ID E9QYY1_ASPFU Unreviewed; 385 AA.
AC E9QYY1;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 06-MAR-2013, entry version 17.
DE SubName: Full=Isocitrate dehydrogenase, NAD-dependent;
DE EC=1.1.1.41;
GN ORFNames=AFUA_1G12800;
OS Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS A1100) (Aspergillus fumigatus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae;
OC mitosporic Trichocomaceae; Aspergillus.
OX NCBI_TaxID=330879;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100;
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S.,
RA Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W.,
RA Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S.,
RA Farman M.L., Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R.,
RA Fosker N., Fraser A., Garcia J.L., Garcia M.J., Goble A.,
RA Goldman G.H., Gomi K., Griffith-Jones S., Gwilliam R., Haas B.J.,
RA Haas H., Harris D.E., Horiuchi H., Huang J., Humphray S., Jimenez J.,
RA Keller N., Khouri H., Kitamoto K., Kobayashi T., Konzack S.,
RA Kulkarni R., Kumagai T., Lafton A., Latge J.-P., Li W., Lord A.,
RA Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y., Molina M.,
RA Monod M., Mouyna I., Mulligan S., Murphy L.D., O'Neil S., Paulsen I.,
RA Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA Ronning C.M., Rutter S., Salzberg S.L., Sanchez M.,
RA Sanchez-Ferrero J.C., Saunders D., Seeger K., Squares R., Squares S.,
RA Takeuchi M., Tekaia F., Turner G., Vazquez de Aldana C.R., Weidman J.,
RA White O., Woodward J.R., Yu J.-H., Fraser C.M., Galagan J.E., Asai K.,
RA Machida M., Hall N., Barrell B.G., Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
CC -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC dehydrogenases family.
CC -!- CAUTION: The sequence shown here is derived from an
CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC preliminary data.
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DR EMBL; AAHF01000004; EAL90612.1; -; Genomic_DNA.
DR RefSeq; XP_752650.1; XM_747557.1.
DR ProteinModelPortal; E9QYY1; -.
DR SMR; E9QYY1; 42-385.
DR PRIDE; E9QYY1; -.
DR GeneID; 3510346; -.
DR KEGG; afm:AFUA_1G12800; -.
DR KO; K00030; -.
DR OMA; NQKQVTR; -.
DR GO; GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR Gene3D; 3.40.718.10; -; 1.
DR InterPro; IPR019818; IsoCit/isopropylmalate_DH_CS.
DR InterPro; IPR001804; Isocitrate/isopropylmalate_DH.
DR InterPro; IPR004434; Isocitrate_DH_NAD.
DR InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR PANTHER; PTHR11835; PTHR11835; 1.
DR Pfam; PF00180; Iso_dh; 1.
DR TIGRFAMs; TIGR00175; mito_nad_idh; 1.
DR PROSITE; PS00470; IDH_IMDH; 1.
PE 3: Inferred from homology;
KW Complete proteome; Oxidoreductase; Reference proteome.
SQ SEQUENCE 385 AA; 41727 MW; DF8B9F70C25627DE CRC64;
MISARNFVAP ARQCLRTTRV SSGFASHLSQ LRGYASAADD RVAKFKGQKG PDGKYTVTLI
EGDGIGPEIA QSVKDIFAAA KAPIKWEPVD VTPILKDGKT TIPEEAIKSV QKNYVALKGP
LATPVGKGHV SLNLTLRRTF NLFANLRPCR SVAGYKTPYD NVDTVLIREN TEGEYSGIEH
VVVDGVVQSI KLITREASER VLRFAFQYAR SVNKKKVRVV HKATIMKMSD GLFLNTAREI
AKEFPDIEFD AELLDNSCLK IVTDPTPYND KVLVMPNLYG DILSDMCAGL IGGLGLTPSG
NIGDECSIFE AVHGSAPDIA GKGLANPTAL LLSSIMMLQH MGLHEHAARI QKATFDTLAE
GKTLTGDLGG KAKTHEYAEA ICKRL
//
