ID F2NVV6_TRES6 Unreviewed; 794 AA.
AC F2NVV6;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Beta-galactosidase {ECO:0000313|EMBL:AEB14683.1};
DE EC=3.2.1.23 {ECO:0000313|EMBL:AEB14683.1};
GN OrderedLocusNames=Tresu_1792 {ECO:0000313|EMBL:AEB14683.1};
OS Treponema succinifaciens (strain ATCC 33096 / DSM 2489 / 6091).
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Treponemataceae;
OC Treponema.
OX NCBI_TaxID=869209 {ECO:0000313|EMBL:AEB14683.1, ECO:0000313|Proteomes:UP000006852};
RN [1] {ECO:0000313|EMBL:AEB14683.1, ECO:0000313|Proteomes:UP000006852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33096 / DSM 2489 / 6091
RC {ECO:0000313|Proteomes:UP000006852};
RX PubMed=21886863;
RA Han C., Gronow S., Teshima H., Lapidus A., Nolan M., Lucas S., Hammon N.,
RA Deshpande S., Cheng J.F., Zeytun A., Tapia R., Goodwin L., Pitluck S.,
RA Liolios K., Pagani I., Ivanova N., Mavromatis K., Mikhailova N.,
RA Huntemann M., Pati A., Chen A., Palaniappan K., Land M., Hauser L.,
RA Brambilla E.M., Rohde M., Goker M., Woyke T., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P., Detter J.C.;
RT "Complete genome sequence of Treponema succinifaciens type strain (6091).";
RL Stand. Genomic Sci. 4:361-370(2011).
RN [2] {ECO:0000313|Proteomes:UP000006852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33096 / DSM 2489 / 6091
RC {ECO:0000313|Proteomes:UP000006852};
RA Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Peters L., Kyrpides N., Mavromatis K., Ivanova N., Ovchinnikova G.,
RA Teshima H., Detter J.C., Tapia R., Han C., Land M., Hauser L.,
RA Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Gronow S.,
RA Wellnitz S., Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete genome of chromosome of Treponema succinifaciens DSM 2489.";
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401, ECO:0000256|RuleBase:RU361154}.
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DR EMBL; CP002631; AEB14683.1; -; Genomic_DNA.
DR RefSeq; WP_013701964.1; NC_015385.1.
DR AlphaFoldDB; F2NVV6; -.
DR STRING; 869209.Tresu_1792; -.
DR KEGG; tsu:Tresu_1792; -.
DR eggNOG; COG3250; Bacteria.
DR HOGENOM; CLU_006501_5_1_12; -.
DR OrthoDB; 9801077at2; -.
DR Proteomes; UP000006852; Chromosome.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR023230; Glyco_hydro_2_CS.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR42732:SF1; BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00719; GLYCOSYL_HYDROL_F2_1; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361154};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361154};
KW Reference proteome {ECO:0000313|Proteomes:UP000006852}.
FT DOMAIN 44..157
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 160..256
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 261..530
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
SQ SEQUENCE 794 AA; 89625 MW; 95FCA4D0BBCC6877 CRC64;
MKDRIYFNNG WEFSPSFNEK MLDSKYKGKF EQVRIPHSVC ETPFNGFDES EYQKLSIYRK
FFKTEKEWAG KKILLTIEGA AHQCDVFLNG KFLARHSCGY TAFTVDLTDS LLPAGRNNLL
ALKLDSRESL NIPPFGFVID YMTYGGIYRD VYLDIKNPIY IEDIFIKTKA SHFETEITLN
SSDAEGYSIV QRVESSSSVV AQINTGVPGN KILTAADAQP VHPWTLEQPV LYNLVTELIN
PKGKIADKKN VRFGFREIKF DETGFYLNGK KIKLRGLNRH QSYPYVGYAM PKNIQKEDAD
ILKLELGVNY VRTSHYPQSK YFIERCDELG ILVFTEFPGW QHIGDDAWKA QALENEDEMI
SQYRNHPSVF MWGVRINESK DDDEFYKATN FLAHKTDSTR PTGGVRCIKN SNLLEDVYTY
NDFSHSGKNA GSLDKIKVTK SHGGYLVTEH SGHMFPTKSF DTEQRRTEHA IRHATVLDSV
AGHDDCAGSS GWCAFDYNTH KEFGSGDRIC YHGVMDMFRN PKLAAAVYKS QEDFTGDFIE
VNSNMSIGEY NEGLLGDLWI FTNADSVKLF VNNTFIKEFK ASDSPFKNLA HGPILVDDII
GNRLIDEEGI SAKNSEKIKE LIFAIKKFGQ NSLSAKYKLE AAKLFAMRVI SKEKLIALFG
KYISNWGGES SSYKFEAIKN GKTVKTLVKS MCKNASLKTQ VSRTILIEEE TYDVAEVHLR
AEDENGNLQS FIQEAVLAEA EGAIEIIGPQ AVSLKGGMSG IYVKTTGTAG RGTLKITDWQ
GKETKISFTV KIKR
//
