ID E3G7U3_ENTCS Unreviewed; 229 AA.
AC E3G7U3;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 01-MAY-2013, entry version 17.
DE SubName: Full=Uracil-DNA glycosylase;
GN OrderedLocusNames=Entcl_1167;
OS Enterobacter cloacae (strain SCF1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex.
OX NCBI_TaxID=701347;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCF1;
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N.,
RA Mikhailova N., DeAngelis K., Arkin A.P., Chivian D., Edwards B.,
RA Woo H., Hazen T.C., Woyke T.;
RT "Complete sequence of Enterobacter cloacae SCF1.";
RL Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Excises uracil residues from the DNA which can arise as
CC a result of misincorporation of dUMP residues by DNA polymerase or
CC due to deamination of cytosine (By similarity).
CC -!- CATALYTIC ACTIVITY: Hydrolyzes single-stranded DNA or mismatched
CC double-stranded DNA and polynucleotides, releasing free uracil.
CC -!- SIMILARITY: Belongs to the uracil-DNA glycosylase family.
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DR EMBL; CP002272; ADO47434.1; -; Genomic_DNA.
DR RefSeq; YP_003940718.1; NC_014618.1.
DR EnsemblBacteria; ADO47434; ADO47434; Entcl_1167.
DR GeneID; 9906199; -.
DR KEGG; esc:Entcl_1167; -.
DR PATRIC; 42596383; VBIEntClo171306_1178.
DR HOGENOM; HOG000229528; -.
DR KO; K03648; -.
DR OMA; AGKEIYP; -.
DR BioCyc; ECLO701347:GH9V-1194-MONOMER; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004844; F:uracil DNA N-glycosylase activity; IEA:HAMAP.
DR GO; GO:0006284; P:base-excision repair; IEA:HAMAP.
DR Gene3D; 3.40.470.10; -; 1.
DR HAMAP; MF_00148; UDG; 1; -.
DR InterPro; IPR018085; Ura-DNA_Glyclase_AS.
DR InterPro; IPR002043; Ura_DNA_glycsylse.
DR InterPro; IPR005122; Uracil-DNA_glycosylase-like.
DR PANTHER; PTHR11264; PTHR11264; 1.
DR Pfam; PF03167; UDG; 1.
DR SMART; SM00986; UDG; 1.
DR SUPFAM; SSF52141; UDNA_glycsylseSF; 1.
DR TIGRFAMs; TIGR00628; ung; 1.
DR PROSITE; PS00130; U_DNA_GLYCOSYLASE; 1.
PE 3: Inferred from homology;
KW Complete proteome; DNA damage; DNA repair; Glycosidase; Hydrolase.
SQ SEQUENCE 229 AA; 25435 MW; 03B5C96AE7887C0A CRC64;
MTTPLTWHDV LAGEKQQPYF LNTLTTVANE RQSGITVYPP QKDVFNAFRY TELGDVKVVI
LGQDPYHGPG QAHGLAFSVR PGIATPPSLL NMYKELEGTI PGFSRPPHGY LESWARQGVL
LLNTVLTVRA GQAHSHASLG WETFTDKVIS LINEHRQGVV FLLWGSHAQK KGAIIDRQRH
HVLKAPHPSP LSAHRGFFGC NHFVLANQWL AEQGEAPIDW MPVLPAESE
//
