ID E1BJX2_BOVIN Unreviewed; 241 AA.
AC E1BJX2;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=glutathione transferase {ECO:0000256|ARBA:ARBA00012452};
DE EC=2.5.1.18 {ECO:0000256|ARBA:ARBA00012452};
GN Name=GSTT4 {ECO:0000313|Ensembl:ENSBTAP00000000195.3};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000000195.3, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000000195.3, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000000195.3,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000000195.3}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000000195.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GST superfamily. Theta family.
CC {ECO:0000256|ARBA:ARBA00009899}.
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DR RefSeq; NP_001193552.1; NM_001206623.1.
DR AlphaFoldDB; E1BJX2; -.
DR SMR; E1BJX2; -.
DR STRING; 9913.ENSBTAP00000000195; -.
DR PaxDb; 9913-ENSBTAP00000000195; -.
DR Ensembl; ENSBTAT00000000195.4; ENSBTAP00000000195.3; ENSBTAG00000000170.4.
DR GeneID; 506093; -.
DR KEGG; bta:506093; -.
DR CTD; 25774; -.
DR VEuPathDB; HostDB:ENSBTAG00000000170; -.
DR eggNOG; KOG0867; Eukaryota.
DR GeneTree; ENSGT00940000161301; -.
DR HOGENOM; CLU_011226_2_0_1; -.
DR InParanoid; E1BJX2; -.
DR OMA; IQQPMSK; -.
DR TreeFam; TF325759; -.
DR Proteomes; UP000009136; Chromosome 17.
DR Bgee; ENSBTAG00000000170; Expressed in spermatid and 93 other cell types or tissues.
DR ExpressionAtlas; E1BJX2; baseline.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0004364; F:glutathione transferase activity; IBA:GO_Central.
DR GO; GO:0006749; P:glutathione metabolic process; IBA:GO_Central.
DR CDD; cd03183; GST_C_Theta; 1.
DR CDD; cd03050; GST_N_Theta; 1.
DR Gene3D; 1.20.1050.10; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR040079; Glutathione_S-Trfase.
DR InterPro; IPR004045; Glutathione_S-Trfase_N.
DR InterPro; IPR004046; GST_C.
DR InterPro; IPR040077; GST_C_Theta.
DR InterPro; IPR040075; GST_N_Theta.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43917; -; 1.
DR PANTHER; PTHR43917:SF13; GLUTATHIONE S-TRANSFERASE THETA-4-RELATED; 1.
DR Pfam; PF00043; GST_C; 1.
DR Pfam; PF13417; GST_N_3; 1.
DR SFLD; SFLDS00019; Glutathione_Transferase_(cytos; 1.
DR SFLD; SFLDG00358; Main_(cytGST); 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS50405; GST_CTER; 1.
DR PROSITE; PS50404; GST_NTER; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT DOMAIN 1..82
FT /note="GST N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50404"
FT DOMAIN 88..218
FT /note="GST C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50405"
SQ SEQUENCE 241 AA; 28076 MW; 90444783790104C1 CRC64;
MGLELYLDLL SPSCRAVYIF ARKNSIPFDF QFVDLLKGHH HSREYIEINP LRKLPSLRDG
KFILSESVAI LFYLCRKYSA PSHWYPPDLH MRARVDEFMA WQHTAIQLPM NKILWMKLLI
PMITGDEVPA EKTEQMLAEV KNNLKLFEEK FLQDKMFITG DNISLADLVA LVEMMQPMAG
NHNVFLNSAK LAEWRMRVEL AIGSTLFCEA HDRLVKLAEW DCSTLDPMVK ERICDLLQKF
K
//
