ID   E6SEG7_INTC7            Unreviewed;       680 AA.
AC   E6SEG7;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   01-MAY-2013, entry version 15.
DE   SubName: Full=NAD+ synthetase;
DE   Flags: Precursor;
GN   OrderedLocusNames=Intca_3362;
OS   Intrasporangium calvum (strain ATCC 23552 / DSM 43043 / JCM 3097 /
OS   NBRC 12989 / 7 KIP).
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Micrococcineae; Intrasporangiaceae; Intrasporangium.
OX   NCBI_TaxID=710696;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23552 / DSM 43043 / JCM 3097 / NBRC 12989 / 7 KIP;
RX   PubMed=21304734; DOI=10.4056/sigs.1263355;
RA   Del Rio T.G., Chertkov O., Yasawong M., Lucas S., Deshpande S.,
RA   Cheng J.F., Detter C., Tapia R., Han C., Goodwin L., Pitluck S.,
RA   Liolios K., Ivanova N., Mavromatis K., Pati A., Chen A.,
RA   Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA   Rohde M., Pukall R., Sikorski J., Goker M., Woyke T., Bristow J.,
RA   Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.,
RA   Lapidus A.;
RT   "Complete genome sequence of Intrasporangium calvum type strain (7
RT   KIP).";
RL   Stand. Genomic Sci. 3:294-303(2010).
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DR   EMBL; CP002343; ADU49844.1; -; Genomic_DNA.
DR   RefSeq; YP_004100571.1; NC_014830.1.
DR   EnsemblBacteria; ADU49844; ADU49844; Intca_3362.
DR   GeneID; 10086201; -.
DR   KEGG; ica:Intca_3362; -.
DR   PATRIC; 45248368; VBIIntCal153415_3421.
DR   HOGENOM; HOG000051304; -.
DR   KO; K01950; -.
DR   BioCyc; ICAL710696:GH9U-3417-MONOMER; -.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
DR   GO; GO:0003952; F:NAD+ synthase (glutamine-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.620; -; 2.
DR   Gene3D; 3.60.110.10; -; 1.
DR   InterPro; IPR003010; C-N_Hydrolase.
DR   InterPro; IPR014445; Gln-dep_NAD_synthase.
DR   InterPro; IPR022310; NAD/GMP_synthase.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   Pfam; PF00795; CN_hydrolase; 1.
DR   Pfam; PF02540; NAD_synthase; 1.
DR   PIRSF; PIRSF006630; NADS_GAT; 1.
DR   SUPFAM; SSF56317; Ntlse/CNhydtse; 1.
DR   PROSITE; PS50263; CN_HYDROLASE; 1.
PE   4: Predicted;
KW   Complete proteome; Signal.
FT   SIGNAL        1     24       Potential.
FT   CHAIN        25    680       Potential.
FT                                /FTId=PRO_5000668972.
SQ   SEQUENCE   680 AA;  74380 MW;  E6BFFE0188F9162D CRC64;
     MDFASSYAHG FARVAACTLP VAVADPARNA DAVLEQARAC SDEGAAVAIF PELCLTGYAI
     DDLLLQDPLL DAAEEAIARL VEASAELLPV LVVGAPLVRG ARVFNCAVVI HRGAILGVAP
     KAYLPTYREF YERRHFGAGD DQRGQTIEVA GWSVPFGTDL LFRATDLEGF VLGVEVCEDM
     WIPVPPSAEA ALAGATILVN ISGSPITVGR AEDRHLLCRS ASVRCLSAYL YAAAGEGEST
     TDLSWDGQTM IYERGTLLAE TERFPDGPRR SVADIDLDML RQERMRMGTF DDNRRTLTDR
     VSGFRTVEFE VGPPGGDIGL MRKVDRFPFV PDDEARLALD CYEAYNIQVS GLEQRLRAIG
     QPRIVIGVSG GLDSTHALIV AAKAMDRLGR PRSDILAFTM PGFATSAHTK DNAIRLMESL
     GVTWEELDIR PAATEMLKGM DHPFARGEEV YDVTFENVQA GMRTDFLFRI ANQRGGIVLG
     TGDLSELALG WSTYGVGDQM SHYGVNAGVP KTLMQHLIRW VVSSAQFEEH VNATLLSILA
     TEITPELIPA KEGEKPQSTQ AQIGPYSLQD FNLYHVLRWG YRPSKIAFLS WHAWHDAESG
     DWPAGYPAAE RAEYDLATIR RWLEVFLRRF FANQFKRSAL PNGPKVAAGG SLSPRGDWRM
     PSDASGAAWL DELDANVPDA
//