ID E3FGR1_STIAD Unreviewed; 3098 AA.
AC E3FGR1;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=LgrB-like linear gramicidin synthetase subunit B protein {ECO:0000313|EMBL:ADO72770.1};
GN OrderedLocusNames=STAUR_4992 {ECO:0000313|EMBL:ADO72770.1};
OS Stigmatella aurantiaca (strain DW4/3-1).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Archangiaceae; Stigmatella.
OX NCBI_TaxID=378806 {ECO:0000313|EMBL:ADO72770.1, ECO:0000313|Proteomes:UP000001351};
RN [1] {ECO:0000313|EMBL:ADO72770.1, ECO:0000313|Proteomes:UP000001351}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DW4/3-1 {ECO:0000313|EMBL:ADO72770.1,
RC ECO:0000313|Proteomes:UP000001351};
RX PubMed=21037205; DOI=10.1093/molbev/msq292;
RA Huntley S., Hamann N., Wegener-Feldbrugge S., Treuner-Lange A., Kube M.,
RA Reinhardt R., Klages S., Muller R., Ronning C.M., Nierman W.C.,
RA Sogaard-Andersen L.;
RT "Comparative genomic analysis of fruiting body formation in Myxococcales.";
RL Mol. Biol. Evol. 28:1083-1097(2011).
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
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DR EMBL; CP002271; ADO72770.1; -; Genomic_DNA.
DR STRING; 378806.STAUR_4992; -.
DR KEGG; sur:STAUR_4992; -.
DR eggNOG; COG0318; Bacteria.
DR eggNOG; COG1020; Bacteria.
DR HOGENOM; CLU_225793_0_0_7; -.
DR Proteomes; UP000001351; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:InterPro.
DR CDD; cd12115; A_NRPS_Sfm_like; 1.
DR CDD; cd19534; E_NRPS; 1.
DR CDD; cd05931; FAAL; 1.
DR CDD; cd19531; LCL_NRPS-like; 2.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 3.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 3.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 3.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR001466; Beta-lactam-related.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR040097; FAAL/FAAC.
DR InterPro; IPR010060; NRPS_synth.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR NCBIfam; TIGR01720; NRPS-para261; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 2.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF00144; Beta-lactamase; 1.
DR Pfam; PF00668; Condensation; 3.
DR Pfam; PF00550; PP-binding; 3.
DR SMART; SM00823; PKS_PP; 2.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR SUPFAM; SSF47336; ACP-like; 3.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 6.
DR PROSITE; PS00455; AMP_BINDING; 2.
DR PROSITE; PS50075; CARRIER; 3.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 611..688
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1667..1742
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2231..2305
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 3098 AA; 341791 MW; 3C68895EF5D814A6 CRC64;
MPLNRQPLTL IELLEEKASL TPDQPLFTFQ EETEGEEKTL SYGELRYRAL TIARSVQALA
APGERALLLY PPGLEYIAGF FGCLYAGMVA VPAYPPDPLR LNRTLPRLRA MIQDAQAKVV
LTTSFILSMG ESLFEQEPDF KNLHWIATDD LPKGAPDRWV QPSVSGNTLA FLQYTSGSTG
APKGVMLTHD NLLCNLEMIA HTFQIRSDSV CVIWLPPYHD MGLIGGILEP VYTGMRTTLM
SPMSFLKNPF RWLDTISRLK ATVSGGPNFA FDLCVRKVTA EQRQRLDLSH WKVAFSGAEP
