ID D9SST4_CLOC7 Unreviewed; 366 AA.
AC D9SST4;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 01-MAY-2013, entry version 15.
DE RecName: Full=6-phosphofructokinase;
DE Short=Phosphofructokinase;
DE EC=2.7.1.11;
DE AltName: Full=Phosphohexokinase;
GN Name=pfkA; OrderedLocusNames=Clocel_2901;
OS Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 /
OS 743B).
OC Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=573061;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35296 / DSM 3052 / OCM 3 / 743B;
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N.,
RA Mikhailova N., Hemme C.L., Woyke T.;
RT "Complete sequence of Clostridium cellulovorans 743B.";
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY: ATP + D-fructose 6-phosphate = ADP + D-
CC fructose 1,6-bisphosphate.
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC phosphate and glycerone phosphate from D-glucose: step 3/4.
CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC -!- SIMILARITY: Belongs to the phosphofructokinase family.
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DR EMBL; CP002160; ADL52596.1; -; Genomic_DNA.
DR RefSeq; YP_003844360.1; NC_014393.1.
DR ProteinModelPortal; D9SST4; -.
DR EnsemblBacteria; ADL52596; ADL52596; Clocel_2901.
DR GeneID; 9609791; -.
DR KEGG; ccb:Clocel_2901; -.
DR PATRIC; 41737482; VBICloCel81632203721_2512.
DR HOGENOM; HOG000248869; -.
DR KO; K00850; -.
DR BioCyc; CCEL573061:GIXD-2983-MONOMER; -.
DR UniPathway; UPA00109; UER00182.
DR GO; GO:0005945; C:6-phosphofructokinase complex; IEA:InterPro.
DR GO; GO:0003872; F:6-phosphofructokinase activity; IEA:HAMAP.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006002; P:fructose 6-phosphate metabolic process; IEA:InterPro.
DR GO; GO:0006096; P:glycolysis; IEA:HAMAP.
DR HAMAP; MF_00339; Phosphofructokinase; 1; -.
DR InterPro; IPR012003; ATP_PFK_prok.
DR InterPro; IPR012829; PFK.
DR InterPro; IPR022953; Phosphofructokinase.
DR InterPro; IPR015912; Phosphofructokinase_CS.
DR InterPro; IPR000023; Phosphofructokinase_dom.
DR Pfam; PF00365; PFK; 1.
DR PIRSF; PIRSF000532; ATP_PFK_prok; 1.
DR PRINTS; PR00476; PHFRCTKINASE.
DR SUPFAM; SSF53784; Ppfruckinase; 1.
DR TIGRFAMs; TIGR02483; PFK_mixed; 1.
DR PROSITE; PS00433; PHOSPHOFRUCTOKINASE; 1.
PE 3: Inferred from homology;
KW ATP-binding; Complete proteome; Cytoplasm; Glycolysis; Kinase;
KW Nucleotide-binding; Transferase.
FT NP_BIND 26 30 ATP (By similarity).
FT NP_BIND 171 175 ATP (By similarity).
FT NP_BIND 188 204 ATP (By similarity).
FT ACT_SITE 144 144 Proton acceptor (By similarity).
FT BINDING 179 179 Substrate (By similarity).
FT BINDING 284 284 Substrate (By similarity).
FT BINDING 290 290 Substrate (By similarity).
FT BINDING 293 293 Substrate (By similarity).
SQ SEQUENCE 366 AA; 39689 MW; 8637CA4940435B7C CRC64;
MQEQKIKKIA LLTGGGDCPG LNAVIRAVTR TAILKYGYEV IGYIFGYRGL YNNDFIPLTL
DKVSGIGHKG GTILYSSNKD NLFDYQVEEN GEIVKKDVSD VAIENLKKEG VDAIVVIGGD
GTLTSARDFS RKGINVIGVP KTIDNDLPAT EVTFGFNTAV EVATEALDRL HTTAESHHRV
MLLEVMGRNA GWIALHSGLA GSADVILIPE IPYDLHKVAE KIEMRQREGK KFTIIVVAEG
AKPKDGDVVV AKVVDDSPDP IRLGGIANKL AADLEKIIKN QEIRATILGH IQRGGITSAY
DRILSTRYGV AATELIHEGK FGNMVTLKED KISYEALEKV IGHTRVVEPD GELIQTARSI
GVSFGD
//
