ID E0VG95_PEDHC Unreviewed; 451 AA.
AC E0VG95;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 03-OCT-2012, entry version 13.
DE SubName: Full=RAC protein kinase DRAC-PK85, putative;
DE EC=2.7.11.13;
GN ORFNames=Phum_PHUM176660;
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC Pterygota; Neoptera; Paraneoptera; Phthiraptera; Anoplura;
OC Pediculidae; Pediculus.
OX NCBI_TaxID=121224;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=USDA;
RX PubMed=20566863; DOI=10.1073/pnas.1003379107;
RA Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A.,
RA Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E.,
RA Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A.,
RA Veenstra J.A., Walenz B., Tubio J.M., Ribeiro J.M., Rozas J.,
RA Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L.,
RA Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M.,
RA Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P.,
RA Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M.,
RA Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F.,
RA Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G.,
RA Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C.,
RA Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L.,
RA Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C.,
RA Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M.,
RA Pittendrigh B.R.;
RT "Genome sequences of the human body louse and its primary endosymbiont
RT provide insights into the permanent parasitic lifestyle.";
RL Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010).
CC -!- CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.
CC -!- SIMILARITY: Contains 1 AGC-kinase C-terminal domain.
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DR EMBL; DS235133; EEB12401.1; -; Genomic_DNA.
DR RefSeq; XP_002425139.1; XM_002425094.1.
DR ProteinModelPortal; E0VG95; -.
DR GeneID; 8236794; -.
DR KEGG; phu:Phum_PHUM176660; -.
DR VectorBase; PHUM176660; Pediculus humanus.
DR CTD; 8236794; -.
DR KO; K04688; -.
DR OMA; ANRMPAR; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004697; F:protein kinase C activity; IEA:EC.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR InterPro; IPR000961; AGC-kinase_C.
DR InterPro; IPR011009; Kinase-like_dom.
DR InterPro; IPR017892; Pkinase_C.
DR InterPro; IPR000719; Prot_kinase_cat_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR016238; Ribosomal_S6_kinase.
DR InterPro; IPR002290; Ser/Thr_dual-sp_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF00433; Pkinase_C; 1.
DR PIRSF; PIRSF000605; Ribsml_S6_kin_1; 1.
DR SMART; SM00133; S_TK_X; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Kinase_like; 1.
DR PROSITE; PS51285; AGC_KINASE_CTER; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding; Complete proteome; Kinase; Nucleotide-binding;
KW Reference proteome; Serine/threonine-protein kinase; Transferase.
SQ SEQUENCE 451 AA; 50824 MW; DA2821970ED732B5 CRC64;
MAGVFDIELH DENVDKDDSD DDGIDIEEVN NNLMKFQIIF SEDLETVQLS EQTVNLGKEK
TGPEDFSLLK VLGKGGYGKV FQVKKVTGQD SGTIFAMKVL KKASIVRNQK DTAHTKAERN
ILEAVKHPFI VDLKYAFQTG GKLYLILEYL SGGELFMHLE REGIFLEESA CFYLSEIILA
LEHLHNQGII YRDLKPENVL LDAQGHVKLT DFGLCKEHIQ EGIVTHTFCG TIEYMAPEIL
TRSGHGKAVD WWSLGALLYD MLTGNPPFTA ENRKKTIEII LKGKLNLPPY VTPDARDLIR
KLLKRQVNQR LGSGAEDGKA IRRHAFFKHI NWSDVISRKL EPPFKPCLTS EDDVSQFDTK
FTKQTPFDSP DDYTLSESAN RVFQGFTYVA PSVLEEMSRP PHIVKARSPR KGPMSSIRSP
YNSRFPHSMT GMTSILNTGE ELMEVSGLSH V
//