IRPETLDRFT QTFETCGFRR KAFFPCYGLA EATLIVSGGE VPEPPILCSL RASALEQGQA
VEAPSGELDS RTLVGCGQTV PNQEILIVDP VSSVPCPPGK VGEIWVCGPS VAQGYWQKPT
ETGQIFQARP ASGGERVYLR TGDLGFLKER ELFVTGRQKD LIIIRGRNHF PQDLELTAEQ
SHPSLRPGCS AAFSVDWEGE EKLVLVQEVD VRKAGDLRAQ LDVCKAAATA LRQRLAEVHE
VQLHALALIE PGTIFKTSSG KIQRSACREA FLSGALQTVL KWETSNRAVQ PRAVHEAAPP
PLLTAAPTDL STEEGLQSWL VAHVAKQLRI PATSLDPAMP LTGYGLDSLA AVELAHSLEK
GLGFPISMEL LLQGSSLAQL ARQFFTQRPQ EAKDHAPLVS QLPRNNPLPL SYAQQRLWFL
DQLEPGSPRY IIPAAVRIEG ALNVPLLEHS FLLLALRHEP LRTTFLSSPQ GPSQLISPSS
SFQLQHFDLR SLPPHLRDAR LLSLCSELSL LPFSLSQGPL LRACLLHLDE HLFVLFLSMH
HIISDGWSMG VLVRELASLY QSLLHSAPST LPDLPFQYAD FASWQRSWLL GPRLLSQLAW
WREHLCGAPL SLHLPTDFPR PPVLSSRGAS VPVLLPASLS RSLHSLCLRE GVTPFMALIA
VFQLLLSRYS AQDDICVGFP IANRNLPSLE GLIGFFANTL LLRSRLPPDS SFLQLLSQVR
SSSLGAYAHQ DVPFDKLVEA MNPERDLSRS PLFQAMFSLQ NTPVLELDEV HLHLRQLELE
SQTCLFDLML SLEDTGTGFA GKLHYSTDLF TAATASQMAR HFLVLMEGLL NNPDQHLSEV
SLLTPQERQQ LLEEWSGTAP LASSLCLHHL FEAQVARSPD AIALVVDSTR LSYRELNRRA
NQLAHCLQAL GASPDVPIGL CLQRSTDMVI GLLAILKAGA AYVPLDPAYP AERLIYSFQD
AGASLLVTQD TLRHLLPIAG AKTVCLDSGW EPISRESTDN PRSSVLPSNL AYVLYTSGST
GRPKGVAIEH HNAAVFIQWS LNCFSAQQLA GVLASTSICF DLSIFELFAP LCSGGTVLLA
SNALALPSLP AAQEVTLINT VPSAIAELAR TNAIPSSIHT LNLAGEPLSG SLVRALYSLP
SIQHVFNLYG PTEDTTYSTF TLIPKDASSE PTIGRPISGT RAYVLDRQLH LVPRGVPGEL
YLSGSGLARG YINRPELTAE RFLPNPFSTE PGSRLYKTGD LARFAVDGNL EYLGRIDHQV
KIRGFRIELG EIESILLTQP GLHQAAVLAH EEAPGDKRLV AYVVAARNHS FTPAELRRLL
KERLPDYMVP SAFVLLDALP LTPNGKLDRK ALPRPGAPSL EQKGFVPPHT QTEKALAEMW
CELLNIDRVG IQDHFFELGG HSLLASQVIS RIRSALGVEL PLRSLFESPS LESFATAVDS
ALNSPQAPQL PQRLPPQSRP GPLPLSYAQQ RLWFLDQLEP GSPRYIIPAA VRIEGALNVP
LLEHSFLLLA LRHEPLRTTF LSSPQGPSQL ISLSSSFQLQ HFDLRSLPPH LRDARLLSLC
SELSLLPFSL SQGPLLRACL LHLDEHLFVL FLSMHHIISD GWSMGVLVRE LASLYQSLLH
SAPSTLPDLP FQYADFASWQ RSWLLGPRLL SQLAWWREHL RGAPLSLHLP TDFPRPPVLS
SRGASVPVLL PASLSRSLHS LCLREGVTPF MALIAVFQLL LSRYSAQDDI CVGFPIANRN
LPSLEGLIGF FANTLLLRSR LPPDSSFLQL LSQVRSSSLG AYAHQDVPFD KLVEAMNPER
DLSRSPLFQA MFSLQNTPVL ELALPELVLH PMELPSQTAK FELLLSLSED TEGFSGILEY
NTDLFTAATI SQMAEHFCVL LEDVLAHPER RLDQLSPLFS PEEHPLLVKR HDRELPQQAL
TEPPPSSVAA LPLSSIHLTL VDIWKEVLSL QHVGIHDDFF TRGGNSISSI LVVARLQEAG
LHLSPDQIFQ KRTIAELAPL VTSARKTEGQ GEITGALPLT PIQRWFFDTW EQHAHHFNQA
VMLEVLEDIE AAVLEGALQK LLEHHDALRL RFERTGDGWR QENGGAGRPI ALKQVDVSGL
TQEAQTQTLA KVAEEEQESF DLAEGQLLRA VLFHRGQGRT GRLLLVIHHL GVDGLSWRTL
IEDLEKAYKH LSSGGEAVLG TKTTSFKTWA EHLELYAGTQ DVEEQLPYWE KQGQEEVGPL
PVDKAVGANT VVSEDRVTVR LEEEETRALL QEVPTAYGTR VEEVLLAALT ATMGRWTGLD
RISVSMEGHG REELFEDVDL SRTVGWFTSL YPMVLDTGKA ERPEDKLQAV SNRLKGLPMK
GLGYGLLRYL GRDEIVKKLE RLSSPELLFN YLGEFDASAS RLSMFRPTRE ETGPARSREG
LRSHLLEVNG LVFDWRLELT WSYSQNRHER ATIERLAQGF MSELRGFIDH QKTAIAHKNT
PANESLSVRL EQVTQGLIHD QQMLGTALLV ELADRRRVHM AKGTSDPAGT PYTQTTRVLI
GSLTKMFTAV AILQLVEDGR LSLDATVNEW LPWLMRGKAI TLRDLLAHTS GLPDYLSRLT
LLDTAKPCSP RSLVELAEHE PAVPPGHYSN TNYIVLGLLL EALTGSTWEE EISRRILEPL
GLIRTTPLTE SPPEDLVGAW KRGDDGWKDI RPVWHPSCGW AAGGMISTTE ELVTFGRALF
SGALFKSPDT LAAMRSYSVS STPHMAVGVE HEMGLCLHLF RVAGITLEGH LGERPGYSAV
LLHDPETQAI VAATANTHGA LTAFAGVKAL EAVRRATS
//
