ID E3EJF7_PAEPS Unreviewed; 529 AA.
AC E3EJF7;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Acyl--CoA ligase {ECO:0000313|EMBL:ADO56507.1};
GN Name=acsA1 {ECO:0000313|EMBL:ADO56507.1};
GN ORFNames=PPSC2_11910 {ECO:0000313|EMBL:ADO56507.1};
OS Paenibacillus polymyxa (strain SC2) (Bacillus polymyxa).
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=886882 {ECO:0000313|EMBL:ADO56507.1, ECO:0000313|Proteomes:UP000006868};
RN [1] {ECO:0000313|EMBL:ADO56507.1, ECO:0000313|Proteomes:UP000006868}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC2 {ECO:0000313|EMBL:ADO56507.1,
RC ECO:0000313|Proteomes:UP000006868};
RX PubMed=21037012; DOI=10.1128/JB.01234-10;
RA Ma M., Wang C., Ding Y., Li L., Shen D., Jiang X., Guan D., Cao F.,
RA Chen H., Feng R., Wang X., Ge Y., Yao L., Bing X., Yang X., Li J., Du B.;
RT "Complete genome sequence of Paenibacillus polymyxa SC2, a strain of plant
RT growth-promoting Rhizobacterium with broad-spectrum antimicrobial
RT activity.";
RL J. Bacteriol. 193:311-312(2011).
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; CP002213; ADO56507.1; -; Genomic_DNA.
DR RefSeq; WP_013371112.1; NC_014622.2.
DR AlphaFoldDB; E3EJF7; -.
DR STRING; 1406.LK13_24230; -.
DR KEGG; ppm:PPSC2_11910; -.
DR PATRIC; fig|886882.15.peg.2523; -.
DR eggNOG; COG0365; Bacteria.
DR HOGENOM; CLU_000022_59_10_9; -.
DR OrthoDB; 9757771at2; -.
DR Proteomes; UP000006868; Chromosome.
DR GO; GO:0016878; F:acid-thiol ligase activity; IEA:UniProt.
DR GO; GO:0016405; F:CoA-ligase activity; IEA:UniProt.
DR CDD; cd05972; MACS_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43605:SF10; ACYL-COA SYNTHETASE MEDIUM CHAIN FAMILY MEMBER 3; 1.
DR PANTHER; PTHR43605; ACYL-COENZYME A SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ADO56507.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006868}.
FT DOMAIN 24..386
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 436..514
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 529 AA; 59100 MW; D53398FF7A33164E CRC64;
MTDQQQWLAP EYYNMTSEME HHEAGKTALK WLSETGEYEE ITYGELLKKA NRLAGGLASL
GFNKGDRVLV VVPRRIIAYV IYLACLKLGL AVIPSSEMLR AKDIAYRLRH SEARAVIAWT
DVTSEVDKIS DDLPALDYRI VVPGDRTVGA QGWLVLDELM EGQEDIFEAV KTHRDDMAIL
AYTSGTTGNP KGVVHSHGWG YAHLRITSPW LDIRASDIVW ATAAPGWQKW IWSPFLSVLG
NGATGFVYNG PFRPGRYLQL LQQYGVQVLC CTPTEYRIMA KTAGLDQYDL SRLRSAVSAG
EPLNQEVINK FQEQFNITIR DGYGQTESTL IIGNLRDVPL RTGSMGKSIA PGLVEVVDED
GIPLAPGQVG DIAVRADLPA LFHTYYHDPE RKLASVHGDY FVTGDRARKD EDGYFWFEGR
GDDIIISSGY TIGPFEVEEA LMKHDSVQEC AAVASPDEVR GHVVKAYIVL KAGIEGSPEL
VKELQHHVKT WTAPYKYPRK IEFIEELPKT SSGKIRRVEL RELEKQSVL
//
