GenomeNet

Database: UniProt/TrEMBL
Entry: E6TX01_BACCJ
LinkDB: E6TX01_BACCJ
Original site: E6TX01_BACCJ 
ID   E6TX01_BACCJ            Unreviewed;       488 AA.
AC   E6TX01;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   09-JUL-2014, entry version 24.
DE   RecName: Full=Probable glycine dehydrogenase (decarboxylating) subunit 2;
DE            EC=1.4.4.2;
DE   AltName: Full=Glycine cleavage system P-protein subunit 2;
DE   AltName: Full=Glycine decarboxylase subunit 2;
DE   AltName: Full=Glycine dehydrogenase (aminomethyl-transferring) subunit 2;
GN   Name=gcvPB; OrderedLocusNames=Bcell_1688;
OS   Bacillus cellulosilyticus (strain ATCC 21833 / DSM 2522 / FERM P-1141
OS   / JCM 9156 / N-4).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=649639;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 21833 / DSM 2522 / FERM P-1141 / JCM 9156 / N-4;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M.,
RA   Hauser L., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N.,
RA   Brumm P., Mead D., Woyke T.;
RT   "Complete sequence of Bacillus cellulosilyticus DSM 2522.";
RL   Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The glycine cleavage system catalyzes the degradation of
CC       glycine. The P protein binds the alpha-amino group of glycine
CC       through its pyridoxal phosphate cofactor; CO(2) is released and
CC       the remaining methylamine moiety is then transferred to the
CC       lipoamide cofactor of the H protein (By similarity).
CC   -!- CATALYTIC ACTIVITY: Glycine + [glycine-cleavage complex H
CC       protein]-N(6)-lipoyl-L-lysine = [glycine-cleavage complex H
CC       protein]-S-aminomethyl-N(6)-dihydrolipoyl-L-lysine + CO(2).
CC   -!- COFACTOR: Pyridoxal phosphate (By similarity).
CC   -!- SUBUNIT: The glycine cleavage system is composed of four proteins:
CC       P, T, L and H. In this organism, the P 'protein' is a heterodimer
CC       of two subunits (By similarity).
CC   -!- SIMILARITY: Belongs to the GcvP family. C-terminal subunit
CC       subfamily.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP002394; ADU29951.1; -; Genomic_DNA.
DR   RefSeq; YP_004094682.1; NC_014829.1.
DR   ProteinModelPortal; E6TX01; -.
DR   EnsemblBacteria; ADU29951; ADU29951; Bcell_1688.
DR   GeneID; 10088251; -.
DR   KEGG; bco:Bcell_1688; -.
DR   PATRIC; 45159309; VBIBacCel7049_1738.
DR   HOGENOM; HOG000239368; -.
DR   KO; K00283; -.
DR   OMA; WTGLMMI; -.
DR   BioCyc; BCEL649639:GHTT-1759-MONOMER; -.
DR   GO; GO:0004375; F:glycine dehydrogenase (decarboxylating) activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0019464; P:glycine decarboxylation via glycine cleavage system; IEA:UniProtKB-HAMAP.
DR   Gene3D; 3.40.640.10; -; 3.
DR   HAMAP; MF_00713; GcvPB; 1.
DR   InterPro; IPR020580; GDC-P_N.
DR   InterPro; IPR020581; GDC_P.
DR   InterPro; IPR023012; GDC_P_su2.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major_sub1.
DR   PANTHER; PTHR11773; PTHR11773; 1.
DR   Pfam; PF02347; GDC-P; 1.
DR   SUPFAM; SSF53383; SSF53383; 1.
PE   1: Evidence at protein level;
KW   Complete proteome; Oxidoreductase; Pyridoxal phosphate.
FT   MOD_RES     274    274       N6-(pyridoxal phosphate)lysine (By
FT                                similarity){EA2}.
SQ   SEQUENCE   488 AA;  54547 MW;  4E68EE6DED97E524 CRC64;
     MIHQQDQALI FEISKEGRIG HSLPEMDVPE VALDELIPSQ FQREEAAELP EVSELQLVRH
     YTALSRRNHG VDSGFYPLGS CTMKYNPKIN EDVARYPGFA HIHPYQAEST IQGALELMYH
     LQNSLAEITG MDEVTLQPAA GAHGEWTGLM MIRAFHEANG DTHRTKVIVP DSAHGTNPAS
     ATVAGFESVT VRSNEKGLVD LDHLKEVVGE DTAALMLTNP NTLGLFEEQI VEMAEIVHNA
     GGKLYYDGAN SNAILGITRP GDMGFDVVHL NLHKTFTTPH GGGGPGSGPV GVKKDLIPFL
     PKPTVVKDGE TYRFEYNLPQ SIGRVKPYYG NFGINVRAYT YIRTMGPEGL RQVSEHAVLN
     ANYMFRRLQP YYDAPYTQHC KHEFVLSGRR QKRLGVRTLD IAKRLLDFGY HPPTIYFPLN
     VEECLMIEPT ETESKETLDE FIDAMIQIAK EAEETPEIVQ EAPHHTVIDR LDETTAARKP
     VLRYTKED
//
DBGET integrated database retrieval system