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Database: UniProt/TrEMBL
Entry: E4NS97_HALBP
LinkDB: E4NS97_HALBP
Original site: E4NS97_HALBP 
ID   E4NS97_HALBP            Unreviewed;       489 AA.
AC   E4NS97;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   09-JUL-2014, entry version 27.
DE   RecName: Full=Argininosuccinate lyase;
DE            Short=ASAL;
DE            EC=4.3.2.1;
DE   AltName: Full=Arginosuccinase;
GN   Name=argH; OrderedLocusNames=Hbor_01710; ORFNames=C499_11281;
OS   Halogeometricum borinquense (strain ATCC 700274 / DSM 11551 / JCM
OS   10706 / PR3).
OC   Archaea; Euryarchaeota; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halogeometricum.
OX   NCBI_TaxID=469382;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700274 / DSM 11551 / JCM 10706 / PR3, and PR 3;
RX   PubMed=21304651; DOI=10.4056/sigs.23264;
RA   Malfatti S., Tindall B.J., Schneider S., Fahnrich R., Lapidus A.,
RA   Labuttii K., Copeland A., Glavina Del Rio T., Nolan M., Chen F.,
RA   Lucas S., Tice H., Cheng J.F., Bruce D., Goodwin L., Pitluck S.,
RA   Anderson I., Pati A., Ivanova N., Mavromatis K., Chen A.,
RA   Palaniappan K., D'haeseleer P., Goker M., Bristow J., Eisen J.A.,
RA   Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P., Chain P.;
RT   "Complete genome sequence of Halogeometricum borinquense type strain
RT   (PR3).";
RL   Stand. Genomic Sci. 1:150-159(2009).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=DSM 11551;
RA   Becker E.A., Seitzer P., Tritt A., Larsen D., Yao A., Wu D.,
RA   Darling A., Eisen J.A., Facciotti M.T.;
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: 2-(N(omega)-L-arginino)succinate = fumarate +
CC       L-arginine.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-arginine biosynthesis; L-
CC       arginine from L-ornithine and carbamoyl phosphate: step 3/3.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the lyase 1 family. Argininosuccinate lyase
CC       subfamily.
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DR   EMBL; CP001690; ADQ65782.1; -; Genomic_DNA.
DR   EMBL; AOHT01000037; ELY26785.1; -; Genomic_DNA.
DR   RefSeq; YP_004035221.1; NC_014729.1.
DR   ProteinModelPortal; E4NS97; -.
DR   EnsemblBacteria; ADQ65782; ADQ65782; Hbor_01710.
DR   EnsemblBacteria; ELY26785; ELY26785; C499_11281.
DR   GeneID; 9991991; -.
DR   KEGG; hbo:Hbor_01710; -.
DR   HOGENOM; HOG000242744; -.
DR   KO; K01755; -.
DR   OMA; IRPRREI; -.
DR   BioCyc; HBOR469382:GCNS-171-MONOMER; -.
DR   UniPathway; UPA00068; UER00114.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004056; F:argininosuccinate lyase activity; IEA:UniProtKB-EC.
DR   GO; GO:0042450; P:arginine biosynthetic process via ornithine; IEA:InterPro.
DR   Gene3D; 1.10.275.10; -; 1.
DR   HAMAP; MF_00006; Arg_succ_lyase; 1.
DR   InterPro; IPR029419; Arg_succ_lyase_C.
DR   InterPro; IPR009049; Argininosuccinate_lyase.
DR   InterPro; IPR024083; Fumarase/histidase_N.
DR   InterPro; IPR000362; Fumarate_lyase_fam.
DR   InterPro; IPR022761; Fumarate_lyase_N.
DR   InterPro; IPR008948; L-Aspartase-like.
DR   PANTHER; PTHR11444; PTHR11444; 1.
DR   PANTHER; PTHR11444:SF3; PTHR11444:SF3; 1.
DR   Pfam; PF14698; ASL_C2; 1.
DR   Pfam; PF00206; Lyase_1; 1.
DR   PRINTS; PR00149; FUMRATELYASE.
DR   SUPFAM; SSF48557; SSF48557; 1.
DR   TIGRFAMs; TIGR00838; argH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis; Arginine biosynthesis; Complete proteome;
KW   Cytoplasm; Lyase.
SQ   SEQUENCE   489 AA;  51656 MW;  772887FC8564184C CRC64;
     MNEEGGDEGV VRRDRFSGGP ARGFMSSLAA DERIFAADVA VDRAHVVMLE EQEIVESDVA
     AEILAALDDV ESEGHAALPE GEDVHEAIET AVVEQVGPDG GKMHTARSRN DEVATCIRYR
     LREDLLDAIE ATLALREALV DAAEAEVETV MPGYTHLQPA QPTTVAHYLL SYEAAFARDT
     ARLLDAYDRT NQSPLGAAAF AGTPFDIDRE RTAELLGFDG VLRNSMDASS ARDFLLESVS
     ALATHATTLS GLAEDLVIFS NKGFVELSDD YASTSSIMPQ KVNPDTLELV RATAGDAASG
     LSGLLTTLKG LPRAYNRDLQ RATPHAWDAV DSVSEATAVV AGAVSSASWP EETLESAAGD
     GFSTATGVAD ALAMAGLPFR TAHEVVAAAA ERAEGTPDLA TLDASAEEVL DASLFEYVSR
     ADVQQTLDPT HSVESRDSTG GPAPAAVTAQ LDEATVELND HRTELNTRTD ALESATEKLA
     AEVAVITRD
//
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