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Database: UniProt/TrEMBL
Entry: E0VLU5_PEDHC
LinkDB: E0VLU5_PEDHC
Original site: E0VLU5_PEDHC 
ID   E0VLU5_PEDHC            Unreviewed;       729 AA.
AC   E0VLU5;
DT   02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2010, sequence version 1.
DT   25-OCT-2017, entry version 45.
DE   SubName: Full=Enhancer of zeste, ezh, putative {ECO:0000313|EMBL:EEB14351.1, ECO:0000313|VectorBase:PHUM294210-PA};
DE            EC=2.1.1.43 {ECO:0000313|EMBL:EEB14351.1};
GN   Name=8229722 {ECO:0000313|VectorBase:PHUM294210-PA};
GN   ORFNames=Phum_PHUM294210 {ECO:0000313|EMBL:EEB14351.1};
OS   Pediculus humanus subsp. corporis (Body louse).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura;
OC   Pediculidae; Pediculus.
OX   NCBI_TaxID=121224 {ECO:0000313|Proteomes:UP000009046};
RN   [1] {ECO:0000313|EMBL:EEB14351.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=USDA {ECO:0000313|EMBL:EEB14351.1};
RA   Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA   Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA   Amedeo P., Strausberg R.;
RT   "Annotation of Pediculus humanus corporis strain USDA.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EEB14351.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=USDA {ECO:0000313|EMBL:EEB14351.1};
RG   The Human Body Louse Genome Consortium;
RA   Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT   "The genome of the human body louse.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Proteomes:UP000009046, ECO:0000313|VectorBase:PHUM294210-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USDA {ECO:0000313|Proteomes:UP000009046,
RC   ECO:0000313|VectorBase:PHUM294210-PA};
RX   PubMed=20566863; DOI=10.1073/pnas.1003379107;
RA   Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A.,
RA   Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E.,
RA   Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A.,
RA   Veenstra J.A., Walenz B., Tubio J.M., Ribeiro J.M., Rozas J.,
RA   Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L.,
RA   Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M.,
RA   Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P.,
RA   Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M.,
RA   Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F.,
RA   Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G.,
RA   Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C.,
RA   Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L.,
RA   Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C.,
RA   Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M.,
RA   Pittendrigh B.R.;
RT   "Genome sequences of the human body louse and its primary endosymbiont
RT   provide insights into the permanent parasitic lifestyle.";
RL   Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010).
RN   [4] {ECO:0000313|VectorBase:PHUM294210-PA}
RP   IDENTIFICATION.
RC   STRAIN=USDA {ECO:0000313|VectorBase:PHUM294210-PA};
RG   VectorBase;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   EMBL; DS235281; EEB14351.1; -; Genomic_DNA.
DR   RefSeq; XP_002427089.1; XM_002427044.1.
DR   STRING; 121225.PHUM294210-PA; -.
DR   EnsemblMetazoa; PHUM294210-RA; PHUM294210-PA; PHUM294210.
DR   GeneID; 8229722; -.
DR   KEGG; phu:Phum_PHUM294210; -.
DR   VectorBase; PHUM294210-RA; PHUM294210-PA; PHUM294210.
DR   CTD; 8229722; -.
DR   InParanoid; E0VLU5; -.
DR   KO; K11430; -.
DR   OMA; VYNYTPC; -.
DR   PhylomeDB; E0VLU5; -.
DR   Proteomes; UP000009046; Partially assembled WGS sequence.
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:UniProtKB-EC.
DR   CDD; cd00167; SANT; 1.
DR   InterPro; IPR026489; CXC_dom.
DR   InterPro; IPR001005; SANT/Myb.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR033467; Tesmin/TSO1-like_CXC.
DR   Pfam; PF00856; SET; 1.
DR   SMART; SM01114; CXC; 1.
DR   SMART; SM00717; SANT; 2.
DR   SMART; SM00317; SET; 1.
DR   PROSITE; PS51633; CXC; 1.
DR   PROSITE; PS50280; SET; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000009046};
KW   Methyltransferase {ECO:0000313|EMBL:EEB14351.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW   Transferase {ECO:0000313|EMBL:EEB14351.1}.
FT   DOMAIN      487    588       CXC. {ECO:0000259|PROSITE:PS51633}.
FT   DOMAIN      595    710       SET. {ECO:0000259|PROSITE:PS50280}.
SQ   SEQUENCE   729 AA;  83890 MW;  7F241EC31E058EEA CRC64;
     MAKSKVNAEW KKRVKSEYLR LRQQKRYKRA DEVKVAWNSN RTALNHNLSL EEKRWLESKN
     YWVCMKNPPP HADSMKRAEI QISDGETISF PIKTIYAVTP IPTMYTWAPI QQNFMVEDET
     VLHNIPYMGD EVLEHDGTFI EELIKNYDGK VHGDRETGFI DDQIFLELVN TLIQYQDKDL
     IDKDTEKDKE KDVEKEKDKR DTKKAFPVFE IFQAIALMFP DKGSPEELRD KYIELSERLD
     PNAVPPECTP NIDGPVAENV PREQTMHSFH TLFCRRCFKY DCFLHRLQAC HPGPNLQKRK
     PPDLGPFDQP CSPDCYMLME GMKEKLAAAA VTRDKETGIT EENESGNKPR RVKKQTSVDS
     GNEASSEDSN DSNRFHKDFK TSGKTSPNIM NMNQEGTSTG PFSLLGLIPS NQAEEWTGSD
     QSLFRALHKI FLNNYCAIKD CMLTKTCRQI YEFAQKEAAE LLPAESMKDY TPPRKKKKKH
     RLWSVHCRKI QLKKDSSSNH VYNFTPCDHP NLSCDAMCPC IGAQNFCEKF CQCSSDCQNR
     FPGCRCKAQC NTKQCPCYLA VRECDPDLCQ TCGADQFQIA NISCKNVSVQ RGLHKHLLMA
     PSDVAGWGIF LKESAQKNEF ISEYCGEIIS QDEADRRGKV YDKYMCSFLF NLNNDFVVDA
     TRKGNKIRFA NHSINPNCYA KVMMVNGDHR IGIFAKRAIQ PGEELFFDYR YGPTEQLKFV
     GIEREMEFL
//
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