQGET WSKPEPVIVA PPQHPLQRNT GINVSLIKAY PSAPEGSAAA RVLLYSAPID
     TRIKGEYGQD GRSNGWVMAS CDDGRSWTHG RQIEAGRFQY SVMTPMADGN IGMVYESGDK
     ERGMTLKFAK FNMAWLGADC LSNKALGITD LPDPALAKAI EDAKAATAKA EEATANVLKL
     TKELEEAELE NEELAQALAE AKSAAQDAIA AAEEANARVK AAEGATIEAE EAAMKAENEA
     KALAEQLAKV EAELANSQDQ AKALAEAKEA AEIARKAAEE ALKLEKEKSG KAGGTDNTEN
     KGFWQELLRI FPGFAPIFSF LASIWGGMQK LLAF
//
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