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Database: UniProt/TrEMBL
Entry: E4N6M6_KITSK
LinkDB: E4N6M6_KITSK
Original site: E4N6M6_KITSK 
ID   E4N6M6_KITSK            Unreviewed;       603 AA.
AC   E4N6M6;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   25-OCT-2017, entry version 37.
DE   SubName: Full=Putative sialidase {ECO:0000313|EMBL:BAJ26857.1};
DE            EC=3.2.1.18 {ECO:0000313|EMBL:BAJ26857.1};
GN   OrderedLocusNames=KSE_10220 {ECO:0000313|EMBL:BAJ26857.1};
OS   Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC
OS   A-0304 / NBRC 14216 / KM-6054) (Streptomyces setae).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Kitasatospora.
OX   NCBI_TaxID=452652 {ECO:0000313|EMBL:BAJ26857.1, ECO:0000313|Proteomes:UP000007076};
RN   [1] {ECO:0000313|EMBL:BAJ26857.1, ECO:0000313|Proteomes:UP000007076}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 /
RC   KM-6054 {ECO:0000313|Proteomes:UP000007076};
RX   PubMed=21059706; DOI=10.1093/dnares/dsq026;
RA   Ichikawa N., Oguchi A., Ikeda H., Ishikawa J., Kitani S., Watanabe Y.,
RA   Nakamura S., Katano Y., Kishi E., Sasagawa M., Ankai A., Fukui S.,
RA   Hashimoto Y., Kamata S., Otoguro M., Tanikawa S., Nihira T.,
RA   Horinouchi S., Ohnishi Y., Hayakawa M., Kuzuyama T., Arisawa A.,
RA   Nomoto F., Miura H., Takahashi Y., Fujita N.;
RT   "Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary
RT   snapshot of the family Streptomycetaceae.";
RL   DNA Res. 17:393-406(2010).
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DR   EMBL; AP010968; BAJ26857.1; -; Genomic_DNA.
DR   STRING; 452652.KSE_10220; -.
DR   CAZy; GH33; Glycoside Hydrolase Family 33.
DR   EnsemblBacteria; BAJ26857; BAJ26857; KSE_10220.
DR   KEGG; ksk:KSE_10220; -.
DR   PATRIC; fig|452652.3.peg.1015; -.
DR   eggNOG; ENOG4108478; Bacteria.
DR   eggNOG; COG4409; LUCA.
DR   KO; K01186; -.
DR   OMA; SHAANIY; -.
DR   OrthoDB; POG091H0EBR; -.
DR   BioCyc; KSET452652:GJFD-1006-MONOMER; -.
DR   Proteomes; UP000007076; Chromosome.
DR   GO; GO:0052794; F:exo-alpha-(2->3)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052795; F:exo-alpha-(2->6)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052796; F:exo-alpha-(2->8)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; PTHR10628; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; SSF50939; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007076};
KW   Glycosidase {ECO:0000313|EMBL:BAJ26857.1};
KW   Hydrolase {ECO:0000313|EMBL:BAJ26857.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007076};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     31       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        32    603       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003186400.
FT   DOMAIN      289    578       Sialidase. {ECO:0000259|Pfam:PF13088}.
SQ   SEQUENCE   603 AA;  61352 MW;  A6A33C55E9DDEACD CRC64;
     MALSPPPARA LLAVGALTLA ALPLGATGAS AATPVGQSAV VSQDCASGGR IQQTVVNNTA
     TPTTFTLTWP GNGSWTATVA AFDSGHFYFT KPSGTAYTFR TTTPQGYDST VSGTLDCANA
     LAANVSLECP RDADGSLPAG HRLRVTLDNR TAAAQTFTVA WPGRAYSPWT VTVPAMSGDS
     SLYWTLPNGT PYTFNLSVAG SSWTDTESGT ASCGLAAGTP GMNAQTVLTT ATPISGVNTL
     AADGVSYTTT TATAKSVRIP ALAQTASGTV IATADARIDG GADLGGGTNN IQVVMVRSTD
     GGVTFSAPRI IAHPPTTKEG YGDSSLLVDR ATGRVFCFFT YSPKAGVGYY GSTAGDTSAT
     ATTNTHVRYV TSDDDGATWS TPVDLNPSVR DGSWAGMFAS SGHGIQLASG RLVQPMVYRD
     AAGDHAANLY SDDHGASWHA GGSAATGVNE SKAIQRGTGK VVQNMRSNAG GNRWYATAAG
     GSDVAGGFGT AWNSGLLDPG CNGDEVSYLR PTDTDAAGNP LLSSTAVLSN TATANNSTRQ
     DLTVRISQDD GASWPHRALL KAGPSGYSSA AVLDDGTVAD LYEIGGTGGI VYTNFTTAWV
     TGS
//
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