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Database: UniProt/TrEMBL
Entry: F0Y1J6_AURAN
LinkDB: F0Y1J6_AURAN
Original site: F0Y1J6_AURAN 
ID   F0Y1J6_AURAN            Unreviewed;       506 AA.
AC   F0Y1J6;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   07-JUN-2017, entry version 25.
DE   RecName: Full=Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex {ECO:0000256|RuleBase:RU003423};
DE            EC=2.3.1.- {ECO:0000256|RuleBase:RU003423};
GN   Name=DLA1 {ECO:0000313|EMBL:EGB10928.1};
GN   ORFNames=AURANDRAFT_58776 {ECO:0000313|EMBL:EGB10928.1};
OS   Aureococcus anophagefferens (Harmful bloom alga).
OC   Eukaryota; Stramenopiles; Pelagophyceae; Pelagomonadales; Aureococcus.
OX   NCBI_TaxID=44056 {ECO:0000313|Proteomes:UP000002729};
RN   [1] {ECO:0000313|EMBL:EGB10928.1, ECO:0000313|Proteomes:UP000002729}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCMP 1984 {ECO:0000313|Proteomes:UP000002729};
RX   PubMed=21368207; DOI=10.1073/pnas.1016106108;
RA   Gobler C.J., Berry D.L., Dyhrman S.T., Wilhelm S.W., Salamov A.,
RA   Lobanov A.V., Zhang Y., Collier J.L., Wurch L.L., Kustka A.B.,
RA   Dill B.D., Shah M., VerBerkmoes N.C., Kuo A., Terry A., Pangilinan J.,
RA   Lindquist E.A., Lucas S., Paulsen I.T., Hattenrath-Lehmann T.K.,
RA   Talmage S.C., Walker E.A., Koch F., Burson A.M., Marcoval M.A.,
RA   Tang Y.Z., Lecleir G.R., Coyne K.J., Berg G.M., Bertrand E.M.,
RA   Saito M.A., Gladyshev V.N., Grigoriev I.V.;
RT   "Niche of harmful alga Aureococcus anophagefferens revealed through
RT   ecogenomics.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:4352-4357(2011).
CC   -!- COFACTOR:
CC       Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC         Evidence={ECO:0000256|RuleBase:RU003423};
CC   -!- SIMILARITY: Belongs to the 2-oxoacid dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003423}.
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DR   EMBL; GL833123; EGB10928.1; -; Genomic_DNA.
DR   RefSeq; XP_009034498.1; XM_009036250.1.
DR   EnsemblProtists; EGB10928; EGB10928; AURANDRAFT_58776.
DR   GeneID; 20222660; -.
DR   KEGG; aaf:AURANDRAFT_58776; -.
DR   InParanoid; F0Y1J6; -.
DR   KO; K00627; -.
DR   OMA; IVSWSAA; -.
DR   Proteomes; UP000002729; Unassembled WGS sequence.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
DR   GO; GO:0008152; P:metabolic process; IEA:InterPro.
DR   Gene3D; 4.10.320.10; -; 2.
DR   InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR   InterPro; IPR000089; Biotin_lipoyl.
DR   InterPro; IPR004167; E3-bd.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   Pfam; PF00198; 2-oxoacid_dh; 1.
DR   Pfam; PF00364; Biotin_lipoyl; 1.
DR   Pfam; PF02817; E3_binding; 2.
DR   SUPFAM; SSF47005; SSF47005; 2.
DR   SUPFAM; SSF51230; SSF51230; 1.
DR   PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|RuleBase:RU003423};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002729};
KW   Lipoyl {ECO:0000256|RuleBase:RU003423};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002729};
KW   Transferase {ECO:0000256|RuleBase:RU003423}.
FT   DOMAIN       33    112       Lipoyl-binding. {ECO:0000259|PROSITE:
FT                                PS50968}.
SQ   SEQUENCE   506 AA;  50297 MW;  3ED404536773E5BB CRC64;
     MLLLLVAGAA ALRAPSGLRC PRFTGATVLR SSTTEIMMPA LSSTMTSGRV VSWLKNVGDK
     IEAGDPIIVV ESDKADMEVE SYDEGARRRY LAAVFVGEGE DADVGVPVGV LAETPEEAKA
     FSGGPSGGGA AAAEPAAPAA PAAPAAPAGD APESVAVAAY GAPAAAAAPA AAAAAPAAAA
     PAAAPAAAAK APAGDRVAAS GYAKKVAAGA GVDVAAVAGT GPGGRVVARD AAKLAKSKNL
     DLAGVAGTGR FGRVTEDDVK KALGIAEPAK PKLVPAGGPA PPPAGVVDMT GMQKAIAKNM
     EATLAVPVFR VSKTVRTDAF DALYQKLKPD GVTVSALLAK AVAGALVKTP LMNAKYEPGA
     FSYNGDVNVA MAVALDGGLI TPTLRNADQL SLADLSAEWK SLVGKAKSGS LKPEEYTTGT
     FTISNLGMFD VAQFDAILPP GQGAILAISS SKNVVVPMPG SLLGVGIEKQ MTVTVTCDHR
     IISGADAAVF LKDFAAAVEN PATLTK
//
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