ID F0ZX69_DICPU Unreviewed; 1816 AA.
AC F0ZX69;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Clu domain-containing protein {ECO:0000259|PROSITE:PS51823};
GN ORFNames=DICPUDRAFT_89640 {ECO:0000313|EMBL:EGC31469.1};
OS Dictyostelium purpureum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=5786 {ECO:0000313|EMBL:EGC31469.1, ECO:0000313|Proteomes:UP000001064};
RN [1] {ECO:0000313|Proteomes:UP000001064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QSDP1 {ECO:0000313|Proteomes:UP000001064};
RX PubMed=21356102; DOI=10.1186/gb-2011-12-2-r20;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Sucgang R., Kuo A., Tian X., Salerno W., Parikh A., Feasley C.L., Dalin E.,
RA Tu H., Huang E., Barry K., Lindquist E., Shapiro H., Bruce D., Schmutz J.,
RA Salamov A., Fey P., Gaudet P., Anjard C., Babu M.M., Basu S.,
RA Bushmanova Y., van der Wel H., Katoh-Kurasawa M., Dinh C., Coutinho P.M.,
RA Saito T., Elias M., Schaap P., Kay R.R., Henrissat B., Eichinger L.,
RA Rivero F., Putnam N.H., West C.M., Loomis W.F., Chisholm R.L., Shaulsky G.,
RA Strassmann J.E., Queller D.C., Kuspa A., Grigoriev I.V.;
RT "Comparative genomics of the social amoebae Dictyostelium discoideum and
RT Dictyostelium purpureum.";
RL Genome Biol. 12:R20.1-R20.23(2011).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL871252; EGC31469.1; -; Genomic_DNA.
DR RefSeq; XP_003292008.1; XM_003291960.1.
DR STRING; 5786.F0ZX69; -.
DR EnsemblProtists; EGC31469; EGC31469; DICPUDRAFT_89640.
DR GeneID; 10505756; -.
DR KEGG; dpp:DICPUDRAFT_89640; -.
DR eggNOG; KOG1840; Eukaryota.
DR InParanoid; F0ZX69; -.
DR OMA; SGHMEMS; -.
DR OrthoDB; 1328255at2759; -.
DR Proteomes; UP000001064; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0048312; P:intracellular distribution of mitochondria; IBA:GO_Central.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR033646; CLU-central.
DR InterPro; IPR025697; CLU_dom.
DR InterPro; IPR027523; CLU_prot.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR12601:SF15; CLU DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12601; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT EIF-3; 1.
DR Pfam; PF13236; CLU; 1.
DR Pfam; PF12807; eIF3_p135; 1.
DR Pfam; PF13424; TPR_12; 1.
DR SMART; SM00028; TPR; 4.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51823; CLU; 1.
DR PROSITE; PS50005; TPR; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000001064};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 323..586
FT /note="Clu"
FT /evidence="ECO:0000259|PROSITE:PS51823"
FT REPEAT 935..968
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 977..1010
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 232..254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 283..302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 529..549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1399..1500
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1548..1594
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1616..1648
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1730..1783
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1788..1815
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 533..548
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1441..1500
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1552..1594
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1616..1635
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1740..1776
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1816 AA; 202820 MW; B26610D1E5FD28E5 CRC64;
MSSYITPSSS AYIDENNTNN NNNSDASIYI DDTTSTTSTN NYQYKKTIVN NNSGNIKISN
SSFNSNTTNS NIGSNIYNNE DIWYYLKKES YSCISHIAEF QSYHLNQENK SVCSYIIDPS
TTCSSSYSKI YSVTSENNGN AFNVYTSNSN SSYSINGASI YGNAKNSIYN TNSVSYGQPT
TAYVMKESLW KNDGSSASSS YSSNYIQPLS VSNDQSLNSI INMTNSSSYG GYPNLNNSAN
NNKLQDSGSS NGSSNYIEQY LDPINTKSNN LMDSSYHYIF HNHQNSSSSS SSPPTLLNSA
GSTHLNSSAN LINSTSSTSS GLLNSTNSTA SLNHLQQQQP QEDVLPWNES FQQILDKPIK
SSEEELERNL NISNMSQLLA NQAIKYVKTL VREVHLSPED KTIKPYQIGG FAGGEKYKID
SMFIKFALNP FKIYEGNNTL SYFANKSAGH ELKSISVLLS CGLNLHVPLI CLLNYRGFRL
SVISELPITS NTIVFGSSNA GATIHDNETV SKMMVKIGEI LNLKAHDAKE NQKSPPLISS
NNSESKKPPK QVKIPLAIDI EGHYGTDGRY YIVDSARLLP PEKPQIGITG GFLYKLFREE
FVKKYETQLC SDSFSNFQVV DLEFYNREIE KATNYLITKI IPNFVDTVLL KENTVLKRLN
LKELLHSNGI NLRYYGLVLY QLVAAGNSLK IVLNRIEVLK GKVIVEMLSR LLRFVVFSEM
RKLNEQEDRE HLQIVLNHLN LILPVVPSVN SHLYWVNFIA NALSAKFTSS FPDMPQASLV
RSLITESYGL FTLFNTQLKL RYKFLKKFSQ LTGIVVSPHY LGVLKQISNN TGFNVAIPIL
QLSDFIEITV IVKHMKILST FKAFEQFSDA EKYYLTELKY KIDKLGEEHT QVAQVHVNLS
DLYTSNSYLK EAQGHLIQAV DIYIKRFGSE DLGTVTTKEK LGLVLIKRNK IDKAAEIFKE
VLEVKKKILS TDNIEIADTY DNLAWVYQNK NDFQQSIANY SEALRIKNEK TGNSLTTAKT
LNNIGHLFIT THEVRKAIEI FLKVREIFIA HRGPDHSDVA IAEDNLGIVY AKNRDYVLSE
KSLCNAIQIR TKKLGKNSAL VATSQNHLAQ LYLSWDSNKN KQSESVPLFK SSIKIVDQLP
DRYSRAFMRY SFSKYYRIKK DKNEELKLIN ESLQILEIHN IDSELIHTLR ERKDNLTKSG
ISKLFGWING PAKVSNSSVP IVNHNAIESQ NQNSGHMEMT SNTFASGGSG NIPKEWQALF
DEIGITNEEM SDPQYTADLQ SIIQEALMEK SKENKRTKGK RKVLKKKDVM DTVNNFKNEV
RKIHETVSTT NSIIHSNIKK SLEKDSRVMK KETDSECSIK KPALSKKIAP VKVTPPVIVK
TVAPPNIYRK EKSQPPAINL FSSLPSRPAP PIPSSSDIPL GAINKPYAAP LRSSSAPPPG
GAAPTASPKP VSVAPPVPPK TVAPPIPPKP PQASPPPPPP AIPTTPLPPP PTIPITPLPP
LPVESMVFLD TAPITPLPPL PVHEIVQPTD MEVQSSLFKK QELKKPSPFS WFKTKSPRTS
ISPSSSSFVS RESSLSAPQP TFSASSQSTS LYPKFDLDNE PRLSLLSYTP PAPLTSSAPP
VPLTSSAPPA PLTSSAPPVS SASQQTRLRK VVNISHTGNI YHTPMEYTAP TSNTSKMYPN
LQSQQLQQIE KLQEINIYDA HGMSRDLKNL INDDIVTFND DDDEKEMGEA IGGLKINEDE
SSDQEEEEIH YEDDGEDEGE DYEEEEEEDD DDEEESNKQF YWPHLTNLLN KEDIVNTIKQ
KLKEKRENLN LLKNLK
//
