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Database: UniProt/TrEMBL
Entry: D9TCU1_MICAI
LinkDB: D9TCU1_MICAI
Original site: D9TCU1_MICAI 
ID   D9TCU1_MICAI            Unreviewed;      1247 AA.
AC   D9TCU1;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   05-JUL-2017, entry version 42.
DE   SubName: Full=2-oxoglutarate dehydrogenase, E1 subunit {ECO:0000313|EMBL:ADL48728.1};
GN   OrderedLocusNames=Micau_5222 {ECO:0000313|EMBL:ADL48728.1};
OS   Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / BCRC 12538
OS   / CBS 129.76 / JCM 10878 / NBRC 16125 / NRRL B-16091 / INA 9442).
OC   Bacteria; Actinobacteria; Micromonosporales; Micromonosporaceae;
OC   Micromonospora.
OX   NCBI_TaxID=644283 {ECO:0000313|EMBL:ADL48728.1, ECO:0000313|Proteomes:UP000001908};
RN   [1] {ECO:0000313|EMBL:ADL48728.1, ECO:0000313|Proteomes:UP000001908}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442
RC   {ECO:0000313|Proteomes:UP000001908};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M.,
RA   Hauser L., Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N.,
RA   Ovchinnikova G., Hirsch A.M., Woyke T.;
RT   "Complete sequence of Micromonospora aurantiaca ATCC 27029.";
RL   Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP002162; ADL48728.1; -; Genomic_DNA.
DR   RefSeq; WP_013288340.1; NC_014391.1.
DR   ProteinModelPortal; D9TCU1; -.
DR   STRING; 644283.Micau_5222; -.
DR   EnsemblBacteria; ADL48728; ADL48728; Micau_5222.
DR   GeneID; 32165771; -.
DR   KEGG; mau:Micau_5222; -.
DR   eggNOG; ENOG4105C7P; Bacteria.
DR   eggNOG; COG0508; LUCA.
DR   eggNOG; COG0567; LUCA.
DR   HOGENOM; HOG000259587; -.
DR   KO; K00164; -.
DR   OMA; IDMVCYR; -.
DR   OrthoDB; POG091H03SK; -.
DR   Proteomes; UP000001908; Chromosome.
DR   GO; GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:InterPro.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:InterPro.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR   InterPro; IPR032106; 2-oxogl_dehyd_N.
DR   InterPro; IPR011603; 2oxoglutarate_DH_E1.
DR   InterPro; IPR001017; DH_E1.
DR   InterPro; IPR031717; KGD_C.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   PANTHER; PTHR23152; PTHR23152; 1.
DR   Pfam; PF00198; 2-oxoacid_dh; 1.
DR   Pfam; PF16078; 2-oxogl_dehyd_N; 1.
DR   Pfam; PF00676; E1_dh; 1.
DR   Pfam; PF16870; OxoGdeHyase_C; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   PIRSF; PIRSF000157; Oxoglu_dh_E1; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; SSF52518; 2.
DR   TIGRFAMs; TIGR00239; 2oxo_dh_E1; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001908};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001908}.
FT   DOMAIN      904   1099       Transket_pyr. {ECO:0000259|SMART:
FT                                SM00861}.
SQ   SEQUENCE   1247 AA;  137849 MW;  66EFC4DA35291137 CRC64;
     MSTQQTSQEN PLAGFGPNEW IVEEMYQRYL ADPSSVDSAW HDFFADYRPA PGAATPRPDG
     QAKPAAKPEP AEQQEAVATV TAQPAKTEPK AAPKATPAPA KPAAKPAAKA PEPAKKSAPA
     KPAAKAPTAS AAGTTPLRGV AAKIVQNMDA SLAVPTATSV RAVPAKLLVD NRIVINNHLT
     RGRGGKVSFT HLIGYALVRA VVEHPEMNNS FAEVDGKPAM VRPEHVNLGI AIDLVKPDGS
     RNLVVPSIKG CEQMDFRQFW QAYEDVVRRA RRNELTMEDY SGTTISLTNP GGIGTVHSIP
     RLMQGQSAII GVGAMEYPAP YQGMSEATLA ENAVSKVITL TSTYDHRIIQ GAQSGEFLKV
     MHELLLGERG FYDDIFTSLR IPYEPVRWMR DVAVDSEGQI NKTARVHELI HAYRVRGHLM
     ADTDPLEFKI RKHPDLDVLQ HGLTLWDLDR VFPVNGFAGQ QRMKLRSILG VLRDSYCRRV
     GIEYMHIQDP EERRWIQERV ERKYEKPSSD EQKHVLNRLN AAEAFETFLQ TKYVGQKRFS
     LEGGESLIPL LGEVLECSAE AGLDEVVIGM AHRGRLNVLA NIVGKPYEKI FSEFEGHLDP
     RSTQGSGDVK YHLGQNGKFT TPDGEHAVKV SVVANPSHLE AVDPVLEGIV RAKQDRIDLK
     LEGYTVLPLA VHGDAAFAGQ GVVAETLNLS QLRGYRTGGT VHVVVNNQVG FTTAPEYSRS
     SLYSTDVARM IQAPIFHVNG DDPEAVVRVA RLAFEYRQAF NKDVVIDMVC YRRRGHNEGD
     DPSMSNPEMY KIIDSKRSVR KLYTEELIGR GDITVEDAEE LLRDYQGQLE RVFKATRDAA
     TTPRQLSRPA REEEPEPQVD TATDAAVVKA IGEAHVNLPE GFTPHKRIQQ LLERRRKMSV
     EGGIDWGFAE IIAFGTLLHD GVTVRLAGQD SRRGTFVQRH ASVVDAKTGE DYLPLKSLTA
     DGERSRFFVH DSLLSEYAAM GFEYGYSVEN INALVAWEAQ FGDFVNGAQS VIDEFISSGE
     VKWGQRSAVT LLLPHGHEGQ GPDHTSGRPE RFLQLCAEDN MRVAIPTTPA NYFHLLRRQA
     LSPKRKPLVV FTPKSLLRHK LCVSPVEDFT TGTFQPVLAD TAAPAPEQVK RVLLCSGKVY
     YDLFQARQER GVTDTAILRM EQLYPLPVEE VRAALAQYPN AEDFAWVQEE PANQGAWSFV
     ALNLLEHLPE VRLRRISRPA AAAPAVGSAK MHEVEQNALI EAALPRP
//
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