GenomeNet

Database: UniProt/TrEMBL
Entry: E4NGW1_KITSK
LinkDB: E4NGW1_KITSK
Original site: E4NGW1_KITSK 
ID   E4NGW1_KITSK            Unreviewed;      1250 AA.
AC   E4NGW1;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   28-MAR-2018, entry version 42.
DE   SubName: Full=Putative 2-oxoglutarate dehydrogenase E1 component {ECO:0000313|EMBL:BAJ30741.1};
DE            EC=1.2.4.2 {ECO:0000313|EMBL:BAJ30741.1};
GN   OrderedLocusNames=KSE_49630 {ECO:0000313|EMBL:BAJ30741.1};
OS   Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC
OS   A-0304 / NBRC 14216 / KM-6054) (Streptomyces setae).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Kitasatospora.
OX   NCBI_TaxID=452652 {ECO:0000313|EMBL:BAJ30741.1, ECO:0000313|Proteomes:UP000007076};
RN   [1] {ECO:0000313|EMBL:BAJ30741.1, ECO:0000313|Proteomes:UP000007076}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 /
RC   KM-6054 {ECO:0000313|Proteomes:UP000007076};
RX   PubMed=21059706; DOI=10.1093/dnares/dsq026;
RA   Ichikawa N., Oguchi A., Ikeda H., Ishikawa J., Kitani S., Watanabe Y.,
RA   Nakamura S., Katano Y., Kishi E., Sasagawa M., Ankai A., Fukui S.,
RA   Hashimoto Y., Kamata S., Otoguro M., Tanikawa S., Nihira T.,
RA   Horinouchi S., Ohnishi Y., Hayakawa M., Kuzuyama T., Arisawa A.,
RA   Nomoto F., Miura H., Takahashi Y., Fujita N.;
RT   "Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary
RT   snapshot of the family Streptomycetaceae.";
RL   DNA Res. 17:393-406(2010).
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AP010968; BAJ30741.1; -; Genomic_DNA.
DR   RefSeq; WP_014138040.1; NC_016109.1.
DR   STRING; 452652.KSE_49630; -.
DR   EnsemblBacteria; BAJ30741; BAJ30741; KSE_49630.
DR   KEGG; ksk:KSE_49630; -.
DR   PATRIC; fig|452652.3.peg.4957; -.
DR   eggNOG; ENOG4105C7P; Bacteria.
DR   eggNOG; COG0508; LUCA.
DR   eggNOG; COG0567; LUCA.
DR   KO; K00164; -.
DR   OMA; IDMVCYR; -.
DR   OrthoDB; POG091H03SK; -.
DR   BioCyc; KSET452652:G1H62-5007-MONOMER; -.
DR   Proteomes; UP000007076; Chromosome.
DR   GO; GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:UniProtKB-EC.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:InterPro.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   Gene3D; 3.30.559.10; -; 1.
DR   InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR   InterPro; IPR032106; 2-oxogl_dehyd_N.
DR   InterPro; IPR011603; 2oxoglutarate_DH_E1.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR001017; DH_E1.
DR   InterPro; IPR031717; KGD_C.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   PANTHER; PTHR23152; PTHR23152; 1.
DR   Pfam; PF00198; 2-oxoacid_dh; 1.
DR   Pfam; PF16078; 2-oxogl_dehyd_N; 1.
DR   Pfam; PF00676; E1_dh; 1.
DR   Pfam; PF16870; OxoGdeHyase_C; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   PIRSF; PIRSF000157; Oxoglu_dh_E1; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; SSF52518; 2.
DR   TIGRFAMs; TIGR00239; 2oxo_dh_E1; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007076};
KW   Oxidoreductase {ECO:0000313|EMBL:BAJ30741.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007076}.
FT   DOMAIN      903   1096       Transket_pyr. {ECO:0000259|SMART:
FT                                SM00861}.
FT   COILED      814    834       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1250 AA;  136628 MW;  1BD5F0855AD26935 CRC64;
     MSPHQETPSS ASSTGFGPNE WLVDEIYQQY LQDPASVDRA WWDFFADYKP GTEVTPVTQA
     ATPVGAQPTP VAAPAAAAPA APAAPAPVAP APAQPVAAPA TLPAAPAAPA APPAPKAAAP
     AAAAPAKAAG GPEVIQLRGP AKAVASNMDA SLEVPTATSV RAVPAKLLID NRIVINNHLQ
     RARGGKVSFT HLIGYALVQA VKANPGMNHS YKVEDGKSYL VKPEHVNLGL AIDLVKPNGD
     RQLVVAAIKK ADTLDFFGFW QAYEDIVRRA RANKLTMDDF TGVTVSLTNP GGIGTVHSVP
     RLMQNQGTIV GVGAMEYPAE FQGSSPETLA RLGISKIMTL TSTYDHRVIQ GAASGEFLRS
     IHQLLLGANN FYDEVFESLR IPYEPVRWAT DVATTHDDEV NKTARVIELI HSYRVRGHLM
     ADTDPLEYMQ RKHPDLDVTT HGLTLWDLER EFAVGGFGGQ KMMKLRDILG LLRNTYCRTV
     GIEYMHIQDP AQRRWLQERL EKPYTKPERE EQLRILRRLN SAEAFETFLQ TKYVGQKRFS
     LEGGESLIPL LDATIDAAAE HRLDEAVIGM AHRGRLNVLA NIVGKPFGKI FGEFEGNLDP
     KSMHGSGDVK YHLGSEGTFT GLDGETIKVS LAANPSHLET VDPVVEGIAR AKQDILDFGG
     TTFPVLPIQI HGDAAFAGQG VVAETLNMSQ LRGYRTGGTV HVVVNNQVGF TAAPASSRSS
     MYCTDVARMI EAPIFHVNGD DPEAVVRVAR LAFEFRQQFH KDVVIDLICY RRRGHNEADN
     PSFTQPLMYD LIDKKRSVRK LYTEALIGRG DITMEEAEQA LQDFQGQLEK VFAEVREAVA
     APAPAEPGRP VADFPVSLQT GISAETVKRI AASQVNLPDW LTVHPRLLPQ LQRRAASIED
     DTIDWATGEA LAIGSLLMEG HPVRLAGQDS RRGTFGQRHA VLIDRNTGED YTPLMYLTED
     QARFTVYDSL LSEYAAMGFE YGYSLTRPNA LVMWEAQFGD FVNGAQTMVD EYIASAEQKW
     GQHSGVTLLL PHGMEGQGPD HSSARPERFL ALCAQDNMTV AMPTLPSNYF HLLRWQAHNP
     HHKPLIVFTP KSMLRLKAAA SAASEFLTGA FRPVIGDRTV DPAKVRKVVI TSGKFYYDLE
     AARTDRGVTD TAIVRVERLY PLPVAELQEE LARYGDDVQF VWAQEEPANQ GAWPFIAMNL
     VDHLQVVIGP TGGNARLRRV ARPASSAPAV GSAKRHTAEQ QALIEEVFTL
//
DBGET integrated database retrieval system