ID   E6R5S2_CRYGW            Unreviewed;       715 AA.
AC   E6R5S2;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   24-JAN-2024, entry version 53.
DE   SubName: Full=Phospholipid:diacylglycerol acyltransferase, putative {ECO:0000313|EMBL:ADV21626.1};
GN   OrderedLocusNames=CGB_D2350W {ECO:0000313|EMBL:ADV21626.1};
OS   Cryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071)
OS   (Filobasidiella gattii) (Cryptococcus bacillisporus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Cryptococcus;
OC   Cryptococcus gattii species complex.
OX   NCBI_TaxID=367775 {ECO:0000313|EMBL:ADV21626.1, ECO:0000313|Proteomes:UP000007805};
RN   [1] {ECO:0000313|EMBL:ADV21626.1, ECO:0000313|Proteomes:UP000007805}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WM276 / ATCC MYA-4071 {ECO:0000313|Proteomes:UP000007805};
RX   PubMed=21304167; DOI=10.1128/mBio.00342-10;
RA   D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA   Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J.,
RA   McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W.,
RA   Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D.,
RA   Schein J., Krzywinski M., Kwon-Chung K.J., Varma A., Wang J., Brunham R.,
RA   Fyfe M., Ouellette B.F., Siddiqui A., Marra M., Jones S., Holt R.,
RA   Birren B.W., Galagan J.E., Cuomo C.A.;
RT   "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT   immunocompetent hosts.";
RL   MBio 2:E342-E342(2011).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=WM276;
RA   D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA   Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J.,
RA   McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W.,
RA   Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D.,
RA   Schein J., Krzywinski M., Kwong-Chung K.J., Varma A., Wang J., Brunham R.,
RA   Fyfe M., Ouellette B.F.F., Siddiqui A., Marra M., Jones S., Holt R.,
RA   Birren B.W., Galagan J.E., Cuomo C.A.;
RT   "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT   immunocompetent hosts.";
RL   MBio 0:0-0(2011).
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DR   EMBL; CP000289; ADV21626.1; -; Genomic_DNA.
DR   RefSeq; XP_003193413.1; XM_003193365.1.
DR   AlphaFoldDB; E6R5S2; -.
DR   GeneID; 10191109; -.
DR   KEGG; cgi:CGB_D2350W; -.
DR   VEuPathDB; FungiDB:CGB_D2350W; -.
DR   eggNOG; KOG2369; Eukaryota.
DR   HOGENOM; CLU_016065_1_0_1; -.
DR   OrthoDB; 589269at2759; -.
DR   Proteomes; UP000007805; Chromosome D.
DR   GO; GO:0008374; F:O-acyltransferase activity; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR003386; LACT/PDAT_acylTrfase.
DR   PANTHER; PTHR11440:SF97; BCDNA.GH02384; 1.
DR   PANTHER; PTHR11440; LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED; 1.
DR   Pfam; PF02450; LCAT; 2.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
KW   Acyltransferase {ECO:0000313|EMBL:ADV21626.1};
KW   Transferase {ECO:0000313|EMBL:ADV21626.1}.
FT   REGION          1..59
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        12..51
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   715 AA;  79850 MW;  C84D7082611D1647 CRC64;
     MPPRKKAVNP SPSLLASPSP STSAVERLPV PATPSSLRQR RSQNTNKEAG GKDNVEFNVK
     LKKNNDGRYH LQEPLLTRLI SVNTPSSRIM MKPHVKTSLP AGKNGFLDAR GILLGIIIAI
     WAMDFSSLPA DMKDVWTSLP TSLDPRDLVS NLTVIDTARR ALENRDFTVG EEVKAEFGIE
     KHHPIILVPG IVSTGLESWG TEVVARNFFR KRLWGTSTMI RAVLSNKERW VQALSIDPET
     GLDPPGFKIR AAQGLDAASE FIQGYWIWQK VVENLATVGY DTNSMDLAAY DWRLAYYNLE
     IRDAYFTRLK NKIEMFHWHN KQKVVLCSHS MKWVESDPIT NGFGGGGGPN WVEEHIEAWI
     NVAGSLLGVS KAMTAFLSGE MRDTVELHPA GSWVLEKFFS RRERAKLFRR WPGSSSMWLK
     GGNRIWGNEN RAPDDPEDAT DTHGRFFSFR HPGVPPDDKS LSEWTVSPNL TVNEAGPYVL
     THTPPSFQRM MESNYSQGFE TDVKKLKENG KDHRKWSNPL EVQLPDAPSM KIYCLYGHGK
     ETERSYWYMQ GEYEEDESRS DAEGDQAYCD ASDPSNGCDN SVINRTALDF PLARRHWIDS
     AVTIKGSSPE VRSGVKFGDG DGTIPVVSLG SMCVKGWKGK TKWNPAGIEV ITQEYKHSPE
     GLDLRGGAQT ADHVDILGAS PLNSAILKIA GGRGDLVTEQ IGSKILEYTE RMDWD
//