ID   D9QQE0_ACEAZ            Unreviewed;       541 AA.
AC   D9QQE0;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   01-MAY-2013, entry version 17.
DE   SubName: Full=Thiamine pyrophosphate protein TPP binding domain protein;
GN   OrderedLocusNames=Acear_1212;
OS   Acetohalobium arabaticum (strain ATCC 49924 / DSM 5501 / Z-7288).
OC   Bacteria; Firmicutes; Clostridia; Halanaerobiales; Halobacteroidaceae;
OC   Acetohalobium.
OX   NCBI_TaxID=574087;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49924 / DSM 5501 / Z-7288;
RX   DOI=10.4056/sigs.1062906;
RA   Sikorski J., Lapidus A., Chertkov O., Lucas S., Copeland A.,
RA   Glavina Del Rio T., Nolan M., Tice H., Cheng J., Han C., Brambilla E.,
RA   Pitluck S., Liolios K., Ivanova N., Mavromatis K., Mikhailova N.,
RA   Pati A., Bruce D., Detter C., Tapia R., Goodwin L., Chen A.,
RA   Palaniappan K., Land M., Hauser L., Chang Y., Jeffries C., Rohde M.,
RA   Goker M., Spring S., Woyke T., Bristow J., Eisen J., Markowitz V.,
RA   Hugenholtz P., Kyrpides N., Klenk H.;
RT   "Complete genome sequence of Acetohalobium arabaticum type strain (Z-
RT   7288).";
RL   Stand. Genomic Sci. 3:57-65(2010).
CC   -!- SIMILARITY: Belongs to the TPP enzyme family.
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DR   EMBL; CP002105; ADL12731.1; -; Genomic_DNA.
DR   RefSeq; YP_003827796.1; NC_014378.1.
DR   EnsemblBacteria; ADL12731; ADL12731; Acear_1212.
DR   GeneID; 9513254; -.
DR   KEGG; aar:Acear_1212; -.
DR   PATRIC; 42136639; VBIAceAra30843_1244.
DR   HOGENOM; HOG000258446; -.
DR   KO; K01652; -.
DR   BioCyc; AARA574087:GHPK-1278-MONOMER; -.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   GO; GO:0008152; P:metabolic process; IEA:GOC.
DR   InterPro; IPR012000; Thiamin_PyroP_enz_cen_dom.
DR   InterPro; IPR012001; Thiamin_PyroP_enz_TPP-bd_dom.
DR   InterPro; IPR011766; TPP_enzyme-bd_C.
DR   Pfam; PF02775; TPP_enzyme_C; 1.
DR   Pfam; PF00205; TPP_enzyme_M; 1.
DR   Pfam; PF02776; TPP_enzyme_N; 1.
PE   3: Inferred from homology;
KW   Complete proteome.
SQ   SEQUENCE   541 AA;  59414 MW;  4E44CED8CF533EC3 CRC64;
     MEKEINQIGA DLVVKALEKL QVETIFGIPG IHNLDVYDSL LSSDLEHVTA RHEQGAGFMA
     DGYARTNEKP GVCLVISGPG ITNIITPMGQ AMADSVPMVV ISSQLPTSVL DQGTGSLHEL
     KNSTYLTKSV AKESKRVMHK DKIRSSIEEA YHLAMTGRPG PVHVEIPLDI LQAPISKVES
     SIMNNYISYD PWEDLNQDNK IESAANLLQE ADRPMIIAGG GSSQSTEELR KLVEELEIPL
     VQTIAGKGVI SEEHLLCLGA SIKFDSIQKR IKNADCVLAV GTELAPTDLE GTELKIEGIL
     IQIDMDPGNF QRNFAADISL RGDAQRILSE VIDRLDFKEN SNNQLKLEEL GHSKEELVEH
     RGIDEKELDF TLDMLNVIRE AVPEGGVLVT DMTSPAYVAR SEYPAYSPRT FLHPVGYGTL
     GYALPAAAGA KFANPNKDVV ALTGDGGFQF TMQELGVLLE HQFSLPIIIW NNDGFGEIRR
     NEELRHPNET IAVNHKNPNL EDLARSYEFS FSSVTNSSEL KTVLEDALAK PKPEIIEIKA
     K
//