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Database: UniProt/TrEMBL
Entry: E0V954_PEDHC
LinkDB: E0V954_PEDHC
Original site: E0V954_PEDHC 
ID   E0V954_PEDHC            Unreviewed;      1219 AA.
AC   E0V954;
DT   02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2010, sequence version 1.
DT   29-OCT-2014, entry version 15.
DE   RecName: Full=Piwi-like protein {ECO:0000256|RuleBase:RU361178};
GN   ORFNames=Phum_PHUM004130 {ECO:0000313|EMBL:EEB09910.1};
OS   Pediculus humanus subsp. corporis (Body louse).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Paraneoptera; Phthiraptera; Anoplura;
OC   Pediculidae; Pediculus.
OX   NCBI_TaxID=121224 {ECO:0000313|Proteomes:UP000009046};
RN   [1] {ECO:0000313|Proteomes:UP000009046}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USDA {ECO:0000313|Proteomes:UP000009046};
RX   PubMed=20566863; DOI=10.1073/pnas.1003379107;
RA   Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A.,
RA   Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E.,
RA   Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A.,
RA   Veenstra J.A., Walenz B., Tubio J.M., Ribeiro J.M., Rozas J.,
RA   Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L.,
RA   Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M.,
RA   Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P.,
RA   Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M.,
RA   Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F.,
RA   Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G.,
RA   Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C.,
RA   Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L.,
RA   Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C.,
RA   Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M.,
RA   Pittendrigh B.R.;
RT   "Genome sequences of the human body louse and its primary endosymbiont
RT   provide insights into the permanent parasitic lifestyle.";
RL   Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010).
CC   -!- SIMILARITY: Belongs to the argonaute family. Piwi subfamily.
CC       {ECO:0000256|RuleBase:RU361178}.
CC   -!- SIMILARITY: Contains 1 PAZ domain.
CC       {ECO:0000256|RuleBase:RU361178}.
CC   -!- SIMILARITY: Contains 1 PIWI domain.
CC       {ECO:0000256|RuleBase:RU361178}.
CC   -!- SIMILARITY: Contains Piwi domain. {ECO:0000256|SAAS:SAAS00097270}.
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DR   EMBL; DS234988; EEB09910.1; -; Genomic_DNA.
DR   RefSeq; XP_002422648.1; XM_002422603.1.
DR   EnsemblMetazoa; PHUM004130-RA; PHUM004130-PA; PHUM004130.
DR   GeneID; 8233388; -.
DR   KEGG; phu:Phum_PHUM004130; -.
DR   VectorBase; PHUM004130; Pediculus humanus.
DR   CTD; 8233388; -.
DR   InParanoid; E0V954; -.
DR   KO; K11593; -.
DR   OMA; QGQEGGY; -.
DR   OrthoDB; EOG7NPFSH; -.
DR   PhylomeDB; E0V954; -.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 3.30.420.10; -; 1.
DR   InterPro; IPR003100; PAZ_dom.
DR   InterPro; IPR003165; Piwi.
DR   InterPro; IPR012337; RNaseH-like_dom.
DR   Pfam; PF02170; PAZ; 1.
DR   Pfam; PF02171; Piwi; 1.
DR   SMART; SM00949; PAZ; 1.
DR   SMART; SM00950; Piwi; 1.
DR   SUPFAM; SSF101690; SSF101690; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   PROSITE; PS50821; PAZ; 1.
DR   PROSITE; PS50822; PIWI; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000009046};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009046}.
SQ   SEQUENCE   1219 AA;  139392 MW;  2D370587E84C026B CRC64;
     MTEKKWYHKK NKKDKTEHHA DKHKPGFSGD SQPVAGETSS FEKVSSEKMP KSRSEIDFDK
     TKQEMPQSFK HQKQQLSSTE KEGVESHQKQ QPSDYSKSET QIQQKHKNPK QKMKVQRQPD
     LPISEKQPPS AQGAKQQPQQ QQQQSQSSMQ PPSAWGVKQQ PQQQQQQQPQ SSMQPPSAWG
     VKQQPQQQQQ QQQQSSVQSP SAWGVKEQPK YKNSKGSERF FEDSKYKKGW DKKNTAKQQL
     SSAEEGGDEP HQKQQPSDSS KSETQFQQKQ KNPKQKMKVQ RQPDLPISEK QPPSAQDAKQ
     QPQQQQQQQP QSSMQPPSAW GVKQQPQQQQ QQQPQSSVQP PSAWGVKEQP EHKNSKKSEK
     FFKDSKNKKV GDTKNIPKEG KGDSRDPSAK STELITQKLD KMNLEKGQEG RRSPNSPDKQ
     LIPFAQKIVD PRKDGRRILV DTNYFPLRIS NPNVIVYHYD VVFNPDTPKF MLRLAWNKYA
     SDNFKNRITV FDGKKNAYSK GPLISNGNCH SAGVSIVNPN SGKIREFSVS IQEVRQDYKQ
     SLEHNVKLPE AEISVLEIIL KNGPSNTLVP CGRSFFPKSQ MGIRARSISS CLDYRAGHYQ
     AATLGDRIYL NFDLAQKAFY KSLPVIDVAY SFTSSYNNRI NLDSLNYFLK GAKVEYKLPN
     SSDPGKIYKV NGLVGNAEEE TFEKDTITMT VATYFAKDKK YPLKHSHLPL LWVGSTQRKI
     YLPMEFCRIV EDQVFMGEMS PDETREMVKL ATSDAKTRKK DILYVFNKAN FSNNIYMKEF
     GLSVDKDMER IQARILEPPS LRTKGSVFVK DGQWKIRDFF TPTVLDNWCI LYFDNCVRKE
     NLNDFQNLIK RKGTEFNMQV KDAIRNPVGG NSHPRELART LQELKQMKLV FVIIPETKGL
     YSKIKNICET QEGILTQCVR ARTLCQDFRK FSTTVENILL KVNAKLGGRN VSLDKNSFPT
     CLEGLVMVIG ADVTHSGPGS RIPSVAAVAV SCDPQAFQYG ISTRVQIGEI IQDMENIIGE
     HLRKFYQIRQ NYPEKIIFFR DGVSEGELPI MMKTELEAIK RACSRVPSCR PKITMIVVQK
     RHHTRFYPVN DADAIGRNFN VPVGTCVDTD IVHPRDLDFY LVSHASILGT ARPTRYRLLY
     DDNRLTDDEI EKMSFYLCHM FSRCNRSVSY PSPTYNAHLA AFRVRAYLEA RNLSKNDDLK
     SIQAKLKDVI SQKNPMFFV
//
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