ID F2JTL9_MARM1 Unreviewed; 208 AA.
AC F2JTL9;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 03-APR-2013, entry version 9.
DE RecName: Full=Thymidylate kinase;
DE EC=2.7.4.9;
DE AltName: Full=dTMP kinase;
GN Name=tmk; OrderedLocusNames=Marme_2292;
OS Marinomonas mediterranea (strain ATCC 700492 / JCM 21426 / NBRC 103028
OS / MMB-1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales;
OC Marinomonas.
OX NCBI_TaxID=717774;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1;
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L.,
RA Pitluck S., Teshima H., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I.,
RA Lucas-Elio P., Johnston A.W.B., Sanchez-Amat A., Woyke T.;
RT "Complete sequence of Marinomonas mediterranea MMB-1.";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Phosphorylation of dTMP to form dTDP in both de novo and
CC salvage pathways of dTTP synthesis (By similarity).
CC -!- CATALYTIC ACTIVITY: ATP + dTMP = ADP + dTDP.
CC -!- SIMILARITY: Belongs to the thymidylate kinase family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; CP002583; ADZ91533.1; -; Genomic_DNA.
DR RefSeq; YP_004313369.1; NC_015276.1.
DR EnsemblBacteria; ADZ91533; ADZ91533; Marme_2292.
DR GeneID; 10336370; -.
DR KEGG; mme:Marme_2292; -.
DR PATRIC; 47229420; VBIMarMed159599_2362.
DR KO; K00943; -.
DR GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR GO; GO:0004798; F:thymidylate kinase activity; IEA:HAMAP.
DR GO; GO:0006233; P:dTDP biosynthetic process; IEA:InterPro.
DR GO; GO:0006235; P:dTTP biosynthetic process; IEA:HAMAP.
DR HAMAP; MF_00165; Thymidylate_kinase; 1; -.
DR InterPro; IPR018095; Thymidylate_kin_CS.
DR InterPro; IPR018094; Thymidylate_kinase.
DR PANTHER; PTHR10344; PTHR10344; 1.
DR TIGRFAMs; TIGR00041; DTMP_kinase; 1.
DR PROSITE; PS01331; THYMIDYLATE_KINASE; 1.
PE 3: Inferred from homology;
KW ATP-binding; Complete proteome; Kinase; Nucleotide biosynthesis;
KW Nucleotide-binding; Transferase.
FT NP_BIND 10 17 ATP (By similarity).
SQ SEQUENCE 208 AA; 22689 MW; 652044927BE3CCD2 CRC64;
MKGKFITLEG GEGSGKSTAI ACLEQWMKAQ GIPYLLTREP GGTPLAEEIR QVVLSKRDET
VNSITELLLV FAARAQHVAQ KIAPALESGV WVISDRFIDS SYVYQGVARG LDIEDIDSLV
RLAVGASLPD KTILLDVPVS VGMARVSART GNDRLDGEST QFHEMVRAGF LDLAKRDSHR
ISIVDASVPQ ENVFEQIVTI LEQVKQAK
//
