GenomeNet

Database: UniProt/TrEMBL
Entry: E0VG95_PEDHC
LinkDB: E0VG95_PEDHC
Original site: E0VG95_PEDHC 
ID   E0VG95_PEDHC            Unreviewed;       451 AA.
AC   E0VG95;
DT   02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2010, sequence version 1.
DT   11-JUN-2014, entry version 17.
DE   RecName: Full=Ribosomal protein S6 kinase;
DE            EC=2.7.11.1;
GN   ORFNames=Phum_PHUM176660;
OS   Pediculus humanus subsp. corporis (Body louse).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Paraneoptera; Phthiraptera; Anoplura;
OC   Pediculidae; Pediculus.
OX   NCBI_TaxID=121224;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USDA;
RX   PubMed=20566863; DOI=10.1073/pnas.1003379107;
RA   Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A.,
RA   Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E.,
RA   Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A.,
RA   Veenstra J.A., Walenz B., Tubio J.M., Ribeiro J.M., Rozas J.,
RA   Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L.,
RA   Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M.,
RA   Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P.,
RA   Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M.,
RA   Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F.,
RA   Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G.,
RA   Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C.,
RA   Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L.,
RA   Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C.,
RA   Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M.,
RA   Pittendrigh B.R.;
RT   "Genome sequences of the human body louse and its primary endosymbiont
RT   provide insights into the permanent parasitic lifestyle.";
RL   Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010).
CC   -!- CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.
CC   -!- SIMILARITY: Belongs to the protein kinase superfamily. AGC Ser/Thr
CC       protein kinase family. S6 kinase subfamily.
CC   -!- SIMILARITY: Contains AGC-kinase C-terminal domain.
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DR   EMBL; DS235133; EEB12401.1; -; Genomic_DNA.
DR   RefSeq; XP_002425139.1; XM_002425094.1.
DR   ProteinModelPortal; E0VG95; -.
DR   GeneID; 8236794; -.
DR   KEGG; phu:Phum_PHUM176660; -.
DR   VectorBase; PHUM176660; Pediculus humanus.
DR   CTD; 8236794; -.
DR   KO; K04688; -.
DR   OMA; ANRMPAR; -.
DR   OrthoDB; EOG7B8S38; -.
DR   PhylomeDB; E0VG95; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   InterPro; IPR000961; AGC-kinase_C.
DR   InterPro; IPR011009; Kinase-like_dom.
DR   InterPro; IPR017892; Pkinase_C.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR016238; Ribosomal_S6_kinase.
DR   InterPro; IPR002290; Ser/Thr_dual-sp_kinase_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   Pfam; PF00069; Pkinase; 1.
DR   Pfam; PF00433; Pkinase_C; 1.
DR   PIRSF; PIRSF000605; Ribsml_S6_kin_1; 1.
DR   SMART; SM00133; S_TK_X; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; SSF56112; 1.
DR   PROSITE; PS51285; AGC_KINASE_CTER; 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Kinase; Nucleotide-binding;
KW   Reference proteome; Serine/threonine-protein kinase; Transferase.
SQ   SEQUENCE   451 AA;  50824 MW;  DA2821970ED732B5 CRC64;
     MAGVFDIELH DENVDKDDSD DDGIDIEEVN NNLMKFQIIF SEDLETVQLS EQTVNLGKEK
     TGPEDFSLLK VLGKGGYGKV FQVKKVTGQD SGTIFAMKVL KKASIVRNQK DTAHTKAERN
     ILEAVKHPFI VDLKYAFQTG GKLYLILEYL SGGELFMHLE REGIFLEESA CFYLSEIILA
     LEHLHNQGII YRDLKPENVL LDAQGHVKLT DFGLCKEHIQ EGIVTHTFCG TIEYMAPEIL
     TRSGHGKAVD WWSLGALLYD MLTGNPPFTA ENRKKTIEII LKGKLNLPPY VTPDARDLIR
     KLLKRQVNQR LGSGAEDGKA IRRHAFFKHI NWSDVISRKL EPPFKPCLTS EDDVSQFDTK
     FTKQTPFDSP DDYTLSESAN RVFQGFTYVA PSVLEEMSRP PHIVKARSPR KGPMSSIRSP
     YNSRFPHSMT GMTSILNTGE ELMEVSGLSH V
//
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