ID E9H9X8_DAPPU Unreviewed; 706 AA.
AC E9H9X8;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Mes-4-like protein {ECO:0000313|EMBL:EFX71479.1};
GN Name=MES-4 {ECO:0000313|EMBL:EFX71479.1};
GN ORFNames=DAPPUDRAFT_299753 {ECO:0000313|EMBL:EFX71479.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX71479.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX71479.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL732609; EFX71479.1; -; Genomic_DNA.
DR AlphaFoldDB; E9H9X8; -.
DR STRING; 6669.E9H9X8; -.
DR EnsemblMetazoa; EFX71479; EFX71479; DAPPUDRAFT_299753.
DR KEGG; dpx:DAPPUDRAFT_299753; -.
DR eggNOG; KOG1081; Eukaryota.
DR HOGENOM; CLU_004494_1_0_1; -.
DR InParanoid; E9H9X8; -.
DR OMA; MARIKYD; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0000785; C:chromatin; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0046975; F:histone H3K36 methyltransferase activity; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR CDD; cd15566; PHD3_NSD; 1.
DR CDD; cd15567; PHD4_NSD; 1.
DR CDD; cd15568; PHD5_NSD; 1.
DR CDD; cd05838; PWWP_NSD_rpt2; 1.
DR CDD; cd19173; SET_NSD; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 4.
DR InterPro; IPR006560; AWS_dom.
DR InterPro; IPR041306; C5HCH.
DR InterPro; IPR003616; Post-SET_dom.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR22884:SF514; DOMAIN PROTEIN, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR22884; SET DOMAIN PROTEINS; 1.
DR Pfam; PF17907; AWS; 1.
DR Pfam; PF17982; C5HCH; 1.
DR Pfam; PF00855; PWWP; 1.
DR Pfam; PF00856; SET; 1.
DR SMART; SM00570; AWS; 1.
DR SMART; SM00249; PHD; 5.
DR SMART; SM00508; PostSET; 1.
DR SMART; SM00293; PWWP; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 4.
DR SUPFAM; SSF82199; SET domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS51215; AWS; 1.
DR PROSITE; PS50868; POST_SET; 1.
DR PROSITE; PS50812; PWWP; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS01359; ZF_PHD_1; 2.
DR PROSITE; PS50016; ZF_PHD_2; 2.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000000305};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 168..213
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 218..280
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT DOMAIN 352..403
FT /note="AWS"
FT /evidence="ECO:0000259|PROSITE:PS51215"
FT DOMAIN 405..522
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 536..552
FT /note="Post-SET"
FT /evidence="ECO:0000259|PROSITE:PS50868"
FT DOMAIN 584..631
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
SQ SEQUENCE 706 AA; 80004 MW; 6170D8D806B9189A CRC64;
MPCNKCRSVY HPECIKENSE EASNAETFLC LNCNPSTSSN CCLCRKSDGE LLICNLKLCG
RRYHRHCLKL FHSPSIKQEK PASQFTCPAH YCHTCVADLN ELNQVEKKLL RCIHCPTAYH
PSEKCLAAGC VQLSTFQMKC FKHVENRDVV VKKSKKEKKT IIPNHYNVNW CIVCSEGGSL
ICCERCPSSL HTHCAGLEKE PDGSFICYEC TSGKTILYGD IVWIKMSIYR WWPGRVFPLD
EIPPKHQKYQ PKAGEFLVYF YGSNNSAYVY RGQVFLYQDG DQGCKVKSKN KLGDDFKRAL
EDVTPAFQLR KQVLVERTAE RQAKINVKPP HYNKIRSNKP VGKVRMQDSS PYSSAICDCE
VKEGQPTCGP DSECINRILL FECDPNVCAG RKLCQNQRFQ QRLSPPLYPF NTGGKGWGLK
SHADIKKGDF VVEYVGEIID NNEFRRRLKA KQDAQDEAYY FLTLDNNRMI DAGPSGNFAR
FMNHSCQPNC ETQKWTVLGD TRIGLFAVVD IPAHAELTFN YQLECAQDVA NESNQRQQPC
HCGAPNCAGF IGAKPKQLKV EKVKVVKGKK KKQQRKLEKE TVSEDFCFRC TEGGELVVCD
FKNCSKVYHL ECLKLSAPPK GQWTCPWHHC DVCGRKASQF CSVCPNSLCS THALEVDMQS
HERLGLICNE HSQEETEFFL KRRLEEDAAT VVTTSPEPSS SETSSC
//
