ID E1UR23_BACAS Unreviewed; 412 AA.
AC E1UR23;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 01-MAY-2013, entry version 19.
DE RecName: Full=3-oxoacyl-[acyl-carrier-protein] synthase 2;
DE EC=2.3.1.179;
GN Name=fabF; OrderedLocusNames=BAMF_1207;
OS Bacillus amyloliquefaciens (strain ATCC 23350 / DSM 7 / BCRC 11601 /
OS NBRC 15535 / NRRL B-14393).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=692420;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DSM7;
RX DOI=10.1099/ijs.0.023267-0 ;
RA Borriss R., Chen X., Rueckert C., Blom J., Becker A., Baumgarth B.,
RA Fan B., Pukall R., Schumann P., Sproer C., Junge H., Vater J.,
RA Puhler A., Klenk H.P.;
RT "Relationship of Bacillus amyloliquefaciens clades associated with
RT strains DSM7T and FZB42: a proposal for Bacillus amyloliquefaciens
RT subsp. amyloliquefaciens subsp. nov. and Bacillus amyloliquefaciens
RT subsp. plantarum subsp. nov. based on their discriminating complete
RT genome sequences.";
RL Int. J. Syst. Evol. Microbiol. 0:0-0(2010).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23350 / DSM 7 / BCRC 11601 / NBRC 15535 / NRRL B-14393;
RX PubMed=21262282; DOI=10.1016/j.jbiotec.2011.01.006;
RA Ruckert C., Blom J., Chen X., Reva O., Borriss R.;
RT "Genome sequence of B. amyloliquefaciens type strain DSM7(T) reveals
RT differences to plant-associated B. amyloliquefaciens FZB42.";
RL J. Biotechnol. 155:78-85(2011).
CC -!- FUNCTION: Catalyzes the condensation reaction of fatty acid
CC synthesis by the addition to an acyl acceptor of two carbons from
CC malonyl-ACP (By similarity).
CC -!- CATALYTIC ACTIVITY: (Z)-hexadec-11-enoyl-[acyl-carrier-protein] +
CC malonyl-[acyl-carrier-protein] = (Z)-3-oxooctadec-13-enoyl-[acyl-
CC carrier-protein] + CO(2) + [acyl-carrier-protein].
CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC -!- SIMILARITY: Belongs to the beta-ketoacyl-ACP synthases family.
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DR EMBL; FN597644; CBI42333.1; -; Genomic_DNA.
DR RefSeq; YP_003919803.1; NC_014551.1.
DR EnsemblBacteria; CBI42333; CBI42333; BAMF_1207.
DR GeneID; 9778758; -.
DR KEGG; bao:BAMF_1207; -.
DR PATRIC; 42471438; VBIBacAmy172706_1297.
DR HOGENOM; HOG000060166; -.
DR KO; K09458; -.
DR BioCyc; BAMY692420:GHU2-735-MONOMER; -.
DR UniPathway; UPA00094; -.
DR GO; GO:0033817; F:beta-ketoacyl-acyl-carrier-protein synthase II activity; IEA:EC.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR017568; 3-oxoacyl-ACP_synth-2.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR016038; Thiolase-like_subgr.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR PIRSF; PIRSF000447; KAS_II; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR TIGRFAMs; TIGR03150; fabF; 1.
DR PROSITE; PS00606; B_KETOACYL_SYNTHASE; 1.
PE 3: Inferred from homology;
KW Acyltransferase; Complete proteome; Fatty acid biosynthesis;
KW Lipid biosynthesis; Transferase.
SQ SEQUENCE 412 AA; 43771 MW; 024D2ACCE7438D03 CRC64;
MSKKRVVVTG LGALSPLGND AETSWKNAIS GVSGIGPITR VESDEYPAKV AAELKDFNVE
NYMDKKEARK MDRFTQYAVV AAKMAVEDAG LNITEEIAPR VGVWVGSGIG GLETLESQFE
IFLTKGPRRV SPFFVPMMIP DMATGQISIA LGAKGVNSCT VTACATGTNS IGDAFKVIQR
GDADAMISGG TEAPLTRMSF AGFSANKALS TNPDPKTASR PFDKNRDGFV MGEGAGIVVL
EELEHALARG AKIYGEIVGY GSTGDAYHIT APAQDGEGGA RAMQEAIKDA GIKPEEIDYI
NAHGTSTYYN DKYETKAIKT VFGDHAYKLA VSSTKSMTGH LLGAAGGIEA IFSVMAIKDG
IIPPTINIET PDEECDLDYV PDKAREQDVN IVLSNSLGFG GHNATLIFKK YQ
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